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  • Blood levels  (1)
  • Sister chromatid exchange  (1)
  • Springer  (2)
  • 1985-1989  (2)
Document type
Keywords
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  • Springer  (2)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Normal sister chromatid exchange in lymphocytes from patients with multiple epidermal cancer? (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 180-183 
    Details
    ISSN: 1432-069X
    Keywords: Multiple epidermal cancer ; Sister chromatid exchange ; Lymphocyte UVC sensitivity ; Lymphocyte X-ray sensitivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Exposure to toxins in the environment and due to personal habits, e. g., tobacco smoking, may increase the rate of spontaneous sister chromatid exchange (SCE). The SCE in lymphocytes from a group of 31 patients with multiple epidermal cancer, who in the past had been exposed to various skin carcinogens, as a whole exceeded that of a control group — matched by sex, age, and smoking habits — but the difference was not statistically significant (p=0.08). The individual SCE in these patients was also statistically independent of the nature of the carcinogenic exposure. We were unable to detect correlations between the SCE and UVC-radiation induced DNA synthesis, UVC-radiation tolerance, or rate of X-ray damage repair. This suggests that the molecular mechanisms involved in SCE induction and in repair of radiation damage are basically independent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00413254
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Occupational chronic exposure to organic solvents XI. Alkylbenzene exposure of varnish workers: effects on hematopoetic system (1985)
    Springer
    International archives of occupational and environmental health 56 (1985), S. 307-321 
    Details
    ISSN: 1432-1246
    Keywords: Xylenes ; Ethylbenzene ; Spraymen ; Blood levels ; Metabolite ; Excretion ; Changes in blood cell counts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirty-five spraymen, who were varnishing vehicles with alkyd-, phenol- and polyestervarnishes, which were dissolved in solvent mixtures mainly containing o-, m-, p-xylene and ethylbenzene, have been investigated. The concentrations of these solvents in air were 2.1, 7.9, 2.8 and 4.0 ppm on average. The levels of alkylbenzenes in blood and those of their metabolites in urine have been determined. At two of the six working places the spraymen were additionally exposed to n-butanol, respectively 1,1,1-trichloroethane, and several C9-aromatic hydrocarbons. Some of the lacquers contained lead pigments. Alterations of blood cell counts have been observed under the described conditions of exposure. On average the number of lymphocytes was higher than that of segmented granulocytes. Erythrocytes and hemoglobin level of the spraymen were lower than those of the controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00405272
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    Paper (German National Licenses)
    Fulltext
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