ISSN:
1432-2307
Keywords:
Liver
;
Copper storage
;
Indian childhood cirrhosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A female child of non-consanguineous, healthy German parents fell ill at the age of 7 months with a progressive liver disease leading to irreversible hepatic failure 3 months later. Histological examination revealed severe liver cell necrosis, excessive Mallory body formation and veno-occlusive-like changes associated with massive storage of copper, similar to Indian childhood cirrhosis (ICC). Chronic copper contamination of drinking water was the only detectable aetiological factor. The study illustrates that ICC most probably is an environmental disease, also occurring outside the Indian subcontinent, and is likely to be underdiagnosed in the Western world.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00713384
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