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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 238 (1991), S. 203-208 
    ISSN: 1432-1459
    Keywords: Huntington's disease ; Sleep EEG ; Basal ganglia disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nocturnal sleep was studied in 16 inpatients with Huntington's disease. In comparison with healthy controls, patients exhibited a disturbed sleep pattern with increased sleep onset latency, reduced sleep efficiency, frequent nocturnal awakenings, more time spent awake and less slow wave sleep. These abnormalities correlated in part with duration of illness, severity of clinical symptoms, and degree of atrophy of the caudate nucleus. Patients showed an increased density of sleep spindles.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 240 (1991), S. 331-333 
    ISSN: 1433-8491
    Keywords: Bulimia nervosa ; Anorexia nervosa ; Caudate nuclei ; Glucose metabolism ; Positron emission tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Regional cerebral glucose metabolism was measured with18F-2-fluoro-2-deoxyglucose and positron emission tomography in nine patients with bulimia nervosa and in seven patients with anorexia nervosa. Relative caudate glucose metabolism (caudate glucose metabolism divided by global cerebral glucose metabolism) was significantly higher in anorexia nervosa than in bulimia nervosa, suggesting that caudate hyperactivity is characteristic of the anorexic state. Whether increased caudate function is a consequence of anorexic behaviour or whether it is directly involved in the pathogenesis of anorexia nervosa is an issue still to be clarified.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 30 (1990), S. 679-696 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The numerical simulation of conduction heat transfer in arbitrarily-shaped regions is relevant to many engineering applications including the casting of plastics and metals, cold region problems and latent heat storage. This class of problem offers its particular challenges. The accurate computational simulation of conduction with thermally-dependent properties requires a solution technique with good conservation properties. The boundary-fitted co-ordinates of an arbitrary solution domain typically yield grids which are non-orthogonal and which, consequently, make energy conservation difficult to model.In the current article, a technique is described to simulate accurately the conduction heat transfer in materials of thermally-dependent properties in irregular domains. The method combines boundary-fitted co-ordinates with the finite volume method, FVM, to produce a numerical technique which will accurately solve this non-linear conduction problem using a grid which may be highly skewed. This capability is achieved through a unique treatment of the cross-derivative terms that arise when the heat conduction equation is transformed to a non-orthogonal grid. The cross-derivative terms represent the non-normal components of the heat fluxes into the skewed control volume. The tangent components of the heat fluxes are interpreted in a special way to produce finite difference expressions which accurately model the cross-derivative partial.The numerical procedure is validated by comparing it against a purely analytical mathematical method. Although the numerical results have been obtained using a highly skewed grid, they exhibit close agreement with the analytically-derived solution.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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