ISSN:
1434-4726
Keywords:
Chronic non-allergic rhinitis
;
Kinins
;
Methacholine challenge
;
Muscarinic receptor stimulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Following nasal challenges with the muscarinic neurotransmitter methacholine in 14 patients with chronic non-allergic rhinitis, kinin generation was induced. This occurrence was inhibited by pretreatment with anticholinergic agents (ipratropium bromide) and by an overdose of neurotransmitter, indicating that a muscarinic receptor is stimulating the liberation of kinin. These observations suggest that patients with chronic non-allergic rhinitis exhibit cholinergic neurotransmitter-induced kinin generation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00179380
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