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  • 1
    Electronic Resource
    Electronic Resource
    Generalization of the Calogero–Cohn bound on the number of bound states (1996)
    College Park, Md. : American Institute of Physics (AIP)
    Journal of Mathematical Physics 37 (1996), S. 1106-1114 
    Details
    ISSN: 1089-7658
    Source: AIP Digital Archive
    Topics: Mathematics , Physics
    Notes: It is shown that for the Calogero–Cohn-type upper bounds on the number of bound states of a negative spherically symmetric potential V(r), in each angular momentum state, that is, bounds containing only the integral ∫∞0||V(r)||1/2 dr, the condition V′(r)≥0 is not necessary, and can be replaced by the less stringent condition (d/dr)[r1−2p(−V)1−p]≤0, 1/2≤p〈1, which allows oscillations in the potential. The constants in the bounds are accordingly modified, depend on p and l, and tend to the standard value for p=1/2. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.531450
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  • 2
    Electronic Resource
    Electronic Resource
    Serum Surfactant Protein A Levels in Healthy Individuals Are Increased in Smokers (1998)
    Springer
    Lung 176 (1998), S. 355-361 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Surfactant protein—Smoking—Alveolar type 2 cells—Age.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Serum levels of surfactant protein A (SP-A) were studied in 237 healthy subjects in relation to sex, age, and smoking habits. SP-A values in male smokers were significantly higher than those in male nonsmokers (p 〈 0.001). The amount of cigarette smoking did not correlate significantly with SP-A values, however. SP-A values in young nonsmoking males and females were somewhat lower than those in older, but without significant difference. No significant difference in values was found between the sexes. We conclude that (1) smoking increases serum levels of SP-A, and (2) SP-A serum levels are not affected by age and sex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00007617
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  • 3
    Electronic Resource
    Electronic Resource
    Detection of Epstein-Barr virus infection in the epithelial cells and lymphocytes of non-neoplastic tonsils by in situ hybridization and in situ PCR (1998)
    Springer
    Archives of virology 143 (1998), S. 803-813 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  Non-neoplastic tonsils were analyzed for detection of Epstein-Barr virus (EBV)-positive cells by in situ hybridization and in situ PCR. EBV-encoded small nuclear RNA 1(EBER1)-positive cells were found in 28.2% of the tonsils and were evenly localized in the extrafollicular area and within germinal centers. Latent membrane protein 1 (LMP1)-positive cells were also dispersed in the extrafollicular and germinal center. Using in situ DNA-DNA hybridization, the EBV-positive signals were observed in the upper epithelial cell layers of the tonsils. In addition, in situ PCR detected EBV DNA-positive cells in the lower epithelial cell layers and lymphoid cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007050050332
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  • 4
    Electronic Resource
    Electronic Resource
    Detection of latent Epstein-Barr virus (EBV) DNA in paraffin sections of nasopharyngeal carcinomas expressing no EBV-encoded small RNAs using in situ PCR (1997)
    Springer
    Archives of virology 142 (1997), S. 1743-1756 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  In situ hybridization (ISH) with EBER 1 (Epstein-Barrvirus (EBV)-encoded small RNA1) probes is widely used for in situ detection of EBV-infected cells. ISH with an EBER1 probe showed that 10 of 40 NPC cases were negative for EBER1 expression. For in situ detection of EBV DNA, we used in situ PCR method which can detect one copy of EBV DNA per cell. Of the 10 EBER1-negative cases, three cases including one each of well- and poorly differentiated carcinomas and undifferentiated carcinoma were EBV DNA-positive by in situ PCR. The remaining seven were truly negative for the presence of EBV DNA. All the EBV genome-negative NPC cases examined here were histologically classified as poorly differentiated or undifferentiated carcinomas which are known to be closely associated with EBV, indicating the existence of EBV DNA-negative NPC cases, regardless of histological type or differentiation. These results indicate that there are EBV genome-positive NPC cases expressing no EBER1 and that in situ PCR can be suitable for in situ detection of EBV-infected cells, especially those expressing no EBER1 in paraffin sections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007050050194
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  • 5
    Electronic Resource
    Electronic Resource
    Limited axillary thoracotomy vs video-assisted thoracoscopic surgery for spontaneous pneumothorax (1998)
    Springer
    Surgical endoscopy and other interventional techniques 12 (1998), S. 1155-1158 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Spontaneous pneumothorax — Video-assisted thoracoscopic surgery — Axillary thoracotomy — Postoperative pneumothorax recurrence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Video-assisted thoracoscopic surgery (VATS) has been reported to have a higher pneumothorax recurrence rate than limited axillary thoracotomy (LAT). We investigated the cause of pneumothorax recurrence after VATS by comparing surgical results for VATS and LAT. Methods: Ninety-five patients with spontaneous pneumothorax underwent resection of pulmonary bullae by VATS (n= 51) or LAT (n= 44). Operating duration, bleeding during surgery, number of resected bullae, duration of postoperative chest tube drainage, postoperative hospital stay, postoperative complication, and pneumothorax recurrence were analyzed to compare VATS and LAT in a retrospective study. Results: The duration of surgery, postoperative chest tube drainage, and postoperative hospital stay was significantly shorter in VATS than in LAT cases (p 〈 0.0005 and p 〈 0.005). Bleeding during surgery was significantly less in VATS than in LAT cases (p 〈 0.005). Numbers of resected bullae were significantly lower in VATS (2.7 ± 2.1) than in LAT cases (3.9 ± 2.7) (p 〈 0.05). Postoperative pneumothorax recurrence was more frequent in VATS (13.7%) than in LAT cases (6.8%), but there was no significant difference. Conclusions: VATS has many advantages over LAT in treating spontaneous pneumothorax, although the pneumothorax recurrence rate in VATS cases was double that in LAT cases. The lower number of resected bullae in VATS than in LAT cases suggests that overlooking bullae in operation could be responsible for the high recurrence rate in VATS cases. We recommend additional pleurodesis in VATS for spontaneous pneumothorax to prevent postoperative pneumothorax recurrence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900805
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  • 6
    Electronic Resource
    Electronic Resource
    Identification of molecular markers associated with leptine production in a population of Solanum chacoense Bitter (1999)
    Springer
    Theoretical and applied genetics 98 (1999), S. 39-46 
    Details
    ISSN: 1432-2242
    Keywords: Key words Glycoalkaloids ; Potato ; Metabolic pathways ; RAPD ; Leptine ; Insect resistance ; Solanum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract   Solanum chacoense Bitter, a wild relative of the cultivated potato, produces several glycoalkaloids, including solanine, chaconine, and the leptines. The foliar-specific leptine glycoalkaloids are believed to confer resistance to the Colorado Potato Beetle (CPB). Using two bulked DNA samples composed of high- and low-percent leptine individuals from a segregating F1 population of S. chacoense, we have identified two molecular markers that are closely linked to high percent solanine+chaconine and, conversely, to nil/low percent leptine. One of these, a 1,500-bp RAPD product (UBC370-1500), had a recombination value of 3% in the F1 progeny, indicating tight linkage. UBC370-1500 mapped to the end of the short arm of potato chromosome 1, in the region of a previously mapped major QTL for solanidine, from a S. tuberosum (solanidine)×S. berthaultii (solasodine) cross. Taken together, these results suggest that either (1) a major locus determining solanidine accumulation in Solanum spp. is on chromosome 1 in the region defined by the RFLP markers TG24, CT197, and CT233, or (2) this region of chromosome 1 may harbor two or more important genes which determine accumulation of steroidal aglycones. These findings are important for the genetics of leptine (as well as other glycoalkaloid) accumulation and for the development of CPB-resistant potato varieties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220051037
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  • 7
    Electronic Resource
    Electronic Resource
    QTL mapping of foliar glycoalkaloid aglycones in Solanum tuberosum×S. berthaultii potato progenies: quantitative variation and plant secondary metabolism (1998)
    Springer
    Theoretical and applied genetics 97 (1998), S. 563-574 
    Details
    ISSN: 1432-2242
    Keywords: Key words Solasodine ; Solanidine ; Steroid alkaloid ; Restriction fragment length polymorphisms (RFLPs) ; Plant breeding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Glycoalkaloids are quantitatively inherited in Solanum, and in high concentrations they can be toxic to humans. The increased use of wild potato germplasm to improve the pest resistance, yield, and quality characteristics of cultivated potato may elevate or introduce new, more toxic glycoalkaloids into the cultivated gene pool. Therefore, it is important to increase our understanding of their inheritance, accumulation, and biosynthesis. Glycoalkaloids have two basic constituents – a glycosidic grouping and a steroid alkaloid skeleton. Steroid alkaloids are classified as solanidanes and spirosolanes, of which solanidine and solasodine are, respectively, representatives. RFLP-mapped, diploid, reciprocal backcross potato progenies involving the parents S. tuberosum and S. berthaultii, which produce solanidine and solasodine, respectively, were analyzed for segregation of the glycoalkaloids solanine, chaconine, solasodine and solamargine to identify quantitative trait loci (QTLs) for the production of the aglycones solanidine and solasodine. The F1 clone M200-30 exhibited low to nondetectable levels of solasodine and solanidine, suggesting that expression was controlled by recessive genes. In a backcross to berthaultii (BCB) and backcross to tuberosum (BCT), several QTLs for the accumulation of solasodine and solanidine were identified. Three QTLs explaining approximately 20% of the variation in solasodine were identified in BCB on chromosomes 4, 6, and 12. Similarly, three QTLs were identified in BCT on chromosomes 4, 8 and 11, but these accounted for only 10% of the variation observed in solasodine accumulation. Two QTLs for solanidine were identified in BCT on chromosomes 1 and 4. The QTL located on chromosome 1 was highly significant, accounting for 17% and 22% of the variation in solanidine accumulation in 1994 and 1995, respectively. This same QTL was also detected in BCB. The QTLs detected in this study probably represent structural and/or regulatory genes controlling the accumulation of solasodine and solanidine. Results are discussed in the context of steroid alkaloid accumulation and biosynthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050932
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  • 8
    Electronic Resource
    Electronic Resource
    Stability of the boundary layer on a sphere rotating in still fluid (1998)
    Springer
    Acta mechanica 129 (1998), S. 243-253 
    Details
    ISSN: 1619-6937
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary A theoretical study of the transition of a three-dimensional boundary layer on a sphere rotating in still fluid is carried out by a linear stability analysis. A set of perturbation equations governing the instability of the flow field is derived assuming the perturbations to be consisting of spiral vortices. It is shown that the critical Reynolds numbers obtained in the present analytical study are close to those observed in experiments. It has been found that the streamline-curvature instability appears in the rotating sphere flow. It is also shown that the cross-flow instability is dominant near the poles of a sphere while the streamline-curvature instability overtakes near the equator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01176749
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  • 9
    Electronic Resource
    Electronic Resource
    Equations with Singular Diffusivity (1999)
    Springer
    Journal of statistical physics 95 (1999), S. 1187-1220 
    Details
    ISSN: 1572-9613
    Keywords: singular diffusivity ; faceted growth ; grain boundary ; extended gradient system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Recently models of faceted crystal growth and of grain boundaries were proposed based on the gradient system with nondifferentiable energy. In this article, we study their most basic forms given by the equations u t=(u x/|u x|) x and u t=(1/a)(au x/|u x|) x , where both of the related energies include a |u x| term of power one which is nondifferentiable at u x=0. The first equation is spatially homogeneous, while the second one is spatially inhomogeneous when a depends on x. These equations naturally express nonlocal interactions through their singular diffusivities (infinitely large diffusion constant), which make the profiles of the solutions completely flat. The mathematical basis for justifying and analyzing these equations is explained, and theoretical and numerical approaches show how the solutions of the equations evolve.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004570921372
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