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  • 11
    Electronic Resource
    Electronic Resource
    Anterior urethral valve (1995)
    Springer
    Pediatric surgery international 10 (1995), S. 501-503 
    Details
    ISSN: 1437-9813
    Keywords: Valve ; Anterior urethral valve ; Urethral obstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case of an 11-year-old boy with an anterior urethral valve is reported. A weak urinary stream and urinary dribbling were his main symptoms. Clinical evaluation consisted of renal ultrasonography, an intravenous urogram, a voiding cystourethrogram, and panendoscopy. Transurethral excision of the valve achieved a satisfactory result.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00176399
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  • 12
    Electronic Resource
    Electronic Resource
    Dissection of Retroesophageal Aortic Diverticulum and Descending Aorta in a Patient with Right Aortic Arch: Magnetic Resonance Demonstration (1996)
    Springer
    CardioVascular & interventional radiology 19 (1996), S. 438 -441 
    Details
    ISSN: 1432-086X
    Keywords: Key words: Aorta/aortic arch anomaly—Aortic diverticulum—Dissection—Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An acute aortic dissection involved the retroesophageal aortic diverticulum (RAD) and descending thoracic aorta in a patient with right aortic arch. The RAD, which was separated into false and true lumens by an intimal flap—the classic diagnostic sign of aortic dissection—was overlooked on transesophageal echocardiography and computed tomography but was clearly depicted on magnetic resonance imaging (MRI). It was found that MRI can delineate the anatomy of a congenital arch anomaly complicated by great vessels disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002709900095
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  • 13
    Electronic Resource
    Electronic Resource
    A novel monooxygenase model compound: the oxidative demethylation of a macrocyclic bicopper(I) complex (1995)
    Springer
    Transition metal chemistry 20 (1995), S. 634-635 
    Details
    ISSN: 1572-901X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00136432
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  • 14
    Electronic Resource
    Electronic Resource
    A Compartmental Model for the Ocular Pharmacokinetics of Cyclosporine in Rabbits (1995)
    Springer
    Pharmaceutical research 12 (1995), S. 433-437 
    Details
    ISSN: 1573-904X
    Keywords: cyclosporine ; ocular pharmacokinetics ; compartment model ; eye
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Studies were conducted in rabbits to determine the ocular distribution and elimination of cyclosporine, with the objective of developing a comprehensive pharmacokinetic model. Following a bolus dose into the anterior chamber, drug levels were measured in the aqueous humor, cornea, iris/ciliary body, lens, sclera, and conjunctiva. Cyclosporine was rapidly eliminated from the aqueous, but drug levels in ocular tissues persisted for in excess of 48 hours, particularly in the cornea and iris/ciliary body. The terminal elimination half life from these tissues was 45 hr and 30 hr, respectively, providing evidence that these tissues could act as a reservoir for the drug. It was found that a compartmental model accurately described the experimental data. A single compartment was used for each of the tissues and fluids sampled, except for the cornea, which was subdivided into two compartments, representing its tissue and aqueous regions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1016268922035
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  • 15
    Electronic Resource
    Electronic Resource
    Ethanol-Induced Cell Death by Lipid Peroxidation in PC12 Cells (1997)
    Springer
    Neurochemical research 22 (1997), S. 1187-1192 
    Details
    ISSN: 1573-6903
    Keywords: Lipid Peroxidation ; ethanol ; Cis-Parinaric acid = fluorescent probe for lipid peroxidation ; Resveratrol = antioxidant from grapes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Free radical generation is hypothesized to be the cause of alcohol-induced tissue injury. Using fluorescent cis-parinaric acid and TBARS, lipid peroxidation was shown to be increased in the presence of trace amounts of free ferrous ion in PC12 cells. This increase in lipid peroxidation was enhanced by ethanol in a dose dependent manner and also correlated with loss of cell viability, as measured by increased release of lactate dehydrogenase (LDH). Resveratrol, a potent antioxidant, had a protective effect against lipid peroxidation and cell death. These findings strongly suggest that ethanol-induced tissue injury and cell death is a free radical mediated process, and may be important in alcohol-related premature aging and other degenerative diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021968526696
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  • 16
    Electronic Resource
    Electronic Resource
    Cigarette smoking, alcohol consumption and risk of nasopharyngeal carcinoma in Taiwan (1999)
    Springer
    Cancer causes & control 10 (1999), S. 201-207 
    Details
    ISSN: 1573-7225
    Keywords: alcohol consumption ; cigarette smoking ; nasopharyngeal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives: Nasopharyngeal carcinoma (NPC) is rare in most countries but occurs with relatively high frequency among southern Chinese populations throughout the world. A case-control study of NPC was conducted in Taiwan to investigate the importance of active and passive cigarette exposure and alcohol consumption as risk factors for this disease. Methods: 375 histologically confirmed incident NPC cases (99% response rate) were prospectively identified from two hospitals in Taipei between July 1991 and December 1994 and administered a detailed questionnaire. 327 healthy community controls individually matched to cases on sex, age and residence were selected (88% response rate). Results: After multivariate adjustment, the odds ratio (OR) and 95% confidence interval (CI) was 1.7 (1.1–2.9 with p = 0.03 for increasing dose-response) for those who smoked for 25 years compared with non-smokers. Passive smoking during childhood or adult life was not associated with an increased risk of disease. Alcohol consumption was not associated with NPC risk. The OR for subjects with 15 grams of ethanol per day compared to non-drinkers was 1.1 (95% CI = 0.7–1.7). Conclusions: Our results suggest that long term cigarette smoking is associated with NPC but that low level exposure to cigarette smoke via passive exposure and alcohol consumption are not associated with disease risk.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008893109257
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  • 17
    Electronic Resource
    Electronic Resource
    Circulating intercellular adhesion molecule-1 (ICAM-1) in patients with hepatolithiasis (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 1682-1686 
    Details
    ISSN: 1573-2568
    Keywords: intercellular adhesion molecule-1 ; hepatolithiasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We evaluated the role of circulating intercellular adhesion molecule-1 in the pathogenesis of hepatolithiasis. From December 1994 to May 1995, 40 patients with hepatolithiasis were included. All the patients met the following criteria: (1) presence of hepatolithiasis, (2) no obvious clinical evidence of an associated intrahepatic cholangiocarcinoma, (3) no clinical manifestation of cholangitis for at least 72 hr, (4) no immunomodulatory agents in the last three weeks, and (5) no blood transfusion in the last three weeks. Venous blood samples were collected both before surgery and at least three months after complete clearance of the stones, and the serum concentrations of circulating intercellular adhesion molecule-1 were measured with a sand-wich enzyme immunoassay method. Fifteen healthy subjects were used as a control group. Bile specimens routinely obtained during surgery were cultured for aerobes and anaerobes. The x-ray films of cholangiography were all reviewed in detail. The mean value (834±128 ng/ml) of circulating intercellular adhesion molecule-1 (ICAM-1) in the patient group before surgery was significantly higher than that (346±68 ng/ml) of the control group (P〈0.01). The mean value (677±139 ng/ml) of circulating ICAM-1 in the patient group at least three months after complete clearance of the stones was significantly lower than that (834±128 ng/ml) of the patients before surgery (P〈0.01), but this mean value (677±139 ng/ml) was still significantly higher than that (346±68 ng/ml) of the control group (P〈0.01). Bacteria was present in the bile of all patients. The total number of bacterial species was 135, and there were an average of 3.4 bacterial species cultured per patient. Intrahepatic stricture was demonstrated in cholangiography in 33 patients (82.5%). In addition to the high incidence of intrahepatic bile duct strictures and bile infection, a significant elevation in circulating intercellular adhesion molecule-1 (sICAM-1) was shown in patients with hepatolithiasis. Our preliminary results seem to be promising and the real role of sICAM-1 deserves further investigation and elucidation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02087925
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  • 18
    Electronic Resource
    Electronic Resource
    Composition and Microstructure Determination of the Syndiotactic Copolymer of para-Methylstyrene and Styrene by Pyrolysis Gas Chromatography (1999)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 22 (1999), S. 11-16 
    Details
    ISSN: 0935-6304
    Keywords: Pyrolysis gas chromatography ; microstructure determination ; syndiotactic copolymers ; styrenes ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: ---The composition and microstructure of syndiotactic para-methylstyrene/styrene copolymer was determined by a pyrolysis gas chromatography (Py-GC) method. This method uses the styrene and para-methylstyrene monomer peak intensities to determine the styrene and para-methylstyrene composition in the copolymer. The number average sequence length of styrene was calculated by using the triad peak intensities. Because of the low concentration of para-methylstyrene in the copolymer, the number average sequence length of para-methylstyrene was determined with formulas that incorporate the copolymer composition and the number average sequence length of styrene. The distribution of para-methylstyrene defined by the terms “percent of single units” and “percent of desired distribution” was calculated by the number average sequence of para-methylstyrene. This method has been tested with copolymers containing up to 24 mole% of para-methylstyrene. The composition results from Py-GC of para-methylstyrene and styrene copolymers used in this study were in excellent agreement with 1H-NMR results.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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