In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 99, No. 7 ( 1999-02-23), p. 903-908
Abstract:
Background —The de novo occurrence of sustained ventricular tachycardia (VT) after CABG has been described, but the incidence, mortality rate, long-term follow-up, and mechanism are not well defined. Methods and Results —This prospective study enrolled consecutive patients undergoing CABG at a single institution. Patients were followed up for the development of sustained VT, and a detailed analysis of clinical, angiographic, and surgical variables associated with the occurrence of VT was performed. A total of 382 patients participated, and 12 patients (3.1%) experienced ≥1 episode of sustained VT 4.1±4.8 days after CABG. In 11 of 12 patients, no postoperative complication explained the VT; 1 patient had a perioperative myocardial infarction. The in-hospital mortality rate was 25%. Patients with VT were more likely to have prior myocardial infarction (92% versus 50%, P 〈 0.01), severe congestive heart failure (56% versus 21%, P 〈 0.01), and ejection fraction 〈 0.40 (70% versus 29%, P 〈 0.01). When all 3 factors were present, the risk of VT was 30%, a 14-fold increase. Patients with VT had more noncollateralized totally occluded vessels on angiogram (1.4±0.97 versus 0.54±0.7, P 〈 0.01), a bypass graft across a noncollateralized occluded vessel (1.50±1.0 versus 0.42±0.62, P 〈 0.01), and a bypass graft across a noncollateralized occluded vessel to an infarct zone (1.50±1.0 versus 0.17±0.38, P 〈 0.01). By multivariate analysis, the number of bypass grafts across a noncollateralized occluded vessel to an infarct zone was the only independent factor predicting VT. Conclusions —The first presentation of sustained monomorphic VT in the recovery period after CABG is uncommon, but the incidence is high in specific clinical subsets. Placement of a bypass graft across a noncollateralized total occlusion in a vessel supplying an infarct zone was strongly and independently associated with the development of VT.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/01.CIR.99.7.903
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
1999
detail.hit.zdb_id:
1466401-X
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