GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Greenland under changing climates: sensitivity experiments with a new three-dimensional ice-sheet model
    International Glaciological Society ; 1995
    In:  Annals of Glaciology Vol. 21 ( 1995), p. 1-7
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 21 ( 1995), p. 1-7
    Abstract: A new three-dimensional, time-dependent ice-sheet model, including the calculation of the coupled temperature and velocity fields, isostatic adjustment of the bedrock and a mass-balance parameterization, was used to reconstruct the evolution of the Greenland ice sheet in response to a climate history derived from the oxygen-18 measured in the GRIP ice core. Steady-state experiments were done to test the sensitivity of the model, first to variations of poorly known parameters, secondly to different climates. These experiments show that the modelled ice sheet is not very sensitive to variations in the geothermal heat flux, but very sensitive to changes in the accumulation.
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.3189/S0260305500015512
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1995
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    A simplified multi-scale model for predicting climatic variations of the ice-sheet surface elevation in central Antarctica
    International Glaciological Society ; 1996
    In:  Annals of Glaciology Vol. 23 ( 1996), p. 28-35
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 23 ( 1996), p. 28-35
    Abstract: The equation describing the surface evolution of a large ice sheet is examined on the basis of a scale analysis applied to Antarctic conditions. Changes in the surface elevation are mainly driven by mass-balance fluctuations which approximately follow global atmospheric temperature variations. The essential spatial non-uniformity of the accumulation rate and the resultant difference between central and coastal regions in reaction time-scales are taken into account. The dynamic interaction of the time-lagging interior with the quasi-stationary margin is described. As a result, a simplified model is deduced to simulate the surface-elevation variations in the central parts of the Antarctic ice sheet caused by mass-balance perturbations corresponding to the main Milankovich cycles with the periods of 19–100 kyears. Special computational tests are performed to validate the model through intercomparison with the predictions obtained with a two-dimensional thermomechanical model. The sensitivity of the model to physical factors (represented by dimensionless tuning parameters) is discussed. Climatically controlled variations of the ice-sheet thickness in the vicinity of Vostok Station during the past 200 kyears are estimated.
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.1017/S0260305500013227
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1996
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    A thermomechanical model of ice-shelf flow
    International Glaciological Society ; 1996
    In:  Annals of Glaciology Vol. 23 ( 1996), p. 13-20
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 23 ( 1996), p. 13-20
    Abstract: An ice-shelf model which features efficient numerical techniques is developed to determine the back-force exerted by sides and pinning points, such as islands of an embayed ice shelf. The model is applied to three ideal geometries and shows that the restraint exerted by a small island, even far downstream from the grounding line, can represent about one-half of the total restraint due to the embayment. Our results are further interpreted to suggest several criteria useful for testing any ice-shelf model.
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.3189/S0260305500013203
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1996
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Cyclophosphamide, Doxorubicin, Vincristine, Prednisone Dose Intensification With Granulocyte Colony-Stimulating Factor Markedly Depletes Stem Cell Reserve for Autologous Bone Marrow Transplantation
    American Society of Hematology ; 1997
    In:  Blood Vol. 90, No. 12 ( 1997-12-15), p. 4996-5001
    Details
    In: Blood, American Society of Hematology, Vol. 90, No. 12 ( 1997-12-15), p. 4996-5001
    Abstract: Hematopoietic growth factors allow dose escalation of chemotherapy. This approach may potentially reduce the quality and quantity of hematopoietic stem cells. The capacity of stem cells recovered after dose intensification to support myeloablative therapy is unknown. In patients with previously untreated advanced follicular lymphoma, trilineage hematopoietic engraftment was compared in two sequential trials of induction therapy (standard dose cyclophosphamide, doxorubicin, vincristine, prednisone [CHOP] without growth factors or dose intensification CHOP supported by granulocyte colony-stimulating factor [G-CSF ] ) followed by identical myeloablative therapy and autologous stem cell support. Neutrophil, platelet, and red blood cell (RBC) engraftment were compared on days 100, 180, and 360 after stem cell reinfusion. Despite similar patient characteristics including reinfusion of comparable numbers of marrow mononuclear cells, after stem cell transplantation, a highly significant prolongation of neutrophil and platelet engraftment was seen in patients who received high dose CHOP and G-CSF in comparison to standard dose CHOP. These findings suggest that dose intensified chemotherapy and G-CSF recruited stem cells into a proliferative phase and that G-CSF allowed retreatment at a time when stem cells were susceptible to damage by cytotoxic therapy. Such inadequate hematologic engraftment after myeloablative therapy might be avoided by either shortening the time that growth factor support is administered, lengthening the interval between cycles, or attempting to repetitively harvest additional stem cells either from the marrow or peripheral blood. Therefore, intensification of chemotherapy with growth factor support must be used with caution if stem cells are to be used to support myeloablative therapy.
    Type of Medium: Online Resource
    ISSN: 1528-0020 , 0006-4971
    URL: Article
    DOI: 10.1182/blood.V90.12.4996
    RVK:
    XA 33000
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Hematology
    Publication Date: 1997
    detail.hit.zdb_id: 1468538-3
    detail.hit.zdb_id: 80069-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Cyclophosphamide, Doxorubicin, Vincristine, Prednisone Dose Intensification With Granulocyte Colony-Stimulating Factor Markedly Depletes Stem Cell Reserve for Autologous Bone Marrow Transplantation
    American Society of Hematology ; 1997
    In:  Blood Vol. 90, No. 12 ( 1997-12-15), p. 4996-5001
    Details
    In: Blood, American Society of Hematology, Vol. 90, No. 12 ( 1997-12-15), p. 4996-5001
    Abstract: Hematopoietic growth factors allow dose escalation of chemotherapy. This approach may potentially reduce the quality and quantity of hematopoietic stem cells. The capacity of stem cells recovered after dose intensification to support myeloablative therapy is unknown. In patients with previously untreated advanced follicular lymphoma, trilineage hematopoietic engraftment was compared in two sequential trials of induction therapy (standard dose cyclophosphamide, doxorubicin, vincristine, prednisone [CHOP] without growth factors or dose intensification CHOP supported by granulocyte colony-stimulating factor [G-CSF ] ) followed by identical myeloablative therapy and autologous stem cell support. Neutrophil, platelet, and red blood cell (RBC) engraftment were compared on days 100, 180, and 360 after stem cell reinfusion. Despite similar patient characteristics including reinfusion of comparable numbers of marrow mononuclear cells, after stem cell transplantation, a highly significant prolongation of neutrophil and platelet engraftment was seen in patients who received high dose CHOP and G-CSF in comparison to standard dose CHOP. These findings suggest that dose intensified chemotherapy and G-CSF recruited stem cells into a proliferative phase and that G-CSF allowed retreatment at a time when stem cells were susceptible to damage by cytotoxic therapy. Such inadequate hematologic engraftment after myeloablative therapy might be avoided by either shortening the time that growth factor support is administered, lengthening the interval between cycles, or attempting to repetitively harvest additional stem cells either from the marrow or peripheral blood. Therefore, intensification of chemotherapy with growth factor support must be used with caution if stem cells are to be used to support myeloablative therapy.
    Type of Medium: Online Resource
    ISSN: 1528-0020 , 0006-4971
    URL: Article
    DOI: 10.1182/blood.V90.12.4996.4996_4996_5001
    RVK:
    XA 33000
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Hematology
    Publication Date: 1997
    detail.hit.zdb_id: 1468538-3
    detail.hit.zdb_id: 80069-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Coupling an AGCM with an ISM to investigate the ice sheets mass balance at the Last Glacial Maximum
    American Geophysical Union (AGU) ; 1998
    In:  Geophysical Research Letters Vol. 25, No. 4 ( 1998-02-15), p. 531-534
    Details
    In: Geophysical Research Letters, American Geophysical Union (AGU), Vol. 25, No. 4 ( 1998-02-15), p. 531-534
    Type of Medium: Online Resource
    ISSN: 0094-8276
    URL: Article
    DOI: 10.1029/98GL00133
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 1998
    detail.hit.zdb_id: 2021599-X
    detail.hit.zdb_id: 7403-2
    SSG: 16,13
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Ice-sheet mass balance during the last glacial maximum
    International Glaciological Society ; 1997
    In:  Annals of Glaciology Vol. 25 ( 1997), p. 145-152
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 25 ( 1997), p. 145-152
    Abstract: In the framework of the Paleoclimate Modelling Intercomparison Project (PMIP), simulations of the Last Glacial Maximum (LGM) have- been performed. More than 10 different atmospheric general circulation models (AGCMs) have been used with the same boundary conditions: sea-surface temperatures prescribed by CLIMAP (1981), ice-sheet reconstruction provided by Peltier (1994), change in insolation, and reduced CO 2 content. One of the major questions is to investigate whether the simulations of the LGM are in equilibrium with the prescribed ice-sheet reconstruction. To answer this question, we have used two different approaches. First, we analyze the results of a sel of LGM simulations performed with different versions of the Laboratoire de Meteorolo-gie Dynamique (LMD) AGCM and study the hydrologic and snow- budgets over the Laurcntide and Fennoscandian ice sheets. Second, we use the AGCM outputs to force an ice-sheet model in order to investigate its ability to maintain the ice sheets as reconstructed by CLIMAP (1981) or Peltier (1994).
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.1017/S026030550001394X
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1997
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    A simplified multi-scale model for predicting climatic variations of the ice-sheet surface elevation in central Antarctica
    International Glaciological Society ; 1996
    In:  Annals of Glaciology Vol. 23 ( 1996), p. 28-35
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 23 ( 1996), p. 28-35
    Abstract: The equation describing the surface evolution of a large ice sheet is examined on the basis of a scale analysis applied to Antarctic conditions. Changes in the surface elevation are mainly driven by mass-balance fluctuations which approximately follow global atmospheric temperature variations. The essential spatial non-uniformity of the accumulation rate and the resultant difference between central and coastal regions in reaction time-scales are taken into account. The dynamic interaction of the time-lagging interior with the quasi-stationary margin is described. As a result, a simplified model is deduced to simulate the surface-elevation variations in the central parts of the Antarctic ice sheet caused by mass-balance perturbations corresponding to the main Milankovich cycles with the periods of 19–100 kyears. Special computational tests are performed to validate the model through intercomparison with the predictions obtained with a two-dimensional thermomechanical model. The sensitivity of the model to physical factors (represented by dimensionless tuning parameters) is discussed. Climatically controlled variations of the ice-sheet thickness in the vicinity of Vostok Station during the past 200 kyears are estimated.
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.3189/S0260305500013227
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1996
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Air content along the Greenland Ice Core Project core: A record of surface climatic parameters and elevation in central Greenland
    American Geophysical Union (AGU) ; 1997
    In:  Journal of Geophysical Research: Oceans Vol. 102, No. C12 ( 1997-11-30), p. 26607-26613
    Details
    In: Journal of Geophysical Research: Oceans, American Geophysical Union (AGU), Vol. 102, No. C12 ( 1997-11-30), p. 26607-26613
    Abstract: We present here measurements of the air content of the ice, V , performed along the Greenland Ice Core Project (GRIP) ice core. The main features of the long‐term trends are (1) a decrease of 13% between the last glacial maximum (LGM) and the earliest part of the Holocene, and (2) an increase of 8% during the Holocene. The resultsare discussed in terms of changes in atmospheric pressure, surface elevation and porosityat close‐off. The V record contains a significant signal of past changes of surface elevation in qualitative agreement with ice sheet modeling simulations. It suggests a thickening of central Greenland during the transition from the LGM to the early Holocene, and a significant thinning through the Holocene period. It also stresses the large influence on past V variations of changes in ice porosity, which are not explained by the present‐day spatial relationship with temperature and may reflect changes in other surface climatic parameters (like precipitation seasonality or wind stress). The potential role of temporalvariations of atmospheric pressure patterns is also evaluated. Air content results in the GRIP ice older than 110 ka indicate values approximately in the same range as those observed during the last 40,000 years, with generally higher air content corresponding to isotopically warmer ice.
    Type of Medium: Online Resource
    ISSN: 0148-0227
    URL: Article
    DOI: 10.1029/97JC01908
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 1997
    detail.hit.zdb_id: 2033040-6
    detail.hit.zdb_id: 3094104-0
    detail.hit.zdb_id: 2130824-X
    detail.hit.zdb_id: 2016813-5
    detail.hit.zdb_id: 2016810-X
    detail.hit.zdb_id: 2403298-0
    detail.hit.zdb_id: 2016800-7
    detail.hit.zdb_id: 161666-3
    detail.hit.zdb_id: 161667-5
    detail.hit.zdb_id: 2969341-X
    detail.hit.zdb_id: 161665-1
    detail.hit.zdb_id: 3094268-8
    detail.hit.zdb_id: 710256-2
    detail.hit.zdb_id: 2016804-4
    detail.hit.zdb_id: 3094181-7
    detail.hit.zdb_id: 3094219-6
    detail.hit.zdb_id: 3094167-2
    detail.hit.zdb_id: 2220777-6
    detail.hit.zdb_id: 3094197-0
    SSG: 16,13
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Greenland under changing climates: sensitivity experiments with a new three-dimensional ice-sheet model
    International Glaciological Society ; 1995
    In:  Annals of Glaciology Vol. 21 ( 1995), p. 1-7
    Details
    In: Annals of Glaciology, International Glaciological Society, Vol. 21 ( 1995), p. 1-7
    Abstract: A new three-dimensional, time-dependent ice-sheet model, including the calculation of the coupled temperature and velocity fields, isostatic adjustment of the bedrock and a mass-balance parameterization, was used to reconstruct the evolution of the Greenland ice sheet in response to a climate history derived from the oxygen-18 measured in the GRIP ice core. Steady-state experiments were done to test the sensitivity of the model, first to variations of poorly known parameters, secondly to different climates. These experiments show that the modelled ice sheet is not very sensitive to variations in the geothermal heat flux, but very sensitive to changes in the accumulation.
    Type of Medium: Online Resource
    ISSN: 0260-3055 , 1727-5644
    URL: Article
    DOI: 10.1017/S0260305500015512
    Language: English
    Publisher: International Glaciological Society
    Publication Date: 1995
    detail.hit.zdb_id: 2122400-6
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...