In:
Pediatric Anesthesia, Wiley, Vol. 5, No. 2 ( 1995-03), p. 115-119
Abstract:
In this study, we compared three gas compositions to determine if the duration of apnoea for S po 2 to decrease is proportionate to the oxygen fraction of the gas prior to apnoea. Twenty‐five patients ASA physical status 1–2 aged two months to 12 years were included in the study. Anaesthesia was induced via a mask with 5% sevoflurane and 66% N 2 O in oxygen. After paralysis with vecuronium (0.12 mg·kg −1 , i.v.) the trachea was intubated and anaesthesia was maintained with sevoflurane and N 2 O in oxygen. When cardiovascular stability was obtained, the patient was randomly set to breathe one of three gas compositions: 1. oxygen ( F io 2 1.0), 2. N 2 O/O 2 ( F io 2 0.4), and 3. air/O 2 ( F io 2 0.4). All three gas compositions included 2–4% of sevoflurane to maintain anaesthesia. After more than eight min of each gas breathing, apnoea was begun by disconnecting the breathing circuit from the tracheal tube. The time from the start of apnoea ( S po 2 100%) to S po 2 of 95% (T 95 ) was measured. T 95 measured after breathing N 2 O/O 2 and air/O 2 were 34.6 ± 5.7 and 28.8 ± 4.7% of that measured after oxygen breathing ( P 〈 0.001 vs oxygen breathing, P 〈 0.001 vs oxygen and N 2 O/O 2 breathing), respectively. Preoxygenation before intubation was validated to delay the haemoglobin desaturation brought about by apnoea. An induction technique using a low F io 2 will allow rapid haemoglobin desaturation.
Type of Medium:
Online Resource
ISSN:
1155-5645
,
1460-9592
DOI:
10.1111/pan.1995.5.issue-2
DOI:
10.1111/j.1460-9592.1995.tb00255.x
Language:
English
Publisher:
Wiley
Publication Date:
1995
detail.hit.zdb_id:
2008564-3
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