In:
FEBS Letters, Wiley, Vol. 158, No. 1 ( 1983-07-11), p. 139-142
Abstract:
Three acyclic derivatives (3,7‐dimethyl‐10‐ethyl‐2,4,6,8‐dodecatetraenal, 3,7,10‐trimethyl‐2,4,6,8‐dodecatetraenal, and 3,7,10‐trimethyl‐2,4,6,8‐undecatetraenal) have been synthesized and the 2‐ cis , 6‐ cis , 2,6‐di cis and all‐ trans isomers of each isolated. Unlike the undecatetraenal compound, the dodecatetraenal derivatives, have methyl groups which can mimic the C‐1 and/or C‐5 methyl group of retinal. The 6‐ cis and 2,6‐di cis isomers of the dodecatetraenal compounds form photosensitive pigments with bovine opsin. No pigment is obtained with the undecatetraenal derivative. Therefore, although the retinal cyclohexyl ring is not essential for pigment formation, at least one methyl group corresponding to the C‐1 or C‐5 retinal methyl may be required for obtaining stable opsin pigments.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(83)80694-2
Language:
English
Publisher:
Wiley
Publication Date:
1983
detail.hit.zdb_id:
1460391-3
SSG:
12
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