ISSN:
1573-3238
Keywords:
Molindone
;
neuroleptics
;
pregnancy
;
psychosis
;
antipsychotics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The onset of psychosis during pregnancy presents several difficult management decisions and a careful risk–benefit analysis is required. Withholding antipsychotic treatment may produce more risks than benefits. Studies on neuroleptic teratogenicity are contradictory. Most of the commonly used neuroleptics exhibit a pregnancy risk of category C. Neuroleptic use during pregnancy may be associated with adverse effects in the pre- and postnatal period. These concerns include compromising uterine blood flow, post-partum neonatal sedation, and extrapyramidal signs expressed in the neonate. Each neuroleptic exhibits a unique pharmacokinetic profile. The antipsychotic properties and side effects considered most significant include sedation, half-life, hypotension, and apparent hydrophilicity. In this case study a decision to select molindone was based on these parameters.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1026234125565
Permalink
