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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    CardioVascular & interventional radiology 18 (1995), S. 367-372 
    ISSN: 1432-086X
    Keywords: Superior vena cava syndrome ; Expandable metallic stents ; Venous occlusion ; Palliativetherapy ; Lung carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose To assess the use of percutaneous endovascular stent insertion in the management of superior vena cava (SVC) occlusion. Methods Percutaneous endovascular stent insertion was attempted in 13 patients, age range 20–72 (mean 55.5) years, with symptomatic total occlusion of the SVC. Twelve patients had known malignant disease of the thorax. The other patient (age 20) had chronic SVC obstruction, the cause of which was unknown at the time of the procedure. There was initial angiographic assessment and removal of thrombus by thrombolysis (10 patients) and/or clot aspiration (3 patients). Following successful lysis or aspiration, single or multiple endovascular stents were inserted. Results The inability to cross the lesion with a guidewire prevented stent insertion in 2 patients (15.4%). There was primary success in the remaining 11 patients (84.6%), with associated symptomatic relief. Some recurrence of symptoms occurred in 5 of the 11 patients (45.5%) after a time interval ranging from 14 to 183 days. In all cases of symptomatic recurrence, patency was reestablished with further thrombolysis and/or further stent insertion. All successfully treated patients have since died. All 11 patients remained symptomatically free of SVC occlusion until death, with postprocedure survival ranging from 5 to 243 days. Conclusion The percutaneous management of complete SVC occlusion with thrombolysis and/or clot aspiration followed by stent insertion is safe and effective, giving sustained symptomatic relief.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Glycoconjugate journal 13 (1996), S. 547-553 
    ISSN: 1573-4986
    Keywords: glycophospholipids ; ceramide-1-phosphate sugars ; azidosphingosine-1-phosphate sugars ; glycosyl phosphite ; glycosyl phosphate ; O-glycosyl trichloroacetimidate ; N-acetylneuraminic acid (Neu5Ac)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Ceramide-1-phosphate sugars were synthesized by direct glycosyl phosphite/phosphate andO-glycosyl trichloroacetimidate/phosphate exchange reactions, respectively. Thus, ceramide-1-O-phosphoric acid 5 gave with sialyl phosphite1 as sialyl donor directly β-linked sialyl phosphate6; deprotection afforded the corresponding glycophospholipid ceramide-1-phosphateN-acetylneuraminate7. Similarly, fromO-glucosyl- andO-galactosyltrichloroacetimidate10 and13 with phosphoric acid derivative5 glycosyl ceramide-1-phosphate sugars12 and15, respectively, were obtained.
    Type of Medium: Electronic Resource
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