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  • Bladder  (1)
  • Civil and Mechanical Engineering  (1)
  • 1995-1999  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 25 (1997), S. 291-298 
    ISSN: 1434-0879
    Keywords: Bladder ; Obstruction ; Stimulation ; Rabbit ; Function ; Work
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: To correlate pharmacologic changes that occur in the bladder after a partial outlet obstruction with the bladder's ability to perform work and empty. Methods: After 2 weeks of partial outlet obstruction, rabbit bladders were stimulated in vitro both isovolumetrically [field stimulation (FS)] and to empty (FS, bethanechol, and KCl). Results: The obstructed bladders were separated into two groups according to their ability to empty when stimulated with FS. Compensated bladders were those that could empty as much as controls. Decompensated bladders emptied significantly less than controls. With FS and bethanechol, the compensated obstructed bladders showed no difference from the control bladders in their ability to empty. In contrast, with Kcl, the compensated bladders generated significantly less pressure, performed less work, and emptied less than controls. When the decompensated bladders were stimulated with all three types of stimulation, all parameters, including emptying ability, were significantly decreased. Conclusions: The reduction in the response of compensated bladders to Kc1 stimulation suggested that the initial defects to the bladder after an outlet obstruction involved the interaction of smooth muscle proteins with calcium and ATP. In contrast, the response of decompensated bladders to all three forms of stimulation was equally reduced, suggesting that the degenerative processes were directly related to significant cellular damage to metabolic processes involved in energy synthesis, storage, and utilization.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 22 (1998), S. 621-653 
    ISSN: 0363-9061
    Keywords: state parameter ; stress-state relation ; constitutive modelling ; plasticity ; critical state ; sand and clay ; Engineering ; Civil and Mechanical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: The purpose of this paper is to present a simple, unified critical state constitutive model for both clay and sand. The model, called CASM (Clay And Sand Model), is formulated in terms of the state parameter that is defined as the vertical distance between current state (v, p′) and the critical state line in v-ln p′ space. The paper first shows that the standard Cam-clay models (i.e. the original and modified Cam-clay models) can be reformulated in terms of the state parameter. Although the standard Cam-clay models prove to be successful in modelling normally consolidated clays, it is well known that they cannot predict many important features of the behavior of sands and overconsolidated clays. By adopting a general stress ratio-state parameter relation to describe the state boundary surface of soils, it is shown that a simple, unified constitutive model (CASM) can be developed for both clay and sand. It is also demonstrated that the standard Cam-clay yield surfaces can be either recovered or approximated as special cases of the yield locus assumed in CASM.The main feature of the proposed model is that a single set of yield and plastic potential functions has been used to model the behaviour of clay and sand under both drained and undrained loading conditions. In addition, it is shown that the behaviour of overconsolidated clays can also be satisfactorily modelled. Simplicity is a major advantage of the present state parameter model, as only two new material constants need to be introduced when compared with the standard Cam-clay models. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
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