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  • 5-HT3 antagonists  (1)
  • air to solid ratio  (1)
  • 1995-1999  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The role of the 5-HT3 antagonists ondansetron and dolasetron in the control of delayed onset nausea and vomiting in patients receiving moderately emetogenic chemotherapy (1997)
    Springer
    Annals of oncology 8 (1997), S. 181-185 
    Details
    ISSN: 1569-8041
    Keywords: chemotherapy ; clinical trial ; emesis ; 5-HT3 antagonists
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: 5-HT3 antagonists are effective inreducing the acute nausea and vomiting caused by cancer chemotherapy. However,it is not clear whether continuing these agents beyond twenty four hours isuseful in controlling emesis on days two to seven after chemotherapy. Patients and methods: Four hundred seven patients receivingmoderately emetogenic chemotherapy who had been given dexamethasone 8 mg i.v.and either ondansetron 32 mg i.v. or dolasetron 2.4 mg/kg i.v. were randomizedto continue either an oral form of their 5-HT3 antagonist(ondansetron 8 mg b.i.d. or dolasetron 200 mg daily) plus dexamethasone 8 mgp.o. daily or dexamethasone alone for days two to seven. Endpoints assessedby self-report were: 1) complete control (no vomiting, no rescue medications,no missing data) of emesis; 2) nausea severity; and 3) quality-of-life asmeasured by the EORTC QLQ-C30. Results: Continuation of 5-HT3 antagonists improvedslightly, but not significantly, the complete control rate (47% vs.41%; P = 0.24 one-sided) after chemotherapy. However, mean nauseaseverity was significantly (P = 0.015 one sided) reduced (by 3 mm on a10 cm scale) on the combined arm. Minimal differences in quality of life wereobserved. Conclusion: The benefit of continuing 5-HT3antagonists beyond 24 hours is modest and the merits of routine use in thesecircumstances debatable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008247830641
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effect of air to solid ratio in the clarification of yeast by colloidal gas aphrons (1998)
    Chichester : Wiley-Blackwell
    Journal of Chemical Technology AND Biotechnology 71 (1998), S. 335-339 
    Details
    ISSN: 0268-2575
    Keywords: colloidal gas aphrons ; yeast ; flotation ; air to solid ratio ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: A study on the clarification of baker's yeast suspension by Colloidal Gas Aphrons (CGA) employing a cationic surfactant, benzyl-dimethyl-hexadecyl-ammonium chloride, is presented. The variables investigated were the CGA flowrate, air flowrate and the yeast concentration. A separation efficiency as high as 95% was achieved at the optimum conditions of air flowrate and feed concentration. The mechanism of particle-bubble attachment was identified and a simple model for the monolayer adsorption of yeast cells on the bubble surface derived. © 1998 SCI
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
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    Paper (German National Licenses)
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