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  • Wiley  (2)
  • 1995-1999  (2)
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  • Wiley  (2)
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  • 1995-1999  (2)
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  • 1
    Online Resource
    Online Resource
    Wiley ; 1997
    In:  Tropical Medicine & International Health Vol. 2, No. 10 ( 1997-10), p. 934-940
    In: Tropical Medicine & International Health, Wiley, Vol. 2, No. 10 ( 1997-10), p. 934-940
    Type of Medium: Online Resource
    ISSN: 1360-2276
    Language: English
    Publisher: Wiley
    Publication Date: 1997
    detail.hit.zdb_id: 2018112-7
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  • 2
    In: Mycoses, Wiley, Vol. 41, No. s2 ( 1998-10), p. 81-85
    Abstract: Zusammenfassung. Im Obduktionsgut der Berliner Charité, einem Großklinikum mit durchschnittlich 1500 Krankenhausbetten und medizinischer Maximalversorgung, wurden in der Zeit von 1970–1993 insgesamt 93 autoptisch gesicherte Endomykosen diagnostiziert: 51 Candidosen (54,8%), 34 Aspergillosen (36,6%), 5 Crytococcosen (5,4%) 1 Zygomykose, 1 Trichosporose und 1 Coccidioidomykose. Dies entsprach einem Anteil von 0,7% der 13 375 verstorbenen Obduzierten in dieser Zeit. Die Obduktionsfrequenz lag bei 85,3%. In 3770 Fällen (2418 Erwaehsene und 1352 Kinder) erfolgte eine Hirnsektion. Bei nur 6 von 28 Patienten (18 Erwachsene, 10 Kinder) mit histologisch gesicherter zerebraler Mykose (11 Candidosen [39,3%], 10 Aspergillosen [35,7%] , 5 Cryptococcosen [17,9%], 1 Trichosporose und 1 Coccidioidomykose) wurde eine adäquate klinische Verdachtsdiagnose gestellt. Etwa 80% der Mykosen des ZNS blieben somit zu Lebzeiten der Patienten unendeckt. Vor dem Hintergrund der weiter rückläufigen Obduktionsfrequenz in der Bundesrepublik Deutschland verlangen die in der vorliegenden Arbeit gemachten Beobachtungen nachhaltig die Erhöhung der Effizienz der mykologischen Lebzeitdiagnostik, in Klinik und Labor. Summary. From 1970 to 1993, a total of 93 endomycoses confirmed by post‐mortem examination was diagnosed in the autopsy material of the Berlin Charité, a large hospital with an average of 1,500 hospital beds and maximum medical care. These comprised 51 candidoses (54.8%), 24 aspergilloses (36.6%), five cryptococcoses (5.4%), one zygomycosis, 1 trichosporosis and one coccidioidomycoses. This corresponded to 0.7% of the 13,375 deceased persons autopsied during this period. The frequency of autopsy was 85.3%. In 3,770 cases (2,418 adults and 1,352 children), brain dissection was performed. An adequate clinical putative diagnosis was made in only six out of 28 patients (18 adults, 10 children) with histologically confirmed cerebral mycosis [11 candidoses (39.3%), 10 aspergilloses (35.7%), five cryptococcoses (17.9%), one trichosporosis and one coccidioidomycosis]. About 80% of the mycoses of the CNS thus remained undetected while the patients were alive. Against the background of the continuing reduction in the frequency of autopsy in the Federal Republic of Germany, the observations made in the present paper underscore the demand for improved efficiency of mycological in‐vivo diagnoses in the hospital and laboratory.
    Type of Medium: Online Resource
    ISSN: 0933-7407 , 1439-0507
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 1998
    detail.hit.zdb_id: 2020780-3
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