In:
Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 46, No. 3 ( 1998), p. 187-190
Abstract:
〈 b 〉 Objective: 〈 /b 〉 To identify the effect of the menstrual cycle and sex steroid hormone levels on insulin sensitivity in healthy women with non-insulin-dependent diabetic parents. 〈 b 〉 Methods: 〈 /b 〉 A clinical trial was realized in 6 healthy women with non-insulin-dependent diabetic parents and in 6 control subjects. In both phases of the menstrual cycle the following tests were made: insulin tolerance test, metabolic profile, and sex steroid hormone levels. 〈 b 〉 Results: 〈 /b 〉 Insulin sensitivity was significantly lower in the follicular (p = 0.004) and luteal (p = 0.01) phases of the menstrual cycle in probands compared with controls. In the luteal phase dehydroepiandrosterone was higher in probands than in controls (p = 0.009). 〈 b 〉 Conclusions: 〈 /b 〉 Healthy women with non-insulin-dependent diabetic parents had a lower insulin sensitivity in both phases of the menstrual cycle compared with the control group. Dehydroepiandrosterone was higher in the luteal phase in probands than controls.
Type of Medium:
Online Resource
ISSN:
0378-7346
,
1423-002X
Language:
English
Publisher:
S. Karger AG
Publication Date:
1998
detail.hit.zdb_id:
1482695-1
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