In:
Protein & Peptide Letters, Bentham Science Publishers Ltd., Vol. 5, No. 5 ( 1998-10), p. 251-256
Abstract:
The present study explores conditions to activate the carboxyl group before the coupling of C-terrninus-AA with TMS-ITC. N-tert-butoxy-carbonyl amino acids (Boc-AAs) and Leucine Enkephalin were used as models and isobutyl chloroformate was used as a C-terminal activator. The reaction coupling activated AA with TMS ITC was temperature dependent. We also·report here a new, efficient, economical and ecological technique to separate the mixture of amino acids thiohydantoins (TH-AA).
Type of Medium:
Online Resource
ISSN:
0929-8665
DOI:
10.2174/092986650505221111091512
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
1998
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