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  • Epistasis  (1)
  • Fluorescence  (1)
  • 1995-1999  (2)
  • 1945-1949
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 11 (1996), S. 237-246 
    ISSN: 1435-604X
    Keywords: Fluorescence ; Time-resolved confocal microscopy ; Porphyrins ; Fluorescence polarization ; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The application of a novel time-resolved confocal fluorescence microspectrometer to studies of the distribution and speciation of porphyrin photosensitizers in rat C6 cerebral glioma cells is described. The instrument combines a mode-locked argon ion laser excitation source with time-correlated single photon counting fluorescence detection and has sub-micron spatial and sub-nanosecond temporal resolution. The porphyrins studied were haematoporphyrin derivative (HpD), haematoporphyrin IX (HP), porphyrinc (Pc) and the tetrakiscarborane carboxylate ester of 2,4-(α,β-dihydroxyethyl) deuteroporphyrin IX (BOPP). From the heterogeneous emission observed in vitro, assignments and spatial location of various porphyrin species are proposed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 97 (1998), S. 502-506 
    ISSN: 1432-2242
    Keywords: Key words Additivity ; Diallel cross ; Dominance ; Epistasis ; Wheat ; Yellow rust
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Complete F1 and F2 diallel crosses were used to investigate the inheritance of yellow rust resistance among eight bread wheat lines, developed by CIMMYT for the East African Highlands, which showed a wide response to this disease. Both diallel sets were grown at a site with a high incidence of yellow rust, although for one season, during which the F1 diallel was grown, disease incidence was unusually low. Analyses disclosed the presence of additive, dominance and epistatic effects among those genes controlling rust resistance, with the former being the most important. At normal disease levels, excluding two arrays having resistant common parents removed non-allelic interactions from the F1 diallels. For all F2 diallels, and the remaining F1 diallel, omitting two arrays based on susceptible parents removed these interactions. Local selection of material from a broadly based germplasm appears to be a feasible method of developing adapted cultivars resistant to endemic diseases.
    Type of Medium: Electronic Resource
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