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  • Blackwell Publishing Ltd  (3)
  • 1995-1999  (3)
  • 1955-1959
  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To identify counselling requirements, we reviewed the frequency and type of non-trisomy 21 chromosome abnormalities found at amniocentesis after maternal serum screening for Down's syndrome.Design The study involved a review of the cytogenetic results of amniocenteses performed because of a raised maternal serum screening risk.Setting The maternal serum screening and amniocenteses were performed at hospitals in the Yorkshire region.Sample 1715 amniocenteses were performed as a result of a raised maternal serum screening risk for the period 1990 to 1993.Methods The cytogenetic results were classified into the main categories of numerical and structural chromosomal abnormalities.Main outcome measures The nature and frequency of abnormal cytogenetic results were identified in which parental samples were required in order to determine if the abnormal finding was de novo or familial and/or for which specialist genetic counselling was required.Results Sixty-nine pregnancies of 1715 amniocenteses were identified with a chromosomal abnormality (4.0%): 35 (2.0%) with trisomy 21 and 34 (2.0%) with another chromosomal abnormality. For 20 of these 34 abnormalities, parental karyotypes were required and in 29 of the 34 specialist genetic counselling was required.Conclusions Women undergoing maternal serum screening and, in particular, those proceeding to amniocentesis, should be informed that there is an equal chance that a chromosomal abnormality other than trisomy 21 will be found at amniocentesis, the nature of which usually requires parental samples and specialist counselling.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract In the present study, a total of 619 subgingival and extracrevicular samples from 66 early-onset periodontitis, 42 adult periodontitis/gingivitis and 36 treated Actinobacillus actinomycetemcomitans-associated periodontitis patients were selectively cultivated for presence of A. actinomycetemcomitans. The organism was recovered from 68% cases with early-onset periodontitis, 24% cases with adult periodontitis/gingivitis and 50% of treated patients. Associations between recovery from pooled subgingival plaque and samples from extracrevicular locations as well as between different extracrevicular samples, were not heterogeneous with regard to different groups with the exception for cheek/saliva comparisons (odds ratios: early-onset periodontitis 825; adult periodontitis 8.1; treated patients 117; 0.05〈p〈0.1). For associations between recovery of A. actinomycetemcomitans from pooled subgingival plaque/extracrevicular samples, Mantel-Haenszel's odds ratios of between 12.2 and 21.6 were calculated (p〈0.0001). The organism was isolated from 17 cheek mucosa samples of 18 patients identified as still harboring the organism after therapy. Present results point to the considerable value of cheek mucosa samples especially in treated patients to diagnose persistent A. actinomycetemcomitans colonization of the oral cavity.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Feeding intensity by whitefish Coregonus sp., in oligotrophic Lake Lucerne in Switzerland was high during dusk when the bulk of potential prey items were in the depth zone occupied by the fish. Diet composition was fairly uniform throughout the day but changed substantially over the seasons. The fish fed opportunistically; differences between seasons reflected changes in prey availability. During the intensive feeding and growing period (May-September), fish were found in the upper 20 m of the lake feeding primarily on cladocerans. Large and non-evasive species, Daphnia spp. and Bythotrephes longimanus, were the most numerous and frequent organisms in the diet during the major part of the growing season. Smaller (Bosmina spp.) as well as evasive species (cyclopoid copepods) were consumed in large numbers when larger, non-evasive species were rare in the lake. The fish showed strong preference for the least abundant crustacean, B. longimanus, while the most abundant crustaceans, calanoid copepods, were rare in the diet. The fish not only selected particular species but, within each species, selected the larger individuals. Diel vertical migration of the prey items in this lake could be, at least in part, attributed to fish predation pressure. The observed selectivity patterns shown by the fish are explained in terms of prey visibility, escape ability, the overlap in distribution of predators and prey in time and space, the profitability of the prey and the present trophic state of the lake.
    Type of Medium: Electronic Resource
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