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  • Chemistry  (27)
  • Human  (2)
  • Lens  (2)
  • 1995-1999  (15)
  • 1965-1969  (16)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 389-391 
    ISSN: 1432-1076
    Keywords: Sorbitol dehydrogenase ; Lens ; Congenital cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Lens sorbitol dehydrogenase activity was assayed in patients with congenital cataracts, senile cataracts, without cataracts and in one fetal lens. In patients with congenital cataracts we did not observe any abnormality of galactose and sorbitol metabolising enzymes in erythrocytes. In one of these patients with inexplicable congenital cataracts lens sorbitol dehydrogenase deficiency was found. Conclusion Determination of galactose metabolising enzymes, sorbitol dehydrogenase and polyols in lenses may help in understanding the mechanism of formation of inexplicable congenital cataracts.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 389-391 
    ISSN: 1432-1076
    Keywords: Key words Sorbitol dehydrogenase ; Lens ; Congenital cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Lens sorbitol dehydrogenase activity was assayed in patients with congenital cataracts, senile cataracts, without cataracts and in one fetal lens. In patients with congenital cataracts we did not observe any abnormality of galactose and sorbitol metabolising enzymes in erythrocytes. In one of these patients with inexplicable congenital cataracts lens sorbitol dehydrogenase deficiency was found. Conclusion Determination of galactose metabolising enzymes, sorbitol dehydrogenase and polyols in lenses may help in understanding the mechanism of formation of inexplicable congenital cataracts.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0878
    Keywords: Key words: Elastic fibres ; Placental stem villi ; Extravascular smooth muscle cells ; Adhesion plaques ; Talin immunoreactivity ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The stroma of human placental stem villi is believed to consist only of reticular and collagen fibres. In the present study we were able to show for the first time by light (orcein staining) and electron microscopy large amounts of elastic fibres in the stem villous stroma. Electron microscopically, homogeneous elastin was found alone or in association with microfibrils. In addition, microfibrils were observed forming long bands. These three structures, generally known to form elastic connective tissue, were seen in close connection with placental extravascular smooth muscle cells, which belong to the perivascular contractile sheath (PVCS) of stem villi. Elastin was associated with these smooth muscle cells and connected to collagen fibres via microfibrils. Collagen fibres were additionally interconnected by spike-like structures. Extravascular smooth muscle cells revealed numerous adhesion plaques which occupied conspicuously long cytoplasmic faces of the plasma membrane. In cryostat sections, immunoreactivity of talin, an attachment protein of adhesion plaques linking intracellular α-actin filaments with extracellular fibronectin, was detected in extravascular and vascular (media) smooth muscle cells. The arrangement of placental extravascular smooth muscle cells, elastic and collagen fibres suggests a functional myofibroelastic unit within the PVCS, which surrounds the large foetal blood vessels possibly contributing to elasticity and supporting tensile and/or contracting forces within the stem villi.
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  • 4
    ISSN: 1432-0878
    Keywords: Key words: Placental stem villi ; Perivascular contractile sheath ; Molecules of adhesion plaques ; Extracellular matrix molecules ; Immunocytochemistry ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. In previous studies, we have shown that smooth muscle cells and myofibroblast subpopulations of the perivascular stem villous sheath of the human placenta contain focal adhesion plaques and talin immunoreactivity. The close association of these cells to elastic and collagen fibres have led to the assumption of a functional myofibroelastic unit within the perivascular stem villous sheath. Interactions between the extracellular matrix and smooth muscle cells depend on a variety of structural protein assemblies. In the present study, we examined, by immunocytochemistry, whether the molecular assembly of extracellular matrix proteins and molecules of focal adhesions, known to be essential for signal transduction in smooth muscle cells, are also found in smooth muscle cells of the perivascular stem villous sheath of the human placenta. Vascular and extravascular smooth muscle cells were immunoreactive for α-actinin, vinculin, paxillin and tensin, the integrin chains α1 and β1, and the basement membrane components laminin and heparan/-chondroitin sulfate proteoglycan perlecan. pp125FAK did not react. In the extracellular matrix of blood vessel walls and the perivascular stem villous sheath, we found immunoreactivity of fibronectin and collagen types I, VI and undulin (collagen type XIV). From our data we conclude that within the perivascular stem villous sheath, there exists a system of signal transduction molecules, indicating a cross talk between the smooth muscle cells of this sheath and their surrounding extracellular matrix.
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 98 (1965), S. 1981-1987 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Tris(dimethylamino)-phosphan addiert Halogene (Cl2, Br2, J2) zu Tris(dimethylamino)-halogeno-phosphonium-halogeniden. Einige ihrer Eigenschaften werden beschrieben.
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 20 (1997), S. 85-93 
    ISSN: 0935-6304
    Keywords: Capillary gas chromatography ; Modified cyclodextrin phases ; Chiral organochlorines ; Biological samples ; Enantiomeric ratios ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Four chiral stationary phases containing modified cyclodextrines diluted in or chemically bonded to a non-chiral phase were used to resolve chiral organochlorine compounds such as α-hexachlorocyclohexane (α-HCH), perdeuterated α-HCH (α-PDHCH), β-and γ-pentachlorocyclohexene (PCCH), oxychlordane, cis-and trans-chlor- dane, cis- and trans-heptachlorepoxide, PCB 95, PCB 132, PCB 149, and Chiral tozaphenes.The elution order was determined by analyzing standards with known enantiomeric excesses.Furthermore, an internal standard was used to even out slight variations in the ratio of peak hights of enantiomers which were determined from injection to injection.None of the chiral stationary phases resolved all chiral organochlorine compounds. However, the β-TBDM(35% heptakis (6-O-t-butyldimethylsilyl-2,3-di-O-methyl)-β-cyclodextrin in OV 1701) column allowed the separation of all compounds under investigation except for PCB 95 and chiral toxaphenes.Emphasis was placed on the separation of as many as possible enantiomers on a chiral phase by application of one temperature program and with respect to unambiguous quantitation of biological samples such as bludder and liver of marine and terrestrial mammals.
    Additional Material: 7 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 18 (1995), S. 643-646 
    ISSN: 0935-6304
    Keywords: Gas chromatography/Mass spectrometry ; Chiral GC ; Deuterium-labeled compounds ; Hexachlorocyclohexane ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Perdeuterated α-1,2,3,4,5,6-hexachlorocyclohexane (α-PDHCH) was synthesized and isolated in pure form. α-PDHCH was baseline separated from unlabeled α-HCH by high resolution gas chromatography on different stationary phases. α-PDHCH was also resolved into its enantiomeric forms by application of a chiral GC phase. Furthermore, chiral chromatography of a mixture of labeled α-PDHDH and unlabeled α-HCH resulted in four peaks. Standard solutions of α-PDHCH are recommended both as recovery standard for sample clean-up and as internal standard for the quantitation of chlorinated hydrocarbons with GC/MS or GC/ECD in environmental samples.
    Additional Material: 4 Ill.
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  • 8
    ISSN: 1022-1336
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The porous copolymer films of N-methacryloyl-L-alanine methyl ester and diethyleneglycol-bis-allylcarbonate (diallyl oxydiethylene dicarbonate) were hydrolyzed with 1 M NaOH solution for 40 min at 25°C. The pores of the films showed pH response in diameter. The pore diameter of 3,7 μm in the buffer solution of pH 3 was closed completely at pH 5.
    Additional Material: 4 Ill.
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  • 9
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Schwellende Innendruckbeanspruchungen treten in Behältern, Reaktoren, Rohrleitungen, Armaturen, Pumpen und Verdichtern auf. Bei Apparaten wird die schwellende Beanspruchung oft nur durch die Inbetriebnahme und den Abschaltvorgang verursacht, so daß die Lastspielzahl innerhalb der Lebenszeit des Bauteils klein ist. In diesen Fällen werden die Bauteile nach der Zeitfestigkeit ausgelegt. Bei Pumpen und Verdichtern jedoch ist die Lastspielzahl sehr hoch, so daß, abgesehen von wenigen Ausnahmen, eine Auslegung auf Dauerfestigkeit erforderlich ist. Die Bauteile des Pumpen- und Verdichterbaues, welche im Dauerbetrieb durch schwellenden Innendruck belastet sind, sowie die dafür verwendeten Werkstoffe werden auf den Hochdruckmaschinenbau abgestimmt, weshalb nur verhältnismäßig dickwandige Bauteile behandelt werden. Es werden Versuchsergebnisse mitgeteilt und Hinweise für die Auslegung, die Wahl des Werkstoffes und die Oberflächenbehandlung gegeben.
    Additional Material: 11 Ill.
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  • 10
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An einer Kolbenpumpe mit Acrylglas-Zylinder wird das Verhalten der Ventile ohne Kavitation und bei verschiedener Stärke der Dampfblasenbildung beobachtet und anhand von Ventilhub- und Druckabfallkurven diskutiert. Die Ergebnisse werden mit stationären Messungen verglichen. Es zeigt sich, daß bei nichtkavitierendem Pumpenbetrieb der Druckabfall im Saugventil aus den bei stationärer Strömung gemessenen Verlustbeiwerten ζv = f (Re) berechnet werden kann. Abschließend werden die Auswirkungen verschiedener Kavitationszustände auf das Betriebsverhalten der Pumpe beschrieben und Maßnahmen zur Vermeidung schädlicher Kavitation genannt.
    Additional Material: 14 Ill.
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