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  • 1
    Electronic Resource
    Electronic Resource
    The distribution of Lewy bodies in pure autonomic failure: autopsy findings and review of the literature (1997)
    Springer
    Acta neuropathologica 94 (1997), S. 192-196 
    Details
    ISSN: 1432-0533
    Keywords: Key words Pure autonomic failure ; Lewy bodies ; Autopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pure autonomic failure (PAF; also known as idiopathic orthostatic hypotension or Bradbury-Eggleston syndrome) is an uncommon sporadic disorder, characterized by autonomic failure without other neurological deficits and histopathologically by cell loss in intermediolateral columns and sympathetic ganglia. Few postmortem studies of patients with PAF have been reported in the literature, and none have demonstrated Lewy bodies in distal axons, although this has been described as a feature in Parkinson’s disease with autonomic failure. We report a patient with PAF who had orthostatic hypotension and urinary symptoms for 15 years prior to death at the age of 63 years. Postmortem findings included typical and atypical Lewy bodies in the substantia nigra, locus ceruleus, substantia innominata, and sympathetic ganglia, as well as in autonomic axons in the epicardial fat, autonomic nerve fascicles in periadrenal adipose tissue, and autonomic nerves in the muscularis of the urinary bladder. Sites of autonomic nerve involvement correlated with clinical symptomatology, and thus were a valuable observation in the complete autopsy. Systemic autopsy results should be reviewed carefully in patients with PAF, as Lewy bodies in this disease may be seen in distal axons at a great length from their primary cell bodies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050693
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  • 2
    Electronic Resource
    Electronic Resource
    Monolithische filter (1972)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 23 (1972), S. 167-167 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01593225
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  • 3
    Electronic Resource
    Electronic Resource
    Die mechanische Kopplung im monolithischen Filter (1972)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 23 (1972), S. 1023-1023 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01596242
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  • 4
    Electronic Resource
    Electronic Resource
    The linear amino acid sequence α1 acid glycoprotein (1972)
    Springer
    Cellular and molecular life sciences 28 (1972), S. 24-25 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es gelang, die lineare Aminosäuresequenz von saurem α1-Glykoprotein (Orosomucoid), einem Globulin des menschlichen Plasmas, aufzuklären.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01928240
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  • 5
    Electronic Resource
    Electronic Resource
    MRI examination and monitoring of pediatric patients under sedation (1996)
    Springer
    Pediatric radiology 26 (1996), S. 280-281 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From April 1992 to May 1994, 780 patients aged from 1 day to 8 years were examined. Sedation of these patients was conducted by giving chlorprothixene orally and, in some cases, chloral hydrate had to be added. The patients were monitored with a pulse oxymeter. Investigations could begin after 50–120 min. In 710 patients (91 %) the first attempt to perform the examination was successful; 70 patients required one or two further attempts. Only two of the 780 patients (0.5 %) showed evidence of respiratory depression. The total number of pediatric MRI examinations performed in 1 year is almost 1000. In the hands of an experienced pediatric radiologist these examinations can be performed entirely without anesthesia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01372113
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  • 6
    Electronic Resource
    Electronic Resource
    Electron–Phonon Interaction and Optical Spectra of Metals (1998)
    Springer
    Journal of superconductivity 11 (1998), S. 755-768 
    Details
    ISSN: 1572-9605
    Keywords: Optical properties ; electron–phonon interaction ; high-T c superconductors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract Observed optical reflectivity in the infrared spectral region is compared with theoretical predictions in a strongly coupled electron–phonon system. Starting from a Fröhlich Hamiltonian, the spectral functions and their temperature dependence are derived. A full analysis including vertex corrections leads to an expression for the optical conductivity σ(ω) that can be formulated in terms of the well-known optical conductivity for a quasi-isotropic system without vertex corrections. A numerical comparison between the full result and the so-called extended Drude formula, its weak coupling expansion, shows little difference over a wide range of coupling constants. Normal-state optical spectra for the high-T c superconductors YBa2Cu3O7 and La2 − x Sr x CuO4 at optimal doping are compared with the results of model calculations. Taking the plasma frequency and ∈∞ from band structure calculations, the model has only one free parameter, the electron–phonon coupling constant λ. In both materials the overall behavior of the reflectivity can be well accounted for over a wide frequency range. Systematic differences exist only in the mid-infrared region. They become more pronounced with increasing frequency, which indicates that a detailed model for the optical response should include temperature-dependent mid-infrared bands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1022601409015
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  • 7
    Electronic Resource
    Electronic Resource
    126. Probleme mit künstlichen Receptoren zur Langzeitsteuerung biologischer Funktionsabläufe (1971)
    Springer
    Langenbeck's archives of surgery 329 (1971), S. 385-385 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01770545
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  • 8
    Electronic Resource
    Electronic Resource
    Über die Wirkung eines akuten Sauerstoffmangels auf den intraocularen Druck (1971)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 182 (1971), S. 147-153 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 10 gesunde Studenten atmeten 15% iges O2-Luftgemisch über 15 min. Vor, während und nach der Testperiode wurden Atemminuten-Volumen endexspiratorische O2- und CO2-Drucke, Blutgasdrucke (O2 und CO2) und die „oculäre Tension“ gemessen. Unter dieser Versuchsbedingung kam es zu keiner signifikanten Änderung der „oculären Tension“, wenn die im Leerversuch beobachteten Ergebnisse berücksichtigt werden. Auch 15 min nach Beendigung der Hypoxie zeigten sich keine signifikanten Veränderungen gegen-über den Ruheausgangswerten.
    Notes: Summary In 10 healthy students the effects of acute hypoxia on ventilation parameters, blood gas pressures (O2 and CO2) and ocular tension were studied. The kypoxia was obtained by breathing an air mixture of 15% oxygen. All values were registered simultaneously. During and after 15 min test period there was no significant change of ocular tension if the results of the control experiments are taken into consideration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00413236
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  • 9
    Electronic Resource
    Electronic Resource
    Quantitative Messung der Durchblutungsgröße des Auges (1973)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 186 (1973), S. 181-190 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Über Größe und Regulation der Durchblutung des Auges und seiner einzelnen Kreislaufcompartments liegen aus methodischen Gründen bisher kaum zuverlässige Daten vor. Die Partikelverteilungsmethode wird deshalb dazu benutzt, am Katzen- und Hundeauge die Durchblutungsgröße quantitativ zu bestimmen. Ergebnisse: 1. Katzen. Bei einem mittleren arteriellen Druck von 138 mm Hg, einem Herzzeitvolumen von 274,0 ml/min wurde eine mittlere Augendurchblutung von 1,1 ml/min gemessen (n=8). Die Durchblutungsgröße lag zwischen 0,36 ml/min bei einem PaCO2 von 22 mm Hg und 2,30 ml/min bei einem PaCO2 von 42 mm Hg. 2. Hunde. Bei einem mittleren arteriellen Druck von 90 mm Hg, einem Herzzeitvolumen von 1380,0 ml/min ergab sich eine mittlere Durchblutung des Gesamtauges von 0,86 ml/min (auf der Seite der Carotisligatur) bzw. 1,20 ml/min (auf der contralateralen Seite) (n=7). Die Durchblutungsgröße lag zwischen 0,30 ml/min bei einem PaCO2 von 28 mm Hg und 1,86 ml/min bei einem PaCO2 von 42 mm Hg. Die Durchblutung der tunica externa betrug durchschnittlich 4,3 ml/100 g min, der uvea und retina 209,8 ml/100 g min. Die Augendurchblutung zeigt eine deutliche Abhängigkeit vom arteriellen Kohlensäurepartialdruck.
    Notes: Summary Up to now there are very few data available about the flow volume and regulating mechanism of the blood circulation in the eye and its individual circulation compartments, which might be due to the methods used. In our investigations the particle distribution method was tested as a means for quantitative measurements of the flow volume, and was applied to the eyes of cats and dogs. Results: 1. Cats. At a mean arterial pressure of 138 mm Hg, and a cardiac output of 274.0 ml/min, mean blood circulation in the eye was between 1.1 ml/min (n=8). Flow volume was 0.36 ml/min with PaCO2 being 22 mm Hg, and 2.30 ml/min with PaCO2 being 42 mm Hg. 2. Dogs. At a mean arterial pressure of 90 mm Hg, and a cardiac output of 1380.0 ml/min, mean circulation in the whole globe was 0.86 ml/min (at the side of the carotid ligature) and 1.20 ml/min (at the contralateral side) respectively (n=7). Flow volume measured was 0.30 ml/min with PaCO2 being 28 mm Hg and 1.86 ml/min with PaCO2 being 42 mm Hg. Measurements of the circulation in the tunica externa gave a mean value of 4.3 ml/100 g min, those of uvea and retina 209.8 ml/100 g min. Blood flow in the eye shows a significant dependence on the arterial CO2 partial pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00407815
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  • 10
    Electronic Resource
    Electronic Resource
    Das Verhalten von Augentension und Rigiditäts-Koeffizient während Vergrößerung des funktionellen Totraums (1973)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 186 (1973), S. 191-202 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eigene Untersuchungen am Menschen hatten früher gezeigt, daß experimentelle Veränderungen der arteriellen Kohlensäurespannung gleichsinnige Änderungen der oculären Tension zur Folge hatten. Der Einfluß des arteriellen Sauerstoffpartialdrucks blieb unklar. Die vorliegende Untersuchung zeigt das Verhalten der oculären Tension und des Rigiditätskoeffizienten bei vergrößertem funktionellem Totraum, also Erhöhung des PaCO2 und Erniedrigung des PaO2. Beim Übergang von Normoventilation auf Versuchsbedingung änderten sich der arterielle Blutdruck von 130/70 auf 145/80, die Pulsfrequenz von 77/min auf 88/min, das AMV von 6,9 l/min auf 26,9 l/min, der PaO2 von 105,7 mmHg auf 74,0 mmHg, der PaCO2 von 34,5 mmHg auf 45,4 mmHg, die oculäre Tension von 7,0 Schiøtz-Einheiten auf 6,0 und der Rigiditätskoeffizient von 0,023 auf 0,015. Dieses Verhalten der verschiedenen Parameter wurde durch einen Selbstversuch unter höherer Belastung bestätigt. Die Untersuchungen zeigen, daß Änderungen des PaCO2 mit gleichsinnigen Änderungen der oculären Tension einhergehen, deren Ausmaß von der Höhe des PaO2 moduliert wird.
    Notes: Summary In former investigations on human eyes the authors had been able to show that experimental changes of the arterial CO2 tension caused similar changes of the ocular tension. The influence of the arterial O2 partial pressure could not be determined. In the present case the reactions of the ocular tension and of the coefficient of rigidity to an experimentally enlarged functional dead — space is investigated, as well as the increase in PaCO2 and the decrease in PaO2. While proceeding from normal ventilation to test conditions the following changes took place: Arterial blood pressure from 130/70 to 145/80, pulse frequence from 77/min to 88/min, TV from 6.9 l/min to 26.9 l/min (TV=tidal volume), PaO2 from 105.7 mmHg to 74.0 mmHg, PaCO2 from 34.5 mmHg to 45.4 mmHg, ocular tension from 7.0 Schiøtz units to 6.0, coefficient of rigidity from 0.023 to 0.015. These reactions of the different parameters could be verified under even stronger conditions with one of the authors as a test person. Investigations showed that changes of the PaCO2 coincide with similar changes of the ocular tension. The extend of these changes is modulated by the degree of the PaO2.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00407816
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