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  • Industrial Chemistry  (7)
  • Captopril  (2)
  • 1995-1999  (3)
  • 1985-1989  (3)
  • 1965-1969  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 64 (1986), S. 327-332 
    ISSN: 1432-1440
    Keywords: Severe hypertension ; Minoxidil ; Captopril
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The antihypertensive efficacy of minoxidil and captopril was compared in 23 males with essential or renal parenchymatous hypertension refractory to conventional antihypertensive drug therapy. Following a pretreatment period the patients were randomly assigned to receive either minoxidil, 2.5 mg twice daily (n=12), or captopril, 25 mg twice daily (n=11). In patients with diastolic blood pressure 〉95 mmHg, doses of minoxidil and captopril were increased in 2-week intervals. Patients who maintained diastolic pressure 〉95 mmHg and/or those with intolerable side effects were switched over to the alternative substance. After a mean observation period of 12 weeks a significant decrease in systolic and diastolic blood pressure was observed (179/114 vs 148/92 mmHg in the minoxidil group; 176/111 vs 158/97 mmHg in the captopril group). The primary response rate was 75% in patients treated with minoxidil and 55% in those with captopril (not significant). After the change to the alternative substance two of the four non-responders on captopril and one of the two non-responders on minoxidil became responders. Side effects occurred significantly more often during minoxidil than captopril (p〈0.05). The high efficacy of minoxidil and captopril in the treatment of severe hypertension refractory to conventional drugs was confirmed. Minoxidil lowered blood pressure slightly more than captopril, but it had a higher incidence of side effects than captopril.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 63 (1985), S. 361-363 
    ISSN: 1432-1440
    Keywords: Primary aldosteronism ; Captopril ; Spironolactone ; Renin-angiotensin ; Converting-enzyme ; Secondary hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In three patients with primary aldosteronism, the acute effect of a single dose of captopril on the elevated mean arterial blood pressure (MAP) was studied before and after 4 weeks of treatment with spironolactone. Before spironolactone therapy, captopril did not cause any drop in MAP. Four weeks later, after an oral daily dose of 400 mg spironolactone, MAP was still elevated in all three patients, though electrolyte abnormalities were fully corrected. Since plasma renin activity (PRA) was increased to values above the normal range, the acute effect of captopril on MAP was tested again. A single dose of 25 mg captopril then caused a fall in MAP to normal. These data reveal the conversion from a renin-independent to a renindependent kind of hypertension after spironolactone therapy in three patients with primary aldosteronism syndrome. This might be of pathogenetic and therapeutic interest.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemical Engineering & Technology - CET 10 (1987), S. 262-271 
    ISSN: 0930-7516
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Pressure pulsations in hydraulic systems, generated by reciprocating pumps, can cause serious problems with regard to plant safety and reliability. In particular, fatigue problems arise in high-pressure piping systems. The available knowledge is not sufficient for an accurate computation of pressure peaks in the piping of reciprocating pumps. A number of calculation models are available which, however, neglect both fluid compressibility and friction. This contribution presents a calculation method which allows a precise modelling of various pump installations. Comparison of calculated and experimental data shows a good agreement and provides a validation of the computational model.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Schwellende Innendruckbeanspruchungen treten in Behältern, Reaktoren, Rohrleitungen, Armaturen, Pumpen und Verdichtern auf. Bei Apparaten wird die schwellende Beanspruchung oft nur durch die Inbetriebnahme und den Abschaltvorgang verursacht, so daß die Lastspielzahl innerhalb der Lebenszeit des Bauteils klein ist. In diesen Fällen werden die Bauteile nach der Zeitfestigkeit ausgelegt. Bei Pumpen und Verdichtern jedoch ist die Lastspielzahl sehr hoch, so daß, abgesehen von wenigen Ausnahmen, eine Auslegung auf Dauerfestigkeit erforderlich ist. Die Bauteile des Pumpen- und Verdichterbaues, welche im Dauerbetrieb durch schwellenden Innendruck belastet sind, sowie die dafür verwendeten Werkstoffe werden auf den Hochdruckmaschinenbau abgestimmt, weshalb nur verhältnismäßig dickwandige Bauteile behandelt werden. Es werden Versuchsergebnisse mitgeteilt und Hinweise für die Auslegung, die Wahl des Werkstoffes und die Oberflächenbehandlung gegeben.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An einer Kolbenpumpe mit Acrylglas-Zylinder wird das Verhalten der Ventile ohne Kavitation und bei verschiedener Stärke der Dampfblasenbildung beobachtet und anhand von Ventilhub- und Druckabfallkurven diskutiert. Die Ergebnisse werden mit stationären Messungen verglichen. Es zeigt sich, daß bei nichtkavitierendem Pumpenbetrieb der Druckabfall im Saugventil aus den bei stationärer Strömung gemessenen Verlustbeiwerten ζv = f (Re) berechnet werden kann. Abschließend werden die Auswirkungen verschiedener Kavitationszustände auf das Betriebsverhalten der Pumpe beschrieben und Maßnahmen zur Vermeidung schädlicher Kavitation genannt.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 39 (1967), S. 449-457 
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Zur Dosierung gefährlicher, aggressiver und verschleißend wirkender Medien werden immer häufiger stopfbuchslose Dosierpumpen in Faltenbalg- und Membranausführung angewendet. Hierbei haben die Pumpen mit mechanischem Verdrängerantrieb den Vorzug einfacher Bedienung und Wartung, jedoch sind Förderströme, Förderdrücke und Temperaturen begrenzt. Die komplizierteren und teureren Ausführungen mit hydraulischem Verdrängerantrieb gestatten auch höhere Drücke; der Verdränger wird günstiger beansprucht, und das Hubvolumen ist stets genau definiert. Auf Grund von Untersuchungsergebnissen, Auslegungs- und Anwendungserfahrungen werden Anwendungsbereich, Saugvermögen, Strahlenresistenz, Förderverhalten, Dosiergenauigkeit, Lebensdauer und Dichtheit der stopfbuchslosen Dosierpumpen erörtert. Für die Planung dient ein Überblick zur Anwendung stopfbuchsloser Dosierpumpen.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 68 (1996), S. 1462-1466 
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 71 (1999), S. 888-889 
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 69 (1997), S. 1003-1004 
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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