In:
CHIMIA, Swiss Chemical Society, Vol. 57, No. 11 ( 2003-11-01), p. 715-
Abstract:
Novel phenylpyridines were synthesized based on molecular modeling oriented design by superposition of herbicidal phenyl-uracils, -indazoles, and diphenylethers. Their preparation follows Suzuki-type coupling conditions of reactive 2-chloro-pyridines with appropriate 2,5-substituted
4-chloro-phenyl boronic acids. Depending on the nature of substituents in the pyridine, and in particular the phenyl group, a large number of derivatives are readily accessible. Besides open-chain phenylpyridines also anellated compounds, such as pyridine-substituted 2H-1,4-benzothiazin-3(4H)-one or 3,4-dihydro-1H-quinolin-2-one, were prepared. Phenylpyridines act by inhibition of protoporphyrinogen-IX-oxidase. Their synthesis will be described in conjunction with structure–activity relationships. Phenylpyridines are highly active against many important broadleaf and grass weed
species under pre- and – in particular – post-emergent conditions.
Type of Medium:
Online Resource
ISSN:
2673-2424
,
0009-4293
DOI:
10.2533/000942903777678650
Language:
Unknown
Publisher:
Swiss Chemical Society
Publication Date:
2003
detail.hit.zdb_id:
2179192-2
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