In:
Journal of General Virology, Microbiology Society, Vol. 84, No. 3 ( 2003-03-01), p. 603-606
Abstract:
Human immunodeficiency virus type 1 (HIV-1) Tat and human Cyclin T1 form a complex and together recognize the viral TAR RNA element with specificity. Using HIV-1/equine infectious anaemia virus TAR chimeras, we show that in addition to the well-characterized interaction with the bulge, Tat recognizes the distal stem and the loop of TAR. These data support previously proposed, but unproven, molecular models.
Type of Medium:
Online Resource
ISSN:
0022-1317
,
1465-2099
DOI:
10.1099/vir.0.18645-0
Language:
English
Publisher:
Microbiology Society
Publication Date:
2003
detail.hit.zdb_id:
2007065-2
SSG:
12
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