In:
Annals of Neurology, Wiley, Vol. 55, No. 1 ( 2004-01), p. 113-118
Abstract:
Two novel mutations recently have been identified in the DJ‐1 gene that cause a new form of autosomal recessive, early‐onset parkinsonism. Because the pathological role of this protein is unknown, we examined the issue here and report the colocalization of DJ‐1 protein within a subset of pathological tau inclusions in a diverse group of neurodegenerative disorders known as tauopathies. Our study extends the view that different neurodegenerative diseases may have similar pathological mechanisms, and that these processes likely include DJ‐1.
Type of Medium:
Online Resource
ISSN:
0364-5134
,
1531-8249
Language:
English
Publisher:
Wiley
Publication Date:
2004
detail.hit.zdb_id:
2037912-2
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