In:
Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 225, No. 4 ( 2004-08-01), p. 540-544
Abstract:
Objective —To evaluate the effects of hydromorphone, hydromorphone and glycopyrrolate, medetomidine,
and butorphanol premedication on the difficulty and time required to pass an endoscope into the
stomach and duodenum of cats anesthetized with ketamine and isoflurane. Design —Randomized complete block crossover
study. Animals —8 purpose-bred adult female cats. Procedures —Each cat was premedicated and anesthetized
4 times with an interval of at least 7 days between procedures. Cats were premedicated with
hydromorphone, hydromorphone and glycopyrrolate, medetomidine, or butorphanol administered IM. Twenty
minutes after premedication, sedation was assessed by use of a subjective ordinal scale. Cats received ketamine
administered IM, and 10 minutes later a cuffed orotracheal tube was placed and anesthesia maintained
with isoflurane. Cats breathed spontaneously throughout the procedure. When end-tidal isoflurane concentration
was stable at 1.4% for 15 minutes, endoscopy was begun. The times required to pass the endoscope
through the cardiac and pyloric sphincters were recorded, and the difficulty of endoscope passage was scored
by use of a subjective ordinal scale. Results —No significant differences in difficulty or
time required to pass the endoscope through the cardiac and pyloric sphincters were found among premedicant
groups. Premedication with medetomidine resulted in the greatest degree of sedation and
longest time to return to sternal recumbency. Conclusions and Clinical Relevance —Results suggest
that hydromorphone, hydromorphone and glycopyrrolate, medetomidine, and butorphanol at the
doses tested can be used satisfactorily to premedicate cats prior to general anesthesia for gastroduodenoscopy.
( J Am Vet Med Assoc 2004;225:540–544)
Type of Medium:
Online Resource
ISSN:
0003-1488
DOI:
10.2460/javma.2004.225.540
Language:
Unknown
Publisher:
American Veterinary Medical Association (AVMA)
Publication Date:
2004
detail.hit.zdb_id:
2904887-4
SSG:
22
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