In:
FEBS Letters, Wiley, Vol. 472, No. 2-3 ( 2000-04-28), p. 230-234
Abstract:
Two mouse genes, Mit1 / Lb9 and Copg2 , linked to Peg1 / Mest on mouse chromosome 6, were identified to be imprinted maternally and paternally, respectively. Mit1 / Lb9 encoding untranslated transcripts resides within the intron 20 of Copg2 . The gene is maternally imprinted in adult mouse brain, partially imprinted in other tissues. Copg2 consists of 24 exons within the 〉 40 kb genomic region, being expressed ubiquitously in mouse tissues with a partial imprinting pattern in embryos, neonates, and adult brain in contrast to maternally imprinted human COPG2 . In addition, we identified an antisense transcript of Copg2 , Copg2AS , which overlaps 3′‐UTRs of Copg2 and Peg1 / Mest . The Copg2AS transcript is maternally imprinted in embryos, neonates, and adult tissues.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/S0014-5793(00)01461-7
Language:
English
Publisher:
Wiley
Publication Date:
2000
detail.hit.zdb_id:
1460391-3
SSG:
12
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