GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2000-2004  (18)
  • 1980-1984  (31)
  • 1950-1954  (3)
Document type
Language
Years
Year
  • 1
    Keywords: Oxygen--Physiological transport--Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (394 pages)
    Edition: 1st ed.
    ISBN: 9781461502050
    Series Statement: Advances in Experimental Medicine and Biology Series ; v.510
    Language: English
    Note: OXYGEN TRANSPORT TO TISSUE XXIII -- Editor's page -- Copyright -- INTERNATIONAL SOCIETY ON OXYGEN TRANSPORT TO TISSUE 2001 -- SPONSORS -- PREFACE -- CONTENTS -- THE ROLE OF TUMOR OXYGENATION IN VASCULAR AND CLINICAL RESPONSE TO ANGIOGENESIS INHIBITION -- COMPARISON OF FLUCTUATIONS OF OXYGEN TENSION IN FSA, 9L, AND R3230AC TUMORS IN RATS -- EFFECT OF CARBOGEN-BREATHING ON REDOX STATUS OF THE RIF-1 TUMOR -- EVALUATION OF MICROREGIONAL VARIATIONS IN TUMOR HYPOXIA FOLLOWING THE ADMINISTRATION OF ENDOSTATIN -- EFFECT OF HYDRALAZINE ON BLOOD FLOW, OXYGENATION, AND INTERSTITIAL FLUID PRESSURE IN SUBCUTANEOUS TUMORS -- OXYGENATION OF CERVIX CANCERS: IMPACT OF CLINICAL AND PATHOLOGICAL PARAMETERS -- QUANTITATIVE SPATIAL ANALYSIS OF HYPOXIA AND VASCULAR PERFUSION IN TUMOR SECTIONS* -- TUMOR OXYGENATION AND ITS RELEVANCE TO TUMOR PHYSIOLOGY AND TREATMENT -- MECHANISMS UNDERLYING HYPOXIA DEVELOPMENT IN TUMORS -- LACK OF ASSOCIATION BETWEEN TUMOR HYPOXIA, GLUT-1 EXPRESSION AND GLUCOSE UPTAKE IN EXPERIMENTAL SARCOMAS -- THE IMPACT OF TISSUE MICROENVIRONMENT ON TREATMENT SIMULATION -- EVIDENCE FOR AND AGAINST HYPOXIA AS THE PRIMARY CAUSE OF TUMOR AGGRESSIVENESS -- CHARACTERIZATION OF HUMAN Gc PROTEIN-DERIVED MACROPHAGE ACTIVATION FACTOR (GcMAF) AND ITS FUNCTIONAL ROLE IN MACROPHAGE TUMORICIDAL ACTIVITY -- EFFECT OF HEMOGLOBIN SOLUTIONS AS HEMODILUENTS ON CAPILLARY OXYGEN TENSION -- DIFFERENT EFFICACY IN VITRO OF HEMOGLOBIN BASED OXYGEN CARRIERS AND RED CELLS -- A NOVEL BLOOD TRANSFUSANT CANDIDATE: INTACT HUMAN ERYTHROCYTES CONTAINING HEMOGLOBIN EXCLUSIVELY NITROSYLATED IN THE α-SUBUNITS -- THE CONTRIBUTION OF HEMOGLOBIN TO OXYGEN TRANSPORT IN THE MICROCRUSTACEAN DAPHNIA MAGNA -- MODIFICATIONS OF RED BLOOD CELL SHAPE AND GLYCOPROTEINS MEMBRANE CONTENT IN SEPTIC PATIENTS. , FIBER OPTIC IMMUNOSENSORS FOR CARDIOVASCULAR DISEASE DIAGNOSIS: Quantification of Protein C, Factor V Leiden, and cardiac Troponin T in plasma -- SOFT GEL CHROMATOGRAPHY COLUMN ANALYSIS AND DESIGN FOR THE PRODUCTION OF HIGH MOLECULAR WEIGHT BLOOD FACTORS: MODEL MOLECULE PROTEIN C -- DEVELOPMENT OF AN ECONOMIC MINIANTIBODY PRODUCTION PROCESS FOR THE PURIFICATION OF PROTEIN C (ANTI-COAGULANT/ANTI-THROMBOTIC) -- NITRIC OXIDE SYNTHESIS IN BRAIN IS STIMULATED BY OXYGEN -- OXYGEN INDIRECTLY REGULATES NITRIC OXIDE AVAILABILITY -- MODELING THE REGULATION OF OXYGEN CONSUMPTION BY NITRIC OXIDE -- OXYGEN SENSOR DESIGN: ANALYSIS AND CORRECTION OF PROBLEMS ASSOCIATED WITH ZERO CURRENT, STABILITY AND STRUCTURE -- COMPUTER SIMULATION OF OXYGEN MICROELECTRODE MEASUREMENTS IN TISSUES -- PHYSIOLOGICAL OXYGEN MEASUREMENTS USING OXYGEN ELECTRODES -- ACCURACY OF A POLAROGRAPHIC ELECTRODE AT HIGH OXYGEN CONCENTRATIONS -- RECESSED OXYGEN ELECTRODES: GETTING MORE THAN PO2 -- OXYGEN DISTRIBUTIONS IN TISSUE MEASURED BY PHOSPHORESCENCE QUENCHING -- ADAPTING AND VALIDATING A NIRS DEVICE TO MEASURE IN UTERO FETAL SHEEP CEREBRAL OXYGENATION -- DETECTION OF THE FAST NEURONAL SIGNAL ON THE MOTOR CORTEX USING FUNCTIONAL FREQUENCY DOMAIN NEAR INFRARED SPECTROSCOPY -- Probing Rat Brain Oxygenation with Near-Infrared Spectroscopy (NIRS) and Magnetic Resonance Imaging (MRI) -- VARIATION IN BLOOD OXYGENATION AND CEREBRAL pO2 IN A MOUSE MODEL MEASURED BY EPR SPECTROMETRY -- FUNCTIONAL OXYGEN-17 MAGNETIC RESONANCE IMAGING AND LOCALIZED SPECTROSCOPY -- DEVELOPMENT OF A RETRACTOR FOR MONITORING THE OXYGENATION STATE OF BRAIN TISSUE -- MAPPING OF HEMODYNAMICS ON THE HUMAN CALF WITH NEAR INFRARED SPECTROSCOPY AND THE INFLUENCE OF THE ADIPOSE TISSUE THICKNESS -- EPR IMAGING OF VASCULAR CHANGES IN OXYGEN IN RESPONSE TO CARBOGEN BREATHING -- MOLECULAR IMAGING BY PET. , FREQUENCY DOMAIN IMAGING OF OXYGEN TENSION IN THE MOUSE RETINA -- OXYGEN DELIVERY TO THE RETINA AND RELATED VISUAL PATHOLOGY -- ACTIVATION OF THE VISUAL CORTEX IN NEWBORN INFANTS UNDER NATURAL SLEEP USING MULTICHANNEL NEAR-INFRARED SPECTROSCOPY -- EFFECT OF BLOOD FLOW ON PvO2-VO2 RELATION IN CONTRACTING IN SITU SKELETAL MUSCLE -- OXYGEN TRANSPORT AND INTRACELLULAR BIOENERGETICS ON STIMULATED CAT SKELETAL MUSCLE -- MUSCLE OXYGENATION BY NEAR INFRARED SPECTROSCOPY AND LACTATE THRESHOLDS IN ENDURANCE TRAINED AND RECREATIONALLY ACTIVE CYCLISTS -- CARDIAC OUTPUT, OXYGEN CONSUMPTION AND MUSCLE OXYGEN DELIVERY IN SUBMAXIMAL EXERCISE -- NON-INVASIVE PET AND SPECT IMAGING OF TISSUE HYPOXIA USING ISOTOPICALLY LABELED 2-NITROIMIDAZOLES+ -- DIFFUSE OPTICAL MEASUREMENT OF HEMOGLOBIN AND CEREBRAL BLOOD FLOW IN RAT BRAIN DURING HYPERCAPNIA, HYPOXIA AND CARDIAC ARREST -- MULTIORGAN MONITORING OF HEMODYNAMIC AND MITOCHONDRIAL RESPONSES TO ANOXIA AND CARDIAC ARREST IN THE RAT -- IMPORTANCE OF GLOMUS CELL PLASMA MEMBRANE AND MITOCHONDRIAL MEMBRANE POTENTIALS DURING ACUTE HYPOXIA SIGNALING IN THE RAT CAROTID BODY -- ESTIMATION OF HYDROXYL RADICALS BASED ON THE SALICYLATE TRAPPING METHOD IN HIPPOCAMPUS OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS (SHRSP) DURING TRANSIENT ISCHEMIA AND RECIRCULATION -- EFFECT OF HYPOXIA AND ISCHEMIA ON EXPRESSION OF SELECTED GENES IN BRAIN OF NEWBORN PIGLETS -- BRAIN OXYGENATION DURING CARDIOPULMONARY BYPASS AND CIRCULATORY ARREST -- EXPRESSION OF ANGIOPOIETIN-1 AND -2 IN THE RAT BRAIN DURING CHRONIC HYPOXIA AND DE-ADAPTATION -- HYPOXIA-INDUCIBLE FACTOR-1α ACCUMULATION IN THE RAT BRAIN IN RESPONSE TO HYPOXIA AND ISCHEMIA IS ATTENUATED DURING AGING -- LUNG ISCHEMIA: ENDOTHELIAL CELL SIGNALING BY REACTIVE OXYGEN SPECIES -- NEAR INFRARED SPECTROSCOPY (NIRS) MEASUREMENTS DURING GLOBAL CEREBRAL ISCHEMIA IN SHEEP. , SIMULATIONS OF CAPILLARY NETWORK OXYGEN TRANSPORT DURING TRANSIENT ISCHEMIA IN THE PRESENCE AND ABSENCE OF TISSUE MYOGLOBIN -- CEREBRAL OXYGENATION DURING CHRONIC OBSTRUCTIVE PULMONARY DISEASE+ -- PHYSIOLOGY OF FUNCTIONAL ACTIVATION -- NONLINEAR ANALYSIS OF HEART RATE VARIABILITY IN INFANTS WITH APPARENT LIFE-THREATENING EVENTS -- THE EFFECT OF NICOTINAMIDE & -- HYPEROXIC GASES ON BLOOD GLUCOSE -- MEASUREMENT OF TISSUE OXYGENATION INDEX DURING THE FIRST THREE DAYS IN PREMATURE BORN INFANTS -- SIMULTANEOUS MEASUREMENT OF CEREBRAL TISSUE OXYGENATION OVER THE ADULT FRONTAL AND MOTOR CORTEX DURING REST AND FUNCTIONAL ACTIVATION -- DYSFUNCTIONAL MICROVASCULAR CONDUCTED RESPONSE IN IRRADIATED NORMAL TISSUE -- OXYGENATION AND BLOOD CONCENTRATION CHANGES IN HUMAN SUBJECT PREFRONTAL ACTIVATION BY ANAGRAM SOLUTIONS -- QUANTITATION OF THE CONCORDANCE BETWEEN CEREBRAL INTRAVASCULAR OXYGENATION AND MEAN ARTERIAL BLOOD PRESSURE FOR THE DETECTION OF IMPAIRED AUTOREGULATION -- EFFECTS OF FLUID PERCUSSION INJURY ON RAT BRAIN HEMODYNAMICS, IONIC, ELECTRICAL ACTIVITY, AND ENERGY METABOLISM IN VIVO -- AUTHOR INDEX -- SUBJECT INDEX.
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 43 (1984), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The effects of kainic acid were investigated in preparations of rat brain synaptosomes. It was found that kainic acid inhibited competitively the uptake of d-[3H]aspartate, with a Ki of approximately 0.3 mm. Kainic acid also caused release of two excitatory amino acid neurotranstnitters, aspartate and glutamate, in a time- and concentration-dependent manner, but had no effect on the content of γ-aminobutyric acid. Concomitant with the release of aspartate and glutamate, depolarization of the synaptosomal membrane and an increase in intracellular calcium were observed, with no measurable change in the concentration of internal sodium ions. The increase in intrasynaptosomal calcium and decrease in transmem-brane electrical potential were prevented by the addition of glutamate, whereas the kainate-induced release of ra-dioactive aspartate was substantially inhibited by lowering the concentration of calcium in the external medium. It is postulated that kainic acid reacts with a class of glutamate receptors located in a subpopulation of synaptosomes, presumably derived from the glutamatergic and aspartatergic neuronal pathways, which possesses high-affinity uptake system(s) for glutamate and/or aspartate. Activation of these receptors causes opening of calcium channels, influx of calcium into the synaptosomes, and depolarization of the synaptosomal plasma membrane with consequent release of amino acid neurotransmitters.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 37 (1981), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Protein synthesis and axonal transport have been studied in regenerating peripheral nerves. Sciatic nerves of bullfrogs were unilaterally crushed or cut. The animals were killed 1, 2, or 4 weeks later, and 8th and 9th dorsal root ganglia removed together with sciatic nerves and dorsal roots. The ganglia were selectively labeled in vitro with [35S]-methionine. Labeled proteins, in dorsal root ganglia and rapidly transported to ligatures placed on the sciatic nerves and dorsal roots, were analyzed by two-dimensional polyacryl-amide gel electrophoresis. Qualitative analysis of protein patterns revealed no totally new proteins synthesized or rapidly transported in regenerating nerves. However, quantitative comparison of regenerating and contralateral control nerves revealed significant differences in abundance for some of the proteins synthesized in dorsal root ganglia, and for a few of the rapidly transported proteins. Quantitative analysis of rapidly transported proteins in both the peripheral processes (spinal nerves) and central processes (dorsal roots) revealed similar changes despite the fact that the roots were undamaged. The overall lack of drastic changes seen in protein synthesis and transport suggests that the neuron in its program of normal maintenance synthesizes and supplies most of the materials required for axon regrowth.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 19 (1980), S. 4213-4221 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 36 (1981), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Synaptosomes isolated on isosmotic Ficoll density gradients are an effective model for some aspects of neuronal function. They maintain metabolic energy levels ([ATP]/[ADP] [Pi1) and transplasma membrane electrical potentials very similar to those of neurons in the intact brain. The concentration of K+ in the external medium (K+-sensitive electrode), O2 uptake, and cytochrome c reduction (550 nm minus 540 nm) were simultaneously monitored in synaptosomal suspensions. Oxidative metabolism is the primary source of intrasynaptosomal ATP and at pH 7.4 anaerobiosis results in K+ leakage at 4.5 ± 0.8 nmol/min/mg protein with glucose as substrate and 10.7 T 1.9 nmol/min/mg protein with lactate plus pyruvate (10:1) as substrate. Reintroduction of oxygen initiates complete (ouabain-sensitive) reuptake of K. at initial rates of 35.4 ± 3.2 nmol/min/mg protein and 18 ± 1.7 nmol K-/min/mg protein, respectively. The rates of K+ leakage and reuptake fall when the pH is lowered from 7.4 to 6.0 but recover fully if the pH is raised to the original value. The rates of K1 release and uptake decrease when the Na- concentration in the medium is decreased and increase when the Ca2- concentration is decreased. The intrasynaptosomal [K+] under aerobic conditions was 77.3 ± 3 MM and the calculated K+ diffusion potential was -72 mV. Anaerobic incubation of the synaptosomes for up to 20 min and at pH values from 7.4 to 6.0 did not produce irreversible impairment of any of the measured variables. These results suggest that permanent loss of brain function following prolonged hypoxia and ischemia is not due to irreversible damage to the synapses with respect to these parameters but rather to impairment of some other neuronal functions.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 34 (1980), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Synaptosomes have been isolated from the brains of nonanesthetized and nembutal-anesthetized rats subjected to 30 min hypoxia induced by breathing 7% oxygen in nitrogen. The respiratory rate was depressed in synaptosomes from starved hypoxic animals but was not significantly different from the respective control values in preparations from fed hypoxic animals, anesthetized animals, and hypoxic nonanesthetized animals allowed to recover from the hypoxic episode by 60 min of normoxic conditions. Observations are also reported concerning the levels of various metabolites in the synaptosomes isolated from the brains of the same groups of animals. It is suggested that hypoxia results in damage to the synaptosomal and/or mitochondrial membrane, which modifies substrate oxidation in the mitochondria and decreases availability of reducing equivalents for the respiratory chain. Results obtained on afflicted and recovered animals indicate that synaptosomal preparations provide a useful model for the study of hypoxic damage.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 38 (1982), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Synaptosomes isolated from the rat cerebral cortex by means of a discontinuous Ficoll gradient carry out net, sodium-dependent, veratridine-sensitive accumulation of γ-aminobutyric acid (GABA), serotonin, norepinephrine, and dopamine. The intrasynaptosomal contents of the four neurotransmitters are: 30.4 nmol/mg protein, 17.4 pmol/mg protein, 13.5 pmol/mg protein, and 21.2 pmol/mg protein, respectively. Anaerobic preincubation of synaptosomes causes an irreversible decrease in the rates of neurotransmitter accumulation but does not affect the rates of their release. The inhibitory effect of anaerobiosis is enhanced by increased concentration of [H+] (decreased pH) in the medium. The most sensitive is the uptake of dopamine, the least that of serotonin. The rates of neurotransmitter efflux are unaffected by anaerobiosis. Synaptosomes leak catecholamines, GABA, and serotonin into the medium when subjected to anaerobiosis, and reintroduction of oxygen is accompanied by a rapid reaccumulation of all four neurotransmitters. It is concluded that: (1) Responses of synaptosomes to anaerobiosis are remarkably similar to the behavior of intact brain in hypoxia and ischemia. (2) Neurotransmitter uptake systems are more sensitive to short periods of anaerobiosis than are either the energy metabolism or ion transport. (3) Some neurotransmitter uptake systems are more easily damaged by anaerobiosis than others.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 34 (1980), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Cellular energetic parameters including the intramitochondrial and cytosolic [NAD+]/[NADH] ratios, the cellular [ATP]/[ADP][Pi and [creatine phosphate]/[creatine] ratios, the concentration of cytochrome c and its redox state and the respiratory rate were studied in suspensions of rat brain synapto-somes isolated from nembutal-anesthetized and nonanesthetized animals. The ratio of [3-hydroxybutyrate] to [acetoacetate] was 2.0 in synaptosomes isolated from nonanesthetized rats and 5.55 in those from anesthetized animals. The [lactate]/[pyruvate] ratio was 3.8 in the former and 10.9 in the latter preparation. The [ATP]/[ADP][Pi] was 3838 M−1 in the synaptosomes from anesthetized rats and 840 M−1 in those from nonanesthetized animals and the [creatine phosphate]/[creatine] ratios were 0.79 and 0.39, respectively. Cytochrome c was about 15% reduced in both preparations; however, the mitochon-drial cytochrome concentration was almost twofold higher in the synaptosomes from nonanesthetized animals. Calculations of the free energy relationships between the mitochondrial redox reactions and ATP synthesis showed that in synaptosomes isolated from the brains of nembutal-anesthetized rats the first two sites of oxidative phosphorylation were at near-equilibrium, in agreement with observations for intact cells and tissues. The energetic parameters for synaptosomes from anesthetized rats are very similar to the values for intact whole brain, whereas those for synaptosomes from nonanesthetized rats are lower and suggest that nembutal anesthesia protects against some irreversible damage to the synaptosome during isolation. It is concluded that synaptosomes isolated from brains of nembutal-anesthetized rats can be used as a convenient model system for studies of neuronal metabolism.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...