GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Axon-sprouting  (1)
  • Best. von Wasser in Methanol  (1)
  • Brain damage  (1)
  • Springer  (3)
  • Blackwell Publishing Ltd
  • Blackwell Science, Ltd
  • Nature Publishing Group
  • 2000-2004
  • 1985-1989  (2)
  • 1980-1984
  • 1975-1979  (1)
  • 1955-1959
  • 1880-1889
Publikationsart
Schlagwörter
Verlag/Herausgeber
  • Springer  (3)
  • Blackwell Publishing Ltd
  • Blackwell Science, Ltd
  • Nature Publishing Group
Erscheinungszeitraum
  • 2000-2004
  • 1985-1989  (2)
  • 1980-1984
  • 1975-1979  (1)
  • 1955-1959
    • +
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    The principle of “conservation of total axonal arborizations”: massive compensatory sprouting in the hamster subcortical visual system after early tectal lesions (1988)
    Springer
    Experimental brain research 73 (1988), S. 505-518 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Visual system ; Neuroplasticity ; Axon-sprouting ; Pruning
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Unilateral lesions of the right superior colliculus (SC) were made in hamsters on the day after birth. In order to quantify the extent of abnormal innervation by left eye fibers in the diencephalon and midbrain, the left eye was removed on postnatal day 12 or 36, and after an appropriate survival time, the brains were stained for degenerating axons and axon terminals with the Fink-Heimer method. In additional cases, anterograde transport of 3H proline-leucine or horseradish peroxidase was used to assess left eye connectivity. In agreement with previous reports we found abnormal projections in the ventral nucleus of the lateral geniculate body (LGv), in the lateral posterior nucleus (LP) of the thalamus, and in the left SC (the ‘recrossing’ pathway). We also noted areas of abnormally heavy terminal fields arranged in patches in coronal sections in the dorsal nucleus of the lateral geniculate body (LGd). These patches arise from columns of dense innervation that are oriented along a rostral-to-caudal axis. If the right SC lesion was made large enough to diminish the recrossing pathway, retinofugal axons establish a significantly smaller distal terminal field in the left SC. In these cases, a corresponding increase in the size of terminal fields in all major proximal structures (LGd, LGv, LP, DTN) was observed. The sum of abnormal proximal growth (“compensatory sprouting”) was found to truly compensate for the distal loss of terminals. The evaluation of hamsters in which left eye connectivity was assessed at the age of 12 days revealed that lesion-induced patches of abnormal growth have already reached their full size by that time. These findings provide evidence for the ‘pruning -effect’ and demonstrate that retinofugal axons support a fixed number of terminal arborizations (the principle of ‘conservation of total axonal arborizations’).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00406608
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Enhanced sprouting of retinotectal fibers after early superior colliculus lesions in hamsters treated with gangliosides (1988)
    Springer
    Experimental brain research 71 (1988), S. 365-376 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Gangliosides ; Brain damage ; Axonal sprouting ; Secondary degeneration ; Retinotectal system
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of exogenous gangliosides on sprouting of optic tract axons was studied in hamsters which, after a right tectal lesion on the day after birth (P1), had an abnormal retinotectal projection from the left eye to the left superior colliculus (SC). Sprouting of these axons was induced by removing the competing input by right eye removal on postnatal day 9 (P9). Intraperitoneal GM1, given daily and started on P9, significantly stimulated the sprouting response. This was demonstrated by Fink-Heimer silver staining of anterograde axonal degeneration three days after the left eye was removed on P36. Terminal fields in the left SC were, in average, twice as large compared to controls. An estimate of the total number of terminals (silver stained particles) revealed a value of 7.9×106 for GM1 and 3.2×106 for control hamsters, respectively. Diencephalic structures which also receive collateral input from the sprouting optic tract did not show any alterations in the size of the terminal field due to GM1-treatment, suggesting that, in vivo, gangliosides fail to initiate sprouting in areas that have not previously been denervated. Unexpectedly, GM1-treated hamsters also had significantly smaller right SC damage and less left damage near the midline. Subsequent reanalysis of the data based on a lesion-matching procedure indicates that effects on reducing atrophy were independent of the GM1-enhanced sprouting of retinofugal axons. These findings provide the first direct evidence that exogenous GM1 stimulates lesion-induced axon sprouting in the mammalian brain.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00247496
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Bestimmung kleiner Wassergehalte in Methanol mittels Differentialthermoanalyse (DTA) (1977)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 286 (1977), S. 216-218 
    Details
    ISSN: 1618-2650
    Schlagwort(e): Best. von Wasser in Methanol ; Thermoanalyse, Differential ; 0,02–1 Mol-%, Vergleich mit anderen Verfahren
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Eine Methode zur Bestimmung kleiner Wassergehalte in Methanol (0,02–1 Mol-%) mit Differentialthermoanalyse (DTA) wird beschrieben. Die Wirksamkeit verschiedener Trocknungsverfahren wird untersucht. Das Verfahren wird im Vergleich mit anderen Wasserbestimmungsmethoden in organischen Flüssigkeiten diskutiert.
    Notizen: Abstract A method is described in order to determine small water contents in methanol (0.02–1 mol-%) by differential thermal analysis. The efficiency of different drying procedures is studied. The technique is discussed in comparison with other methods of water analysis in organic liquids.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01155590
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...