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  • 2005-2009  (2)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 19 (2005), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective  The aim of the study was to investigate the state of ultraviolet (UV) A dosimetry in photopatch testing centres in Europe.Background  It has been acknowledged that a widespread disparity exists in the way photopatch testing is carried out in different countries throughout Europe. This prompted the formation of a European taskforce that developed a consensus methodology. One issue that was not addressed directly was that of UVA dosimetry, which clearly impacts on the consistency of the clinical results.Study design  Ten UV meters from photopatch test centres throughout Europe were set up at a reproducible position from a photopatch test light source containing UVA fluorescent lamps and the irradiances were noted from each meter. One meter served as a reference meter with calibration carried out in an optical laboratory traceable to the National Physical Laboratory.Results  The mean of all the measurements was 5.74 mW/cm2 with a SD of 0.36 mW/cm2. Expanded uncertainty at 95% confidence level was 12%.Conclusions  It is desirable that meter calibration should have an accuracy of the order of ±10%. The variation in recorded values among the 10 meters investigated was within acceptable limits. The meter must be calibrated using a similar light source to that used in the phototest equipment, in this case a UVA fluorescence lamp.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Dead Sea (DS) salt solution soaks are used in combination with narrowband ultraviolet B (NB-UVB) to treat psoriasis in many centres, particularly in continental Europe. No previously published controlled study has assessed DS salt + NB-UVB balneophototherapy.Objectives  To compare DS salt balneophototherapy with NB-UVB monotherapy for chronic plaque psoriasis.Methods  Sixty patients with chronic plaque psoriasis participated in this paired, controlled study, with pretreatment DS salt soaks randomly allocated to each participant's right or left study limb. Psoriasis severity was assessed with a Scaling, Erythema and Induration score by a blinded observer. Assessments were weekly during the therapy course, and thereafter 8-weekly until relapse or for up to 1 year after clearance.Results  The mean area under the psoriasis severity–time curves during treatment was not detectably lower with DS salt balneophototherapy than with NB-UVB monotherapy (P = 0·099). The psoriasis severity score fell slightly more from beginning to end of courses with DS salt balneophototherapy than with NB-UVB monotherapy (P = 0·019). There was no detectable difference in times to relapse.Conclusions  In this population the addition of pretreatment DS salt soaks to NB-UVB did not result in a clinically important improvement in clearance of psoriasis.
    Type of Medium: Electronic Resource
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