ISSN:
1662-0356
Quelle:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Thema:
Allgemeine Naturwissenschaft
,
Technik allgemein
Notizen:
A highly sensitive method for detecting oligonucleotide targets has been developed usingquantum dot (QD) functionalized nanotubes (NTs) that contain a cascade energy band-gaparchitecture. Their assembly with different types of QDs by the layer-by-layer (LBL) allowed forthe formation of fluorescence resonance energy transfer (FRET) structures in the NTs resulting inan enhanced fluorescence emission from dye labeled oligonucleotide targets captured by probeDNA through hybridization. This approach results in a significant enhancement of detection of dyelabeled oligonucleotide targets. The promising increase in detection sensitivity allows for lowdetection limits by tuning the QD emission, adding other types of QDs, or adjusting the distancebetween all photoactive compounds in the NTs. Hence, the strategy used here to produce newhybrid materials may pave a way for broadening application of NTs in the field of biochemicalmaterials, e.g. sensitive biosensors
Materialart:
Digitale Medien
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/42/transtech_doi~10.4028%252Fwww.scientific.net%252FAST.55.84.pdf
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