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  • 1
    Online Resource
    Online Resource
    National Library of Serbia ; 2005
    In:  Arhiv za onkologiju Vol. 13, No. 1 ( 2005), p. 16-17
    In: Arhiv za onkologiju, National Library of Serbia, Vol. 13, No. 1 ( 2005), p. 16-17
    Abstract: BACKGROUND: Malignant fibrous histiocytoma is most common soft tissue sarcoma occurring in late adult life, most in the extremities and in the retroperitoneum, usually developing in deep fascia or skeletal muscle. Because of the aggressive nature of the tumor early and complete surgical removal is indicated. The overall survival rate of patients with malignant fibrous histiocytoma ranges from 36% to 58% at 5 years. Malignant fibrous histiocytoma in Vojvodina is still rare malignancy either in incidence or in mortality in both sexes. The population of Vojvodina is about 2 100 000. METHODS: We used a descriptive epidemiological method to analyze incidence and mortality from malignant fibrous histiocytoma in Vojvodina. This study is based on the Cancer Registry data for the ten-year period from 1993 to 2002. RESULTS: During the observed period 37 cases of malignant fibrous histiocytoma were reported (19 men and 18 women). The average age of patients was 50 years. The body site distribution differed between sexes and malignant fibrous histiocytoma was more common on the trunk (retroperitoneum) in men and on the lower limbs in women. The average annual incidence rate for the observed period was 1.82 per 1 000 000 for both sexes. The incidence rate changed irregularly over the observed period with the peak of 9 cases (4.55 per 1 000 000) in 2001. The overall linear trends of incidence and of mortality showed a slight increasing tendency in both sexes, but not significantly. Concerning mortality, the similar patterns were noticed. The mortality rate was 0.83 per 1 000 000. CONCLUSION: According to epidemiological data we obtained it can be concluded that Province of Vojvodina is not a region with an important risk for malignant fibrous histiocytoma; however, the increase of incidence appearing in both men and women should be taken into account very seriously in future.
    Type of Medium: Online Resource
    ISSN: 0354-7310 , 1450-9520
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2005
    detail.hit.zdb_id: 2380839-1
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  • 2
    In: Arhiv za onkologiju, National Library of Serbia, Vol. 16, No. 3-4 ( 2008), p. 39-41
    Abstract: Background: A rapid increase in the turnover of malignant cells modulates the enzymes level in circulation and may be a prognostic sign of disease progression. We evaluated the activity of serum lactate dehydrogenase and superoxide dismutase in erythrocytes of breast cancer patients immediately after surgery and before adjuvant therapy. Methods: Fourteen newly operated breast cancer patients were included in the study. Lactate dehydrogenase and superoxide dismutase activity were estimated using standard tests for evaluation of enzyme activity. Results: Activity of lactate dehydrogenase was in normal range in all but one sample obtained from patient at clinical status IIIB. Superoxide dismutase activity was elevated in 11 out of 14 patients, and was 2 to 8 fold higher compare to control values. The highest activity of superoxide dismutase was found in samples of two patients at clinical status I. Conclusion: Determination of lactate dehydrogenase and superoxide dismutase activity might be useful in clinical follow up of breast cancer patients.
    Type of Medium: Online Resource
    ISSN: 0354-7310 , 1450-9520
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2008
    detail.hit.zdb_id: 2380839-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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