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  • SAGE Publications  (2)
  • 2005-2009  (2)
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  • SAGE Publications  (2)
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  • 2005-2009  (2)
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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2005
    In:  Clinical Rehabilitation Vol. 19, No. 8 ( 2005-12), p. 870-877
    In: Clinical Rehabilitation, SAGE Publications, Vol. 19, No. 8 ( 2005-12), p. 870-877
    Abstract: Objective: To investigate the effect of home exercises on the motor performance of patients with Parkinson's disease. Design: A prospective blinded study with allocation of patients into their groups by alternate weeks. Setting: A University Hospital neurology and physiotherapy department. Subjects: Recruited from a movement disorders outpatient clinic of Cerrahpasa School of Medicine diagnosed with Parkinson's disease, classified as Hoehn and Yahr Grades I, II and III. Interventions: Patients who fulfilled the inclusion criteria were recruited to the study. Each patient was evaluated at the end of first and second month after the baseline evaluation. Patients were divided into two groups. Those in the first and third week were put in the exercise group and second and fourth week in the control group. Patients in the exercise group (n=15) were given a schedule of exercises to undertake at home; the others (n=15) did not receive this instruction. Measures: Ten- and 20-m walking test, first pace length, pace number in 10 m, walking around a chair, Nine Hole Peg Board (NHPB) test. Results: Following the home exercise programme, patients in the exercise group showed improvement in walking 10 and 20 m, time elapsed to complete walking around a chair and length of the first pace length, and in the motor performance of both hands (p 〈 0.001). Conclusions: A home-based rehabilitation programme for patients with Parkinson's disease helped to improve motor performance compared to patients who did not take advantage of a regular, professionally designed exercise programme.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2028323-4
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2009
    In:  Cephalalgia Vol. 29, No. 10 ( 2009-10), p. 1059-1068
    In: Cephalalgia, SAGE Publications, Vol. 29, No. 10 ( 2009-10), p. 1059-1068
    Abstract: It has been recently noticed that dust originating from deserts can be transported to other continents by the atmosphere and has an adverse effect on public health, such as increased asthma attacks. Dust originating from the Saharan Desert could initiate a series of reactions upon contact with cloud water and results in the formation of reduced iron (Fe 2+ ), oxalate and various basic amino acids. We aimed to evaluate whether the simulation of Saharan dust-containing atmospheric conditions could trigger the trigeminovascular system. Freely moving rats incubated within simulated atmospheric conditions containing (i) Saharan dust, (ii) Co 60 gamma ray-treated Saharan dust (sterilized) and (iii) dust-free air, were investigated for the presence of c-fos expression in trigeminal nucleus caudalis (TNC) and for NOx (nitrate+nitrite) levels in blood samples. Atmospheric samples were analysed for microorganisms. Saharan dust-containing atmospheric conditions induced c-fos expression in nociceptive neurons within TNC. The number of c-fos+ neurons in superficial lamina of TNC was significantly higher in the Saharan dust group (32.9 ± 5.3, P = 0.0001) compared with dust-free air (11.02 ± 2.7) or Co 60 -treated Saharan dust groups (15.01 ± 2.4). An increase in NOx levels was detected in blood samples of rats exposed to Saharan dust-containing atmosphere. This study has revealed an unknown environmental factor as a possible trigger for headache. It is the first time that transport of Saharan dust with the atmospheric air stream has been documented to be able to trigger the trigeminovascular system in animals. Further studies are needed to explore the mechanisms and molecules that mediate the nociceptive effect and to guide new treatment strategies.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2019999-5
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