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  • SAGE Publications  (32)
  • 2005-2009  (32)
  • 1
    Online Resource
    Online Resource
    Effect of Warm-Supplementing Kidney Yang (WSKY) added to risperidone on quality of life in patients with schizophrenia: a randomized controlled trial
    SAGE Publications ; 2009
    In:  Clinical Rehabilitation Vol. 23, No. 11 ( 2009-11), p. 963-972
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 23, No. 11 ( 2009-11), p. 963-972
    Abstract: Objective: To evaluate the quality of life, efficacy and safety of Warm-Supplementing Kidney Yang (WSKY) added to risperidone in patients with schizophrenia. Design: A randomized controlled trial. Setting: The outpatient and inpatient departments of three hospitals. Subjects: One hundred and twenty patients with clinically diagnosed schizophrenia with predominantly negative symptoms were included in the study. Intervention: All 120 patients were randomly assigned to double-blind treatment with WSKY group (n = 60) or placebo group (n = 60) added to risperidone for eight weeks. Main measure: The efficacy measures included the World Health Organization Quality of Life Scale (WHOQOL-100), the Positive and Negative Syndrome Scale (PANSS), the Social Disability Screening Schedule and the Hamilton Rating Scale for Depression. Safety and tolerability were assessed throughout the trial. Results: The scores of quality of life in the WSKY group showed statistically significant improvement at the end-point of treatment compared with those in the placebo group (WSKY, increasing 40.5 (29.4); placebo, increasing 14.4 (27.1); F =24.900, P 〈 0.001), while the scores of social function and depression symptoms also showed statistically significant improvement. The response rates for the WHOQOL-100 total scores were 50.0% for the WSKY group versus 31.7% for placebo group (χ 2 = 4.172, P=0.041). There were no significant differences in the safety/tolerability measures between the WSKY group and the placebo group during treatment. Conclusions: The results suggest that WSKY added to risperidone significantly improved the quality of life, social function, depression symptom compared with placebo added to risperidone.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215508101743
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2028323-4
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  • 2
    Online Resource
    Online Resource
    Reduction cleavage of S–S bond by Zn/Cp 2 TiCl 2 : Application for the synthesis of β-arylthiocarbonyl compounds
    SAGE Publications ; 2009
    In:  Journal of Chemical Research Vol. 2009, No. 12 ( 2009-12), p. 750-752
    Details
    In: Journal of Chemical Research, SAGE Publications, Vol. 2009, No. 12 ( 2009-12), p. 750-752
    Abstract: Diaryl disulfides were reduced efficiently by a Zn/Cp 2 TiCl 2 system at room temperature in dry THF to give the corresponding nucleophilic sulfur anion–titanocene complex, followed by reaction with α, β-unsaturated esters (ketones or nitriles) to afford the corresponding β-arylthioesters(ketone or nitrile) in good yields.
    Type of Medium: Online Resource
    ISSN: 1747-5198 , 2047-6507
    URL: Article
    DOI: 10.3184/030823409X12592534682310
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 3010810-X
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  • 3
    Online Resource
    Online Resource
    Cutoff value of carcinoembryonic antigen and carbohydrate antigen 19-9 elevation levels for monitoring recurrence in patients with resectable gastric adenocarcinoma
    SAGE Publications ; 2009
    In:  The International Journal of Biological Markers Vol. 24, No. 4 ( 2009-10), p. 258-264
    Details
    In: The International Journal of Biological Markers, SAGE Publications, Vol. 24, No. 4 ( 2009-10), p. 258-264
    Abstract: The aim of this longitudinal study was to try and improve the specificity of carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 in monitoring tumor recurrence in patients with resectable gastric adenocarcinoma by setting suitable elevation levels. Methods One hundred eighty-one patients with resectable gastric adenocarcinoma were considered. Serum samples were obtained preoperatively and every 3 months postoperatively. Results Preoperative CEA and CA19-9 positivity rates were 19.9% and 18.2%. The specificity and sensitivity of CEA elevation to monitor recurrence were 92.9% and 23.4% versus 76.5% and 78.9% in CEA-negative versus CEA-positive patients, respectively. For CA19-9 the specificity and sensitivity were 95.0% and 18.8% versus 60.0% and 83.3% in CA19-9-negative versus CA19-9-positive patients, respectively. When we set the elevation level of CEA at 5 ng/mL, the specificity of CEA elevation to monitor recurrence increased to 94.1% for CEA-positive patients. The specificity increased to 93.3% for CA19-9-positive patients when the CA19-9 elevation level was set at 100 U/mL. Conclusions For CEA- or CA19-9-positive patients with resectable gastric adenocarcinoma we can increase the specificity of CEA and CA19-9 by setting the elevation level of CEA at 5 ng/mL and CA19-9 at 100 U/mL.
    Type of Medium: Online Resource
    ISSN: 1724-6008 , 1724-6008
    URL: Article
    DOI: 10.1177/172460080902400407
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 1475778-3
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  • 4
    Online Resource
    Online Resource
    Cutoff value of carcinoembryonic antigen and carbohydrate antigen 19-9 elevation levels for monitoring recurrence in patients with resectable gastric adenocarcinoma
    SAGE Publications ; 2009
    In:  The International Journal of Biological Markers Vol. 24, No. 4 ( 2009), p. 258-264
    Details
    In: The International Journal of Biological Markers, SAGE Publications, Vol. 24, No. 4 ( 2009), p. 258-264
    Type of Medium: Online Resource
    ISSN: 0393-6155
    URL: Article
    DOI: 10.5301/JBM.2009.2905
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 1475778-3
    SSG: 12
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  • 5
    Online Resource
    Online Resource
    Viscoelastic Behavior Analysis and Application of the Fractional Derivative Maxwell Model
    SAGE Publications ; 2007
    In:  Journal of Vibration and Control Vol. 13, No. 4 ( 2007-04), p. 385-401
    Details
    In: Journal of Vibration and Control, SAGE Publications, Vol. 13, No. 4 ( 2007-04), p. 385-401
    Abstract: A mathematical model of the viscoelastic phenomenon, employing the fractional derivative Maxwell Model (FDMM) is analyzed in order to determine its consistency with thermodynamic principles. In particular, the development of constraints on the parameters of the model guarantees that the FDMM will predict a nonnegative rate of energy dissipation and a nonnegative internal work. The creep compliance and relaxation modulus of the FDMM are obtained in an easier way. It is found that the monotonic non-decreasing creep compliance and monotonic non-increasing relaxation moduli prove a well-behaved viscoelastic phenomenon of the FDMM. The analysis of relaxation modulus indicates that the FDMM represents viscoelastic fluid behavior, with arbitrary fractional derivatives of stress and strain, only if the thermodynamic constraints are satisfied. The steady state sinusoidal response expressions derived in this article are verified using comparisons with experimental force-displacement loops.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    URL: Article
    DOI: 10.1177/1077546307076284
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2070247-4
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  • 6
    Online Resource
    Online Resource
    The Square Flap Method for Cleft Palate Repair
    SAGE Publications ; 2007
    In:  The Cleft Palate-Craniofacial Journal Vol. 44, No. 6 ( 2007-11), p. 579-584
    Details
    In: The Cleft Palate-Craniofacial Journal, SAGE Publications, Vol. 44, No. 6 ( 2007-11), p. 579-584
    Abstract: To introduce a new surgical technique for repair of cleft palate using the square flap method. Design and Setting: A retrospective analysis of prospectively collected data. Patients and Methods: The procedure was performed from 1995 to 2004 in 21 males and 16 females with cleft palates of different types; the patients had a median age of 6.0 years and an average age of 9.4 years (range from 22 months to 23 years). In these patients, the square flap method, consisting of one rhombic flap and four triangular flaps, designed on the soft palate across the defect, was applied to the von Langenbeck procedure. After incisions, the flaps were rotated and advanced, and each flap was inserted into the opposite side and then sutured. The patients were followed from 6 months to 2 years, the velopharyngeal closure was examined by nasopharyngeal fiberscope and/ or x-ray radiography, and a clinical speech evaluation was performed. Results: In all cases, no problem of flap viability was encountered and all healed well. The postoperative results were satisfactory without any complications such as dehiscence, perforation, palatal fistula, or functional disturbance. The velopharyngeal closure and clinical speech evaluation were satisfactory, and the effects of the operation were stable. Conclusions: The technique presented has been effective, with the advantages of palatal closure without tension, good muscular reconstruction, and sufficient lengthening of the soft palate.
    Type of Medium: Online Resource
    ISSN: 1055-6656 , 1545-1569
    URL: Article
    DOI: 10.1597/06-159.1
    RVK:
    XA 36625
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2030056-6
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  • 7
    Online Resource
    Online Resource
    Safety and Immunogenicity from a Phase I Trial of Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine
    SAGE Publications ; 2007
    In:  Antiviral Therapy Vol. 12, No. 7 ( 2007-10), p. 1107-1114
    Details
    In: Antiviral Therapy, SAGE Publications, Vol. 12, No. 7 ( 2007-10), p. 1107-1114
    Abstract: Emergence of severe acute respiratory syndrome (SARS) from the winter of 2002 to the spring of 2003 has caused a serious threat to public health. Methods To evaluate the safety and immunogenicity of the inactivated SARS coronavirus (SARS-CoV) vaccine, 36 subjects received two doses of 16 SARS-CoV units (SU) or 32 SU inactivated SARS-CoV vaccine, or placebo control. Results On day 42, the seroconversion reached 100% for both vaccine groups. On day 56, 100% of participants in the group receiving 16 SU and 91.1% in the group receiving 32 SU had seroconverted. The geometric mean titre of neutralizing antibody peaked 2 weeks after the second vaccination, but decreased 4 weeks later. Conclusion The inactivated vaccine was safe and well tolerated and can elicit SARS-CoV-specific neutralizing antibodies.
    Type of Medium: Online Resource
    ISSN: 1359-6535 , 2040-2058
    URL: Article
    DOI: 10.1177/135965350701200702
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2118396-X
    SSG: 15,3
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  • 8
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    Online Resource
    Synthesis and Crystal Structure of a New Binuclear Iron Carbonyl Cluster Containing the Triphos and μ ,η 2 -OCC 6 H 5 Ligands
    SAGE Publications ; 2006
    In:  Journal of Chemical Research Vol. 2006, No. 1 ( 2006-01), p. 43-44
    Details
    In: Journal of Chemical Research, SAGE Publications, Vol. 2006, No. 1 ( 2006-01), p. 43-44
    Abstract: The new bimetallic cluster [Fe 2 (CO) 4 ( μ,η 2 -OCC 6 H 5 )( μ 4 ,η 3 -CH 3 C(CH 2 PPh 2 ) 2 CH 2 PPh)] 3 has been synthesised from reaction between Fe 3 (CO) 12 1 and the tripodal polyphosphine compound CH 3 C(CH 2 PPh 2 ) 3 (1,1,1-tris(diphenyl-phosphinomethyl)ethane: triphos) 2. The structure of cluster 3 has been established by single-crystal X-ray diffraction method.
    Type of Medium: Online Resource
    ISSN: 1747-5198 , 2047-6507
    URL: Article
    DOI: 10.3184/030823406776331188
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 3010810-X
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  • 9
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    Online Resource
    Immunohistochemical Distribution of NGF, BDNF, NT-3, and NT-4 in Adult Rhesus Monkey Brains
    SAGE Publications ; 2007
    In:  Journal of Histochemistry & Cytochemistry Vol. 55, No. 1 ( 2007-01), p. 1-19
    Details
    In: Journal of Histochemistry & Cytochemistry, SAGE Publications, Vol. 55, No. 1 ( 2007-01), p. 1-19
    Abstract: Immunohistochemical distribution and cellular localization of neurotrophins was investigated in adult monkey brains using antisera against nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). Western blot analysis showed that each antibody specifically recognized appropriate bands of ∼14.7 kDa, 14.2 kDa, 13.6 kDa, and 14.5 kDa, for NGF, BDNF, NT-3, and NT-4, respectively. These positions coincided with the molecular masses of the neurotrophins studied. Furthermore, sections exposed to primary antiserum preadsorbed with full-length NGF, BDNF, NT-3, and NT-4 exhibited no detectable immunoreactivity, demonstrating specificities of the antibodies against the tissues prepared from rhesus monkeys. The study provided a systematic report on the distribution of NGF, BDNF, NT-3, and NT-4 in the monkey brain. Varying intensity of immunostaining was observed in the somata and processes of a wide variety of neurons and glial cells in the cerebrum, cerebellum, hippocampus, and other regions of the brain. Neurons in some regions such as the cerebral cortex and the hippocampus, which stained for neurotrophins, also expressed neurotrophic factor mRNA. In some other brain regions, there was discrepancy of protein distribution and mRNA expression reported previously, indicating a retrograde or anterograde action mode of neurotrophins. Results of this study provide a morphological basis for the elucidation of the roles of NGF, BDNF, NT-3, and NT-4 in adult primate brains.
    Type of Medium: Online Resource
    ISSN: 0022-1554 , 1551-5044
    URL: Article
    DOI: 10.1369/jhc.6A6952.2006
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 1421306-0
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    Association of ACE I/D Gene Polymorphism With Vascular Dementia: A Meta-Analysis
    SAGE Publications ; 2009
    In:  Journal of Geriatric Psychiatry and Neurology Vol. 22, No. 1 ( 2009-03), p. 10-22
    Details
    In: Journal of Geriatric Psychiatry and Neurology, SAGE Publications, Vol. 22, No. 1 ( 2009-03), p. 10-22
    Abstract: Background: Vascular dementia is the second common cause of dementia, only second to Alzheimer's disease in later life, and has a greater mortality risk than Alzheimer's disease among the elderly population group. The angiotensin-converting enzyme insertion/deletion polymorphism as a risk factor in vascular dementia has been suggested, but direct evidence from genetic association studies remain inconclusive. We performed a meta-analysis pooling data from all relevant studies in order to determine the effect of the insertion/deletion polymorphism on the vascular dementia. Methods: We applied a random-effects model or fixed-effects model to combine odds ratio and 95% confidence intervals. Q statistic was used to evaluate the homogeneity, and Egger's test and Funnel plot were used to assess publication bias. Results: A total of 10 studies were included worldwide. Publication bias was not observed. There was no evidence of the association of angiotensin-converting enzyme insertion/deletion polymorphism with the vascular dementia in general or in the Asian populations or in the Caucasian populations. Conclusions: The angiotensin-converting enzyme insertion/deletion polymorphism might be neutral to vascular dementia.
    Type of Medium: Online Resource
    ISSN: 0891-9887 , 1552-5708
    URL: Article
    DOI: 10.1177/0891988708328221
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2094096-8
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