In:
Microbial Physiology, S. Karger AG, Vol. 16, No. 1-2 ( 2009), p. 6-13
Abstract:
〈 i 〉 Gluconobacter oxydans 〈 /i 〉 is famous for its rapid and incomplete oxidation of a wide range of sugars and sugar alcohols. The organism is known for its efficient oxidation of 〈 i 〉 D 〈 /i 〉 -glucose to 〈 i 〉 D 〈 /i 〉 -gluconate, which can be further oxidized to two different keto- 〈 i 〉 D 〈 /i 〉 -gluconates, 2-keto- 〈 i 〉 D 〈 /i 〉 -gluconate and 5-keto- 〈 i 〉 D 〈 /i 〉 -gluconate, as well as 2,5-di-keto- 〈 i 〉 D 〈 /i 〉 -gluconate. For this oxidation chain and for further oxidation reactions, 〈 i 〉 G. oxydans 〈 /i 〉 possesses a high number of membrane-bound dehydrogenases. In this review, we focus on the dehydrogenases involved in 〈 i 〉 D 〈 /i 〉 -glucose oxidation and the products formed during this process. As some of the involved dehydrogenases contain pyrroloquinoline quinone (PQQ) as a cofactor, also PQQ synthesis is reviewed. Finally, we will give an overview of further PQQ-dependent dehydrogenases and discuss their functions in 〈 i 〉 G. oxydans 〈 /i 〉 ATCC 621H (DSM 2343).
Type of Medium:
Online Resource
ISSN:
2673-1665
,
2673-1673
Language:
English
Publisher:
S. Karger AG
Publication Date:
2009
detail.hit.zdb_id:
3042601-7
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