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  • S. Karger AG  (2)
  • 2005-2009  (2)
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  • S. Karger AG  (2)
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  • 2005-2009  (2)
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  • 1
    Online Resource
    Online Resource
    Does a Carbon Ion-Implanted Surface Reduce the Restenosis Rate of Coronary Stents?
    S. Karger AG ; 2005
    In:  Cardiology Vol. 104, No. 2 ( 2005), p. 72-75
    Details
    In: Cardiology, S. Karger AG, Vol. 104, No. 2 ( 2005), p. 72-75
    Abstract: 〈 i 〉 Background: 〈 /i 〉 Neointimal hyperplasia and resulting restenosis limit the long-term success of coronary stenting. Heavy metal ions induce an inflammatory and allergic reaction, and result in in-stent restenosis. However, a carbon ion-implanted surface might prevent heavy metal ions from diffusing into surrounding tissue. 〈 i 〉 Methods: 〈 /i 〉 140 lesions in 140 patients with coronary lesions underwent implantation of carbon-implanted surface stents (Arthos 〈 sup 〉 inert 〈 /sup 〉 stent group, n = 70) or control stents (Arthos stent group, n = 70). The primary end point was the in-stent restenosis and the secondary end point was the value of hs-CRP at 48 h and 6 months after coronary stenting. Clinical and angiographic follow-ups were performed at 6 months. 〈 i 〉 Results: 〈 /i 〉 The rate of in-stent restenosis was lower in the Arthos 〈 sup 〉 inert 〈 /sup 〉 stent group (15.9%, 10/63) than in the Arthos stent group (20.9%, 13/62), but there were no significant differences between both groups (p = 0.56). The value of hs-CRP at 48 h was lower in the Arthos 〈 sup 〉 inert 〈 /sup 〉 stent group (13.9 ± 13.4 mg/dl) than in the Arthos stent group (24.5 ± 26.0 mg/dl) with significant differences (p = 0.04). However, the differences between two groups were not statistically significant at 6 months (p = 0.76). 〈 i 〉 Conclusions: 〈 /i 〉 As compared with a standard coronary stent, a carbon ion-implanted stent shows no considerable benefit for the prevention of in-stent restenosis within the range of this study. Despite all the limitations of this study, a positive effect of a carbon ion-implanted stent in reducing inflammatory reaction after coronary revascularization seems likely.
    Type of Medium: Online Resource
    ISSN: 0008-6312 , 1421-9751
    URL: Article
    DOI: 10.1159/000086688
    RVK:
    XA 36200
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2005
    detail.hit.zdb_id: 1482041-9
    Location Call Number Limitation Availability
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Phenotypic Spectrum and Clinical Characteristics of Apical Hypertrophic Cardiomyopathy: Multicenter Echo-Doppler Study
    S. Karger AG ; 2008
    In:  Cardiology Vol. 110, No. 1 ( 2008), p. 53-61
    Details
    In: Cardiology, S. Karger AG, Vol. 110, No. 1 ( 2008), p. 53-61
    Abstract: 〈 i 〉 Objectives: 〈 /i 〉 The aim of this study was to define the phenotypic spectrum of apical hypertrophic cardiomyopathy (ApHCM) and clinical characteristics pertaining to identified subtypes. 〈 i 〉 Methods: 〈 /i 〉 In 182 consecutive ApHCM patients (58.9 ± 11.2 years; 142 men) with left ventricular ejection fraction ≧50%, we measured end-diastolic wall thickness of all 16 left ventricular segments to determine patterns of hypertrophy. Echo-Doppler parameters, electrocardiography patterns, and clinical findings were analyzed. 〈 i 〉 Results: 〈 /i 〉 ApHCM was classified into three types as pure focal (n = 81), pure diffuse (n = 70) and mixed type (n = 31) according to patterns of hypertrophy. Incidence of atrial fibrillation (5% for pure focal vs. 11% for pure diffuse vs. 23% for mixed type, p 〈 0.05) and left atrial volume index (30.9 ± 11.8, 35.7 ± 14.8, and 41.3 ± 15.9 ml/m 〈 sup 〉 2 〈 /sup 〉 , respectively, p 〈 0.001) were significantly different among subtypes. Peak systolic (6.6 ± 1.0 vs. 6.3 ± 1.2 vs. 5.9 ± 1.1 cm/s, respectively, p 〈 0.05), diastolic (5.1 ± 1.8 vs. 5.0 ± 1.2 vs. 4.1 ± 1.3 cm/s, respectively, p 〈 0.05) mitral annular velocity, E/E′ (13.3 ± 4.2 vs. 13.7 ± 5.4 vs. 16.1 ± 6.1, respectively, p 〈 0.05) were also significantly different. 〈 i 〉 Conclusions: 〈 /i 〉 ApHCM contains three morphologically distinct phenotypes and detailed subtyping is important in the prediction of development of atrial fibrillation, left atrial volume index and left ventricular longitudinal function.
    Type of Medium: Online Resource
    ISSN: 0008-6312 , 1421-9751
    URL: Article
    DOI: 10.1159/000109407
    RVK:
    XA 36200
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2008
    detail.hit.zdb_id: 1482041-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
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