In:
Spectroscopy, Hindawi Limited, Vol. 23, No. 5-6 ( 2009), p. 257-263
Abstract:
The interaction between bovine serum albumin (BSA) and prulifloxacin was investigated by ultraviolet spectrophotometer (UV) and fluorescence spectroscopy in this paper. Two-dimensional (2D) correlation spectroscopy was applied to the analysis of fluorescence spectra. The results of spectroscopic measurements suggested that prulifloxacin (PL) have a strong ability to quench the intrinsic fluorescence of bovine serum albumin through static quenching procedure. Thermodynamic parameter enthalpy changes (Δ H ) and entropy changes (Δ S ) were calculated. Owing to the spectral resolution enhancement in 2D correlation spectroscopy, the structure change of prulifloxacin can be observed.
Type of Medium:
Online Resource
ISSN:
0712-4813
,
1875-922X
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2009
detail.hit.zdb_id:
2068433-2
SSG:
11
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