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  • 2010-2014  (41)
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  • 1
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    Hindcast of oil-spill pollution during the Lebanon crisis in the Eastern Mediterranean, July–August 2006 (2012)
    Elsevier Science Limited
    Details
    Publication Date: 2021-06-25
    Description: MOON (Mediterranean Operational Oceanography Network http://www.moon-oceanforecasting.eu) provides near-real-time information on oil-spill detection (ocean color and SAR) and predictions [ocean forecasts (MFS and CYCOFOS) and oil-spill predictions (MEDSLIK)]. We employ this system to study the Lebanese oil-pollution crisis in summer 2006 and thus to assist regional and local decision makers in Europe, regionally and locally. The MEDSLIK oil-spill predictions obtained using CYCOFOS high-resolution ocean fields are compared with those obtained using lower-resolution MFS hydrodynamics, and both are validated against satellite observations. The predicted beached oil distributions along the Lebanese and Syrian coasts are compared with in situ observations. The oil-spill predictions are able to simulate the northward movement of the oil spill, with the CYCOFOS predictions being in better agreement with satellite observations. Among the free MEDSLIK parameters tested in the sensitivity experiments, the drift factor appears to be the most relevant to improve the quality of the results.
    Description: Published
    Description: 140–153
    Description: JCR Journal
    Description: restricted
    Keywords: Lebanese oil-pollution event; Oil-spill modeling; Operational oceanography; Remote sensing; Levantine Basin ; 03. Hydrosphere::03.02. Hydrology::03.02.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 2
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    Hindcast of Oil Spill Pollution during the Lebanon Crisis, July-August 2006 (2010)
    Details
    Publication Date: 2020-10-15
    Description: The Mediterranean Operational Oceanography Network (MOON ) provides near-real-time information on oil spill detection and predictions that have been used during the Lebanese oil pollution crisis in summer 2006. A MOON decision support system for oil spill monitoring and prediction comprising ocean colour satellite and SAR images, ocean current forecast (MFS-Mediterranean Forecasting System and CYCOFOS-CYprus Coastal Ocean Forecasting & Observing System) and the MEDSLIK oil spill model has been developed. The oil spill predictions obtained with MEDSLIK coupled to the CYCOFOS high-resolution ocean fields are compared with the oil spill predictions obtained using the lower resolution MFS hydrodynamics and both are validated against satellite observations. The predicted beached oil quatity along the Lebanese and Syrian coasts are compared with the in-situ observations. It is found that predictions with both CYCOFOS and MFS ar capable to simulate the northward movement of the oil, with the higher resolution CYCOFOS predictions in better agreement with satellite observations. Among the free MEDSLIK oil spill parameters tested in the sensitivity experiments there are the wind corrections (wind factor and angle) and the depth of coupling between eulerian fields and wind correction. Among them the drift factor appeared the most relevant in order to improve the quality of results suggesting that operational models such as MFS and CYCOFOS still lack of enought resolution and physical process at the air-sea interface. The oil moved from Lat 33°40'N Lon 35°24.75'E northward toward Syria, which was reached in 10 days at Lat 34° 38.451'N Lon 35° 58.377'E; the oil movement is followed up to August 6 when the oil reached 35.5°N.
    Description: Not submitted
    Description: 4.6. Oceanografia operativa per la valutazione dei rischi in aree marine
    Description: JCR Journal
    Description: open
    Keywords: Lebanese oil pollution event ; oil spill modelling ; operational oceanography ; remote sensing ; Levantine Basin ; 03. Hydrosphere::03.01. General::03.01.05. Operational oceanography
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: manuscript
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  • 3
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    Expert assessment of vulnerability of permafrost carbon to climate change (2013)
    In:  EPIC3Climatic Change, 119(2), pp. 359-374, ISSN: 0165-0009
    Details
    Publication Date: 2016-12-13
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 4
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    Hindcast of oil-spill pollution during the Lebanon crisis in the Eastern Mediterranean, July–August 2006 (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: MOON (Mediterranean Operational Oceanography Network http://www.moon-oceanforecasting.eu) pro- vides near-real-time information on oil-spill detection (ocean color and SAR) and predictions [ocean fore- casts (MFS and CYCOFOS) and oil-spill predictions (MEDSLIK)]. We employ this system to study the Lebanese oil-pollution crisis in summer 2006 and thus to assist regional and local decision makers in Europe, regionally and locally. The MEDSLIK oil-spill predictions obtained using CYCOFOS high-resolution ocean fields are compared with those obtained using lower-resolution MFS hydrodynamics, and both are validated against satellite observations. The predicted beached oil distributions along the Lebanese and Syrian coasts are compared with in situ observations. The oil-spill predictions are able to simulate the northward movement of the oil spill, with the CYCO- FOS predictions being in better agreement with satellite observations. Among the free MEDSLIK param- eters tested in the sensitivity experiments, the drift factor appears to be the most relevant to improve the quality of the results.
    Description: The paper was produced using the INGV MFS forecasting-sys- tem product and the OC-UCY CYCOFOS forecasting-system prod- ucts. The MODIS satellite data products were processed at the GOS-CNR-ISAC Rome laboratory using the SeaDAS software devel- oped by NASA GSFC, Greenbelt, Maryland, the HDFLook software developed by The Laboratoire d’Optique Atmosphérique, Univer- sity of Lille, France, and the MS2GT tool box developed by the Uni- versity of Colorado. Procedures for oil-spill detection were developed in the ENVI environment. Processed ENVISAT-ASAR data were made available by Telespazio and JRC. Part of this work was carried out with the support of the PRIMI project (ASI Contract No. I/094/06/0) financed by the Italian Space Agency (ASI).
    Description: In press
    Description: 4.6. Oceanografia operativa per la valutazione dei rischi in aree marine
    Description: JCR Journal
    Description: reserved
    Keywords: Lebanese oil-pollution event ; Oil-spill modeling ; Operational oceanography ; Remote sensing ; Levantine Basin ; 03. Hydrosphere::03.01. General::03.01.05. Operational oceanography
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
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    Expert assessment of vulnerability of permafrost carbon to climate change (2013)
    Springer
    In:  EPIC3Climatic Change, Springer, 119(2), pp. 359-374, ISSN: 0165-0009
    Details
    Publication Date: 2020-02-10
    Description: Approximately 1700 Pg of soil carbon (C) are stored in the northern circumpolar permafrost zone, more than twice as much C than in the atmosphere. The overall amount, rate, and form of C released to the atmosphere in a warmer world will influence the strength of the permafrost C feedback to climate change. We used a survey to quantify variability in the perception of the vulnerability of permafrost C to climate change. Experts were asked to provide quantitative estimates of permafrost change in response to four scenarios of warming. For the highest warming scenario (RCP 8.5), experts hypothesized that C release from permafrost zone soils could be 19–45 Pg C by 2040, 162–288 Pg C by 2100, and 381–616 Pg C by 2300 in CO2 equivalent using 100-year CH4 global warming potential (GWP). These values become 50 % larger using 20-year CH4 GWP, with a third to a half of expected climate forcing coming from CH4 even though CH4 was only 2.3 % of the expected C release. Experts projected that two-thirds of this release could be avoided under the lowest warming scenario (RCP 2.6). These results highlight the potential risk from permafrost thaw and serve to frame a hypothesis about the magnitude of this feedback to climate change. However, the level of emissions proposed here are unlikely to overshadow the impact of fossil fuel burning, which will continue to be the main source of C emissions and climate forcing.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 6
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    Gliders for Research, Ocean Observation and Management - GROOM (2012)
    In:  [Poster] In: Ocean Sciences Meeting 2012, 20.-24.02.2012, Salt Lake City, USA .
    Details
    Publication Date: 2012-11-29
    Type: Conference or Workshop Item , NonPeerReviewed , info:eu-repo/semantics/conferenceObject
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    OceanRep: Poster
  • 7
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    Gliders for Research, Ocean Observation and Management - GROOM (2013)
    In:  [Poster] In: Baltic Sea Science Congress 2013, 26.-30-08.2013, Klaipeda, Lithuania .
    Details
    Publication Date: 2014-01-09
    Type: Conference or Workshop Item , NonPeerReviewed , info:eu-repo/semantics/conferenceObject
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    OceanRep: Poster
  • 8
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    Gliders as a Component of Future Observing Systems (2010)
    OceanObs'09
    In:  In: Proceedings of the "OceanObs'09: Sustained Ocean Observations and Information for Society". , ed. by Hall, J., Harrison, D. E. and Stammer, D. ESA Publication, WPP-306 . OceanObs'09, Venice, Italy.
    Details
    Publication Date: 2012-07-06
    Type: Book chapter , NonPeerReviewed
    Format: text
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    OceanRep: Book chapter
  • 9
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    Gliders for Research, Ocean Observation and Management - GROOM (2012)
    In:  [Poster] In: EGU General Assembly 2012, 22.-27.04.2012, Vienna, Austria .
    Details
    Publication Date: 2012-11-29
    Type: Conference or Workshop Item , NonPeerReviewed , info:eu-repo/semantics/conferenceObject
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    OceanRep: Poster
  • 10
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    Hedgehog Signaling in Squamous Cell Lung Cancer (2014)
    The American Association for Cancer Research (AACR)
    Details
    Publication Date: 2014-03-15
    Description: Purpose: Lung squamous cell carcinoma (LSCC) currently lacks effective targeted therapies. Previous studies reported overexpression of Hedgehog (HH)–GLI signaling components in LSCC. However, they addressed neither the tumor heterogeneity nor the requirement for HH–GLI signaling. Here, we investigated the role of HH–GLI signaling in LSCC, and studied the therapeutic potential of HH–GLI suppression. Experimental Design: Gene expression datasets of two independent LSCC patient cohorts were analyzed to study the activation of HH–GLI signaling. Four human LSCC cell lines were examined for HH–GLI signaling components. Cell proliferation and apoptosis were assayed in these cells after blocking the HH–GLI pathway by lentiviral-shRNA knockdown or small-molecule inhibitors. Xenografts in immunodeficient mice were used to determine the in vivo efficacy of GLI inhibitor GANT61. Results: In both cohorts, activation of HH–GLI signaling was significantly associated with the classical subtype of LSCC. In cell lines, genetic knockdown of Smoothened (SMO) produced minor effects on cell survival, whereas GLI2 knockdown significantly reduced proliferation and induced extensive apoptosis. Consistently, the SMO inhibitor GDC-0449 resulted in limited cytotoxicity in LSCC cells, whereas the GLI inhibitor GANT61 was very effective. Importantly, GANT61 demonstrated specific in vivo antitumor activity in xenograft models of GLI + cell lines. Conclusion: Our studies demonstrate an important role for GLI2 in LSCC, and suggest GLI inhibition as a novel and potent strategy to treat a subset of patients with LSCC. Clin Cancer Res; 20(6); 1566–75. ©2014 AACR .
    Print ISSN: 1078-0432
    Electronic ISSN: 1557-3265
    Topics: Medicine
    Published by The American Association for Cancer Research (AACR)
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