In:
Problems of Endocrinology, Endocrinology Research Centre, Vol. 60, No. 6 ( 2014-12-15), p. 38-44
Abstract:
Modern diagnostics of hypogonadism is based on the results of X-ray and laboratory (biochemical) investigations that reveal the idiopathic form of the disease in the majority of the patients. However, the recent studies have demonstrated a number of genes, whose disturbed function may be responsible for the development of hypogonadism. This creates the prerequisites for the extension of diagnostics of hypogonadism by means of genotyping of the various forms of the pathology in question and thereby may facilitate the choice of the relevant treatment strategy. The present review is focused on the elucidation of the pathogenetic role of candidate genes involved in the development of isolated hypogonadotropic hypogonadism.
Type of Medium:
Online Resource
ISSN:
2308-1430
,
0375-9660
DOI:
10.14341/probl2014606
DOI:
10.14341/probl201460638-44
Language:
Unknown
Publisher:
Endocrinology Research Centre
Publication Date:
2014
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