In:
European Journal of Ophthalmology, SAGE Publications, Vol. 21, No. 3 ( 2011-05), p. 237-242
Abstract:
TO investigate femtosecond laser-assisted nanosurgery of the anterior lens capsule in a prospective in vitro study. Methods Eight anterior lens capsules obtained during conventional phaco surgery were irradiated with a nonamplified 80-MHz near-infrared 800-nm titanium:sapphire femtosecond laser. Line intratissue laser cuts were examined by femtosecond multiphoton laser scanning microscopy (MLSM) and transmission electron microscopy (TEM). Results Speed parameters of the laser beam, laser ablation time, and pulse power determined the width of the lesions, which ranged from 220±40 nm (SD) to 1.49±0.15 μm. Both MLSM and TEM revealed minimal collateral alterations in the tissue surrounding the laser cuts. Conclusions Nonamplified near-infrared femtosecond laser pulses at low pulse energies may be a promising strategy for precise noncontact nanosurgery of the anterior lens capsule with minimal collateral damage to surrounding tissue. High-resolution MLSM offers 3-dimensional, noninvasive, non-destructive imaging at submicrometer resolution within seconds before and after ablation.
Type of Medium:
Online Resource
ISSN:
1120-6721
,
1724-6016
DOI:
10.5301/EJO.2010.1445
Language:
English
Publisher:
SAGE Publications
Publication Date:
2011
detail.hit.zdb_id:
1475018-1
Permalink