In:
Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 69, No. 2 ( 2010), p. 81-83
Abstract:
〈 i 〉 Background: 〈 /i 〉 Hemolytic disease of the fetus/newborn due to Jr 〈 sup 〉 a 〈 /sup 〉 immunization is very rare and considered to be mild, and only routine obstetrical care is recommended for pregnant women sensitized to the Jr 〈 sup 〉 a 〈 /sup 〉 antigen. 〈 i 〉 Case Report: 〈 /i 〉 A 20-year-old nulliparous woman was referred to our hospital for perinatal management. Her indirect Coombs test was positive for anti-Jr 〈 sup 〉 a 〈 /sup 〉 antibody (1:64). At 33 weeks’ gestational age, we observed that fetal growth was mildly restricted and the peak systolic velocity of the fetal middle cerebral artery (PSV-MCA) was above the upper limit of the reference range (1.55 multiples of the median). Amniocentesis was also carried out and the ΔOD450 value was in the lower mid-zone of the Liley curve. We continued to carefully observe the patient because we observed PSV-MCA values within 1.50–1.60 multiples of the median and no other findings of fetal anemia. She vaginally delivered a female infant weighing 2,136 g at 37 weeks’ gestational age. The infant received treatment with both iron and recombinant erythropoietin without developing hyperbilirubinemia and blood transfusion. 〈 i 〉 Conclusion: 〈 /i 〉 PSV-MCA should be monitored for the detection of fetal anemia, even in pregnant women sensitized to some antigens for which only routine obstetrical care is recommended.
Type of Medium:
Online Resource
ISSN:
0378-7346
,
1423-002X
Language:
English
Publisher:
S. Karger AG
Publication Date:
2010
detail.hit.zdb_id:
1482695-1
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