In:
Journal of Digestive Diseases, Wiley, Vol. 13, No. 10 ( 2012-10), p. 504-509
Kurzfassung:
To evaluate and compare the clinical characteristics, manometric results and treatment outcomes of different subtypes of achalasia in untreated Chinese patients using high‐resolution esophageal manometry. Methods A total of 75 achalasia patients and 34 healthy controls were enrolled in the study, and three achalasia subtypes were determined based on the C hicago classification. Clinical characteristics, manometric and treatment outcomes were compared. Results In all, 25 patients were classified as type I , 46 as type II and 4 as type III . The mean overall length of lower esophageal sphincter ( LES ) in type III was significantly longer than those in the controls and type I patients ( P 〈 0.05), and abdominal LES length was significantly longer in type III than those in controls, type I and type II patients. All subtypes of achalasia had higher resting and residual LES pressures than those found in healthy controls ( P 〈 0.05). Resting upper esophageal sphincter ( UES ) pressure in type III patients was significantly lower than those in healthy controls and type I patients, whereas types I and II patients had higher residual UES pressures compared with healthy controls ( P 〈 0.05). Type II patients had a better response to the treatment than type I and III patients. Conclusions Type II is more common in untreated C hinese achalasia patients, and type II patients had better treatment outcomes than other types of patients. Large‐sample multicenter trials are necessary in the future.
Materialart:
Online-Ressource
ISSN:
1751-2972
,
1751-2980
DOI:
10.1111/cdd.2012.13.issue-10
DOI:
10.1111/j.1751-2980.2012.00622.x
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2012
ZDB Id:
2317117-0
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