Publication Date:
2013-07-18
Description:
Article Tuberous sclerosis is a disease characterized by tumour-like growths in multiple organs and is caused by mutations in TSC1 or TSC2. Here, the authors solve the crystal structure of yeast TSC1 and find that most mutations are found inside the folded N-terminal domain. Nature Communications doi: 10.1038/ncomms3135 Authors: Wei Sun, Ye Julia Zhu, Zhizhi Wang, Qiang Zhong, Feng Gao, Jizhong Lou, Weimin Gong, Wenqing Xu
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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