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  • Articles  (2)
  • Wiley-Blackwell  (2)
  • Singapore : Imprint: Springer
  • 2010-2014  (2)
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  • Articles  (2)
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  • 1
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    Comparing the biological characteristics of adipose tissue-derived stem cells of different persons (2012)
    Wiley-Blackwell
    Details
    Publication Date: 2012-04-16
    Description: Scientists have found that cell sex is a variable that considerably influences the regeneration abilities of muscle-derived stem cells' in mice. We try to find out whether the cell sex or cell age (the age of donor) will influence the biological characteristics of human adipose tissue-derived stem cells (H-ADSCs). The results indicate that cell sex influences the proliferation, differentiation, paracrine, and anti-apoptosis abilities of the H-ADSCs, and cell age may also affect the H-ADSCs' differentiation and anti-apoptosis abilities. J. Cell. Biochem. 113: 2020–2026, 2012. © 2012 Wiley Periodicals, Inc.
    Electronic ISSN: 0091-7419
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Published by Wiley-Blackwell
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  • 2
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    Pharmacokinetics of Terazosin Enantiomers in Healthy Chinese Male Subjects (2012)
    Wiley-Blackwell
    In: Chirality
    Details
    Publication Date: 2012-08-11
    Description: ABSTRACT The purpose of this study was to elucidate the pharmacokinetics of terazosin enantiomers in healthy Chinese male subjects. After a single oral dose of 2-mg terazosin, the plasma concentrations of terazosin enantiomers were measured over the course of 48 h in 12 healthy subjects. The plasma concentrations of (+)-( R )-terazosin at all time points were higher than those of (−)-( S )-terazosin. The area under the plasma concentration–time curve (AUC 0–∞ ) and maximum plasma concentration of (+)-( R )-terazosin were significantly greater than those of the (−)-( S )-terazosin ( P  〈 0.01, respectively). The R / S ratio of AUC 0–∞ of terazosin was 1.68. For the first time, it was proven that the pharmacokinetics of terazosin was stereoselective in healthy Chinese male subjects. Chirality, 2012. © 2012 Wiley Periodicals, Inc.
    Print ISSN: 0899-0042
    Electronic ISSN: 1520-636X
    Topics: Chemistry and Pharmacology
    Published by Wiley-Blackwell
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