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  • 1
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    Online Resource
    In the (Sub)Tropics Allergic Rhinitis and Its Impact on Asthma Classification of Allergic Rhinitis is More Useful than Perennial–Seasonal Classification
    SAGE Publications ; 2014
    In:  American Journal of Rhinology & Allergy Vol. 28, No. 3 ( 2014-05), p. 232-238
    Details
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 28, No. 3 ( 2014-05), p. 232-238
    Abstract: Two different allergic rhinitis (AR) symptom phenotype classifications exist. Treatment recommendations are based on intermittent–persistent (INT-PER) cataloging, but clinical trials still use the former seasonal AR–perennial AR (SAR-PAR) classification. This study was designed to describe how INT-PER, mild–moderate/severe and SAR-PAR of patients seen by allergists are distributed over the different climate zones in a (subtropical country and how these phenotypes relate to allergen sensitization patterns. Methods Six climate zones throughout Mexico were determined, based on National Geographic Institute (Instituto Nacional de Estadística y Geografía) data. Subsequent AR patients (2–68 years old) underwent a blinded, standardized skin-prick test and filled out a validated questionnaire phenotyping AR. Results Five hundred twenty-nine subjects participated in this study. In the tropical zone with 87% house-dust mite sensitization, INT (80.9%; p 〈 0.001) and PAR (91%; p = 0.04) were more frequent than in the subtropics. In the central high-pollen areas, there was less moderate/severe AR (65.5%; p 〈 0.005). Frequency of comorbid asthma showed a clear no -south gradient, from 25% in the dry north to 59% in the tropics (p 〈 0.005). No differences exist in AR cataloging among patients with different sensitization patterns, with two minor exceptions (more PER in tree sensitized and more PAR in mold positives; p 〈 0.05). Conclusion In a (sub)tropical country the SAR-PAR classification seems of limited value and bears poor relation with the INT-PER classification. INT is more frequent in the tropical zone. Because PER has been shown to relate to AR severity, clinical trials should select patients based on INT-PER combined with the severity cataloging because these make for a better treatment guide than SAR-PAR.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    URL: Article
    DOI: 10.2500/ajra.2014.28.4035
    RVK:
    XA 20278
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2554548-6
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  • 2
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    Juvenile Polyposis of Infancy Associated with Paracentric Inversion and Deletion of Chromosome 10 in a Hispanic Patient: A Case Report
    SAGE Publications ; 2010
    In:  Pediatric and Developmental Pathology Vol. 13, No. 6 ( 2010-11), p. 486-491
    Details
    In: Pediatric and Developmental Pathology, SAGE Publications, Vol. 13, No. 6 ( 2010-11), p. 486-491
    Abstract: Juvenile polyposis of infancy is a rare genetic disorder, involving multiple hamartomatous polyps of the gastrointestinal tract, which usually has a very aggressive clinical course and is often fatal. It is characterized by early onset (during the 1st months of life) and by diffuse juvenile polyposis with anemia, recurrent gastrointestinal bleeding, diarrhea, rectal prolapse, intussusception, protein-losing enteropathy, starvation, and malnutrition. There is a hypothesis that mutation of the tumor-suppressor genes BMPR1A and PTEN, located on the long arm of chromosome 10, is associated with the development of this disease. Medical treatment for this disorder is challenging and should be conservative whenever possible. We present the case of a 3-year-old girl with juvenile polyposis of infancy who eventually died from mesenteric artery thrombosis during surgical colectomy. Karyotype of the patient showed a paracentric inversion in 10q and a deletion in 10p. We will briefly comment on some genetic considerations of this disease.
    Type of Medium: Online Resource
    ISSN: 1093-5266 , 1615-5742
    URL: Article
    DOI: 10.2350/10-01-0791-CR.1
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 1480654-X
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  • 3
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    Effects of myofascial release techniques on pain, physical function, and postural stability in patients with fibromyalgia: a randomized controlled trial
    SAGE Publications ; 2011
    In:  Clinical Rehabilitation Vol. 25, No. 9 ( 2011-09), p. 800-813
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 25, No. 9 ( 2011-09), p. 800-813
    Abstract: Objective: To determine the effect of myofascial release techniques on pain symptoms, postural stability and physical function in fibromyalgia syndrome. Design: A randomized, placebo-controlled trial was undertaken. Subjects: Eighty-six patients with fibromyalgia syndrome were randomly assigned to an experimental group and a placebo group. Interventions: Patients received treatments for 20 weeks. The experimental group underwent 10 myofascial release modalities and the placebo group received sham short-wave and ultrasound electrotherapy. Main measures: Outcome variables were number of tender points, pain, postural stability, physical function, clinical severity and global clinical assessment of improvement. Outcome measures were assessed before and immediately after, at six months and one year after the last session of the corresponding intervention. Results: After 20 weeks of myofascial therapy, the experimental group showed a significant improvement ( P   〈   0.05) in painful tender points, McGill Pain Score (20.6 ± 6.3, P  〈  0.032), physical function (56.10 ± 17.3, P  〈  0.029), and clinical severity (5.08 ± 1.03, P  〈  0.039). At six months post intervention, the experimental group had a significantly lower mean number of painful points, pain score (8.25 ± 1.13, P  〈  0.048), physical function (58.60 ± 16.30, P  〈  0.049) and clinical severity (5.28 ± 0.97, P  〈  0.043). At one year post intervention, the only significant improvements were in painful points at second left rib and left gluteal muscle, affective dimension, number of days feeling good and clinical severity. Conclusion: The results suggest that myofascial release techniques can be a complementary therapy for pain symptoms, physical function and clinical severity but do not improve postural stability in patients with fibromyalgia syndrome.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215511399476
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2028323-4
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  • 4
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    Adipose Stromal Vascular Fraction Improves Cardiac Function in Chronic Myocardial Infarction through Differentiation and Paracrine Activity
    SAGE Publications ; 2012
    In:  Cell Transplantation Vol. 21, No. 5 ( 2012-05), p. 1023-1037
    Details
    In: Cell Transplantation, SAGE Publications, Vol. 21, No. 5 ( 2012-05), p. 1023-1037
    Abstract: Fresh adipose-derived cells have been shown to be effective in the treatment of acute myocardial infarction (MI), but their role in the chronic setting is unknown. We sought to determine the long-term effect of the adipose derived-stromal vascular fraction (SVF) cell transplantation in a rat model of chronic MI. MI was induced in 82 rats by permanent coronary artery ligation and 5 weeks later rats were allocated to receive an intramyocardial injection of 10 7 GFP-expressing fresh SVF cells or culture media as control. Heart function and tissue metabolism were determined by echocardiography and 18 F-FDG-microPET, respectively, and histological studies were performed for up to 3 months after transplantation. SVF induced a statistically significant long-lasting (3 months) improvement in cardiac function and tissue metabolism that was associated with increased revascularization and positive heart remodeling, with a significantly smaller infarct size, thicker infarct wall, lower scar fibrosis, and lower cardiac hypertrophy. Importantly, injected cells engrafted and were detected in the treated hearts for at least 3 months, directly contributing to the vasculature and myofibroblasts and at negligible levels to cardiomyocytes. Furthermore, SVF release of angiogenic (VEGF and HGF) and proinflammatory (MCP-1) cytokines, as well as TIMP1 and TIMP4, was demonstrated in vitro and in vivo, strongly suggesting that they have a trophic effect. These results show the potential of SVF to contribute to the regeneration of ischemic tissue and to provide a long-term functional benefit in a rat model of chronic MI, by both direct and indirect mechanisms.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    URL: Article
    DOI: 10.3727/096368911X623862
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2020466-8
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  • 5
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    Short-term effects of spinal thrust joint manipulation in patients with chronic neck pain: a randomized clinical trial
    SAGE Publications ; 2013
    In:  Clinical Rehabilitation Vol. 27, No. 6 ( 2013-06), p. 504-512
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 27, No. 6 ( 2013-06), p. 504-512
    Abstract: To compare the effects of an isolated application of cervical spine thrust joint manipulation vs. the application of cervical, cervico-thoracic junction and thoracic manipulation on neck pain, disability and cervical range of motion in chronic neck pain. Design: Randomized clinical trial. Setting: Clinical practice. Participants: Eighty-two patients (41 females) with chronic mechanical neck pain. Interventions: Patients were randomly assigned to a cervical spine manipulation group or a full manipulative group who received mid-cervical, cervico-thoracic and thoracic joint manipulations. Measurements: Neck pain intensity (11-point numeric pain rating scale), self-reported disability (Neck Disability Index) and cervical range of motion were collected at baseline and one week after the intervention by an assessor blinded to the allocation of the patients. Results: A significant Group * Time interaction for Neck Disability Index ( P = 0.022), but not for neck pain ( P = 0.612), was found: patients in the full manipulative group exhibited greater reduction in disability than those who received the cervical spine manipulation alone, whereas both groups experienced similar decreases in neck pain. Patients in both groups experienced similar increases in cervical range of motion ( P 〉 0.4). No effect of gender was observed ( P 〉 0.299). Conclusions: In patients with chronic mechanical neck pain, manipulation of the cervical and thoracic spine leads to a greater reduction in disability at one week than after manipulation of the cervical spine alone, whereas changes in pain and range of motion are not affected differently.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215512464501
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2028323-4
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  • 6
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    Review: Factor XI Deficiency: Review and Management in Pregnant Women
    SAGE Publications ; 2010
    In:  Clinical and Applied Thrombosis/Hemostasis Vol. 16, No. 2 ( 2010-04), p. 209-213
    Details
    In: Clinical and Applied Thrombosis/Hemostasis, SAGE Publications, Vol. 16, No. 2 ( 2010-04), p. 209-213
    Abstract: Factor XI deficiency is a rare disease found predominantly in Ashkenazi Jews. There is a poor correlation between factor XI level and bleeding in patients with factor XI deficiency. Individuals with severe factor XI deficiency are usually at risk of excessive bleeding after surgery and injury, particularly when trauma involves tissues rich in fibrinolytic activity. Women with partial or severe deficiency are at risk of excessive uterine bleeding during labor. The unpredictable nature of factor XI deficiency complicates management during pregnancy and delivery. This review gives an overview of the management of pregnant women with factor XI deficiency.
    Type of Medium: Online Resource
    ISSN: 1076-0296 , 1938-2723
    URL: Article
    DOI: 10.1177/1076029608327864
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2230591-9
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  • 7
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    Distribución espacial de la riqueza de especies leñosas raras de la Península de Yucatán y su relación con las áreas naturales protegidas
    SAGE Publications ; 2012
    In:  Tropical Conservation Science Vol. 5, No. 3 ( 2012-09), p. 320-339
    Details
    In: Tropical Conservation Science, SAGE Publications, Vol. 5, No. 3 ( 2012-09), p. 320-339
    Abstract: Las especies de plantas raras de las selvas en la Península de Yucatán aún no han sido evaluadas como un grupo particular. Se seleccionó un conjunto de especies leñosas raras (ELR) de las selvas tropicales de la Península de Yucatán. Se estimó la riqueza de especies, sumando los mapas de distribución potencial de cada especie, y se evaluó su relación con las Áreas Naturales Protegidas (ANP) de la península. Se identificaron 3 niveles de rareza -bajo, medio y alto-, de acuerdo a la frecuencia, la especificidad de hábitat y el rango de distribución potencial de las especies seleccionadas. Se identificaron 4 regiones de mayor riqueza de ELR. Todas las regiones incluyeron especies del nivel de rareza bajo, 3 regiones incluyeron especies de nivel medio y sólo una región incluyó especies extremadamente raras (nivel alto); esta región está fuera de las ANP establecidas. La riqueza de ELR se asoció positivamente con el tamaño de las ANP. Este estudio representa el primer esfuerzo para conocer a las especies leñosas raras de la Península de Yucatán, sus patrones de distribución potencial y evaluar su estado de protección actual. Nuestros resultados sugieren que las ANP actuales podrían estar preservando la riqueza de ELR del nivel bajo y medio de rareza, pero no la riqueza de las especies extremadamente raras. Por lo tanto, es prioritario el establecimiento de ANP en la región en la que podría concentrarse la más alta riqueza de estas especies, que son particularmente vulnerables a la extinción.
    Type of Medium: Online Resource
    ISSN: 1940-0829 , 1940-0829
    URL: Article
    DOI: 10.1177/194008291200500307
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2496920-5
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  • 8
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    New regulation of the right to a dignified dying in Spain: Repercussions for nursing
    SAGE Publications ; 2012
    In:  Nursing Ethics Vol. 19, No. 5 ( 2012-09), p. 619-628
    Details
    In: Nursing Ethics, SAGE Publications, Vol. 19, No. 5 ( 2012-09), p. 619-628
    Abstract: Preserving dignity during the dying process requires reviewing the roles of those involved in the treatment, care methods and decision-making. This article examines the participation and responsibility assigned to nurses regarding decision-making in the final stages of life, as laid out in the Rights to and Guarantee of Dignity for the Individual During the Process of Death Act. This text has been analysed on the levels of socio-cultural practice and discourse practice, using the critical discourse analysis methodology. The results show that, although the law is another result of the social trend of patient empowerment, the responsibility of the nurses is not recognised, and they are left out of the decision-making process in the final stages of life.
    Type of Medium: Online Resource
    ISSN: 0969-7330 , 1477-0989
    URL: Article
    DOI: 10.1177/0969733011429016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2031461-9
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  • 9
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    Short-term effects of interferential current electro-massage in adults with chronic non-specific low back pain: a randomized controlled trial
    SAGE Publications ; 2013
    In:  Clinical Rehabilitation Vol. 27, No. 5 ( 2013-05), p. 439-449
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 27, No. 5 ( 2013-05), p. 439-449
    Abstract: To analyse the effectiveness of a combined procedure of massage and electrotherapy with interferential current in individuals with chronic non-specific low back pain of mechanical aetiology. Design: A single blinded randomized controlled trial. Setting: Clinical setting. Participants: Sixty-two individuals with chronic non-specific low back pain were randomly assigned to an experimental or control group. For 10 weeks the experimental group underwent treatment comprising 20 sessions (twice a week) of massage with interferential current in the lumbar and dorsal–lumbar area, and the control group received superficial lower back massage (effleurage, superficial pressure and skin rolling). Main outcome variables: Oswestry Disability Index, pain visual analogue scale, Tampa Scale for Kinesiophobia, Roland Morris Disability Questionnaire, McQuade Test, Side Bridge Test, quality of life scores and the range of trunk anteflexion motion, which were all assessed before the treatment and immediately after the last treatment session. Results: The 2 × 2 mixed model ANOVA with repeated measurements showed statistically significant group * time interactions for the visual analogue scale ( F = 12.839; P = 0.001), Oswestry Disability Index ( F = 5.850; P = 0.019), Roland Morris Disability Questionnaire ( F = 8.237; P = 0.006) and quality of life (physical function ( F = 16.792; P = 0.001), physical role ( F = 14.839; P = 0.001) and body pain ( F = 11.247; P = 0.001)). Conclusions: In individuals with chronic non-specific low back pain, interferential current electro-massage achieved a significantly greater improvement in disability, pain and quality of life in comparison to superficial massage after 20 treatment sessions.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215512460780
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2028323-4
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  • 10
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    In-Hospital Complications and Mortality Following Major Lower Extremity Amputations in a Series of Predominantly Diabetic Patients
    SAGE Publications ; 2010
    In:  The International Journal of Lower Extremity Wounds Vol. 9, No. 1 ( 2010-03), p. 16-23
    Details
    In: The International Journal of Lower Extremity Wounds, SAGE Publications, Vol. 9, No. 1 ( 2010-03), p. 16-23
    Abstract: The purpose of this study was to analyze the outcomes of major lower extremity amputations (MLEAs) in a series, including diabetic patients, with the aim to study whether diabetes mellitus is a risk factor of in-hospital mortality and perioperative complications. A retrospective analysis of 283 MLEAs (221 of these patients were diabetic and 62 were nondiabetic) performed between January 1, 1998, and December 31, 2008, at the General Surgery Department and Diabetic Foot Unit of La Paloma Hospital in Las Palmas de Gran Canaria (Canary Islands) was done. The significant risk factors of mortality were 〉 " xbd="324" xhg="301" ybd="1481" yhg="1446"/ 〉 75 years of age (odds ratio [OR] = 4.1, 95% confidence interval [CI] = 1.4-11.7), postoperative cardiac complications (OR = 12.3, 95% CI = 3.7-40.2) and postoperative respiratory complications (OR = 3.8, 95% CI = 1.0-13.3). No statistically significant risk factors were found related to the presence of systemic and wound-related complications. In diabetic patients, the significant risk factors of mortality were postoperative cardiological complications (OR = 13.6, 95% CI = 3.1-59.6), postoperative respiratory complications (OR = 5.9, 95% CI = 1.0-35.5), and first episode of amputation (OR = 5.9, 95% CI = 1.4-24.3). There were no statistically significant differences in the outcome of major amputations between diabetic and nondiabetic patients. Hospital stay was significantly longer in diabetic patients ( P 〈 .01) though when the patients with diabetic foot infections were excluded, this difference was not found.
    Type of Medium: Online Resource
    ISSN: 1534-7346 , 1552-6941
    URL: Article
    DOI: 10.1177/1534734610361946
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2135166-1
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