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  • SAGE Publications  (2)
  • 2010-2014  (2)
  • 1
    Online Resource
    Online Resource
    Analysis of prognostic factors associated with longitudinally extensive transverse myelitis
    SAGE Publications ; 2013
    In:  Multiple Sclerosis Journal Vol. 19, No. 6 ( 2013-05), p. 742-748
    Details
    In: Multiple Sclerosis Journal, SAGE Publications, Vol. 19, No. 6 ( 2013-05), p. 742-748
    Abstract: The aim of this study is to report the clinical profile and outcome of longitudinally extensive transverse myelitis (LETM). Methods: We prospectively studied adult patients who presented with LETM from January 2008 to December 2011. Information on demographic, clinical course, magnetic resonance imaging (MRI) and outcome was collected. HLA-DRB1 genotype was compared with those of 225 normal controls and patients with MS (228) and neuromyelitis optica (NMO) (22). Results: In total, 23 patients (16 female) with a median age of 44.5 years (range: 20–77 years) were included. Most (74%) had moderate–severe disability at nadir (48% non-ambulatory), normal/non-multiple sclerosis (MS) brain MRI (96%) and a median MRI cord lesion of 5 vertebral segments (range: 3–19). Laboratory analysis showed cerebrospinal fluid pleocytosis (45%), NMO-IgG (9%), antinuclear antibodies (70%), and genotype HLA-DRB1*13 (57%). The frequency of DRB1*13 genotype was higher compared with controls ( p=0.002), MS ( p=0.001) and NMO ( p= 0.003) patients. After a median follow-up of 32 months, one patient converted to MS, two had relapsing LETM with NMO-IgG, and 20 remained as idiopathic with recurrences in four (20%). Twelve (52%) patients recovered with minimal disability (Expanded Disability Status Scale (EDSS) 〈 2.5) and three (13%) remained wheelchair dependent. Disability at nadir was associated with the final outcome and extension of the spinal cord lesion with risk of recurrence. Recurrence was not associated with worse outcome. Conclusions: Inflammatory LETM is mostly idiopathic with a good outcome. It includes a relatively homogenous group of patients with an overrepresentation of the HLA-DRB1*13 genotype. EDSS at nadir is a predictor of the final outcome and extension of the myelitis of the recurrence risk.
    Type of Medium: Online Resource
    ISSN: 1352-4585 , 1477-0970
    URL: Article
    DOI: 10.1177/1352458512461968
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2008225-3
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Effect of the structural components of support on the loss of mechanical properties of football fields of artificial turf
    SAGE Publications ; 2014
    In:  Proceedings of the Institution of Mechanical Engineers, Part P: Journal of Sports Engineering and Technology Vol. 228, No. 3 ( 2014-09), p. 155-164
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part P: Journal of Sports Engineering and Technology, SAGE Publications, Vol. 228, No. 3 ( 2014-09), p. 155-164
    Abstract: Football fields of artificial turf are in constant evolution. The resulting improvements have given rise to a large diversity of structural components. There are various types of infill and fibre for artificial turf and different designs and materials for the support structure (sub-base and elastic layer). The design of the sub-base and the presence or absence of the elastic layer can influence turf performance and the surface’s useful lifetime. The aim of this study was to assess in situ the effect of the various support structures on the mechanical properties of artificial turf after deterioration caused by wear for a year. The assessed properties were force reduction (%), standard vertical deformation (mm), rotational traction (N·m), vertical ball rebound (%), and ball roll (m), according to the requirements in norm EN 15330-1:2007. The results demonstrate the effect of the structural base on the mechanical and functional performance of football fields of artificial turf, as well as the significant deterioration of the properties over a year which varied between 3.14% and 8.92% with regard to the installed system. These results show that the support structure that provides the greatest durability and adequate behaviour of the mechanical properties over time is that which has a sub-base of compacted gravel under an elastic layer.
    Type of Medium: Online Resource
    ISSN: 1754-3371 , 1754-338X
    URL: Article
    DOI: 10.1177/1754337114527276
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2433576-9
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