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  • 11
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    Abnormal percolative transport and colossal electroresistance induced by anisotropic strain in (011)-Pr0.7(Ca0.6Sr0.4)0.3MnO3/PMN-PT heterostructure (2014)
    Nature Publishing Group (NPG)
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    Publication Date: 2014-11-18
    Description: Abnormal percolative transport in inhomogeneous systems has drawn increasing interests due to its deviation from the conventional percolation picture. However, its nature is still ambiguous partly due to the difficulty in obtaining controllable abnormal percolative transport behaviors. Here, we report the first observation of electric-field-controlled abnormal percolative transport in (011)-Pr0.7(Ca0.6Sr0.4)0.3MnO3/0.7Pb(Mg1/3Nb2/3)O3-0.3PbTiO3 heterostructure. By introducing an electric-field-induced in-plane anisotropic strain-field in a phase separated PCSMO film, we stimulate a significant inverse thermal hysteresis (~ -17.5 K) and positive colossal electroresistance (~11460%), which is found to be crucially orientation-dependent and completely inconsistent with the well accepted conventional percolation picture. Further investigations reveal that such abnormal inverse hysteresis is strongly related to the preferential formation of ferromagnetic metallic domains caused by in-plane anisotropic strain-field. Meanwhile, it is found that the positive colossal electroresistance should be ascribed to the coactions between the anisotropic strain and the polarization effect from the poling of the substrate which leads to orientation and bias-polarity dependencies for the colossal electroresistance. This work unambiguously evidences the indispensable role of the anisotropic strain-field in driving the abnormal percolative transport and provides a new perspective for well understanding the percolation mechanism in inhomogeneous systems. Scientific Reports 4 doi: 10.1038/srep07075
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Nature Publishing Group (NPG)
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  • 12
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    Partial melting of deeply subducted eclogite from the Sulu orogen in China (2014)
    Nature Publishing Group (NPG)
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    Publication Date: 2014-12-19
    Description: Article Natural examples of eclogite-derived migmatite were previously unknown. Here, the authors show evidence of high-pressure melting of eclogite in the Sulu orogen of China, and suggest the melts represent an exhumed example of flow channels in the lower crust, possibly a source of syn-exhumation magmas. Nature Communications doi: 10.1038/ncomms6604 Authors: Lu Wang, Timothy M. Kusky, Ali Polat, Songjie Wang, Xingfu Jiang, Keqing Zong, Junpeng Wang, Hao Deng, Jianmin Fu
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 13
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    Accurate in silico identification of species-specific acetylation sites by integrating protein sequence-derived and functional features (2014)
    Nature Publishing Group (NPG)
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    Publication Date: 2014-07-22
    Description: Lysine acetylation is a reversible post-translational modification, playing an important role in cytokine signaling, transcriptional regulation, and apoptosis. To fully understand acetylation mechanisms, identification of substrates and specific acetylation sites is crucial. Experimental identification is often time-consuming and expensive. Alternative bioinformatics methods are cost-effective and can be used in a high-throughput manner to generate relatively precise predictions. Here we develop a method termed as SSPKA for species-specific lysine acetylation prediction, using random forest classifiers that combine sequence-derived and functional features with two-step feature selection. Feature importance analysis indicates functional features, applied for lysine acetylation site prediction for the first time, significantly improve the predictive performance. We apply the SSPKA model to screen the entire human proteome and identify many high-confidence putative substrates that are not previously identified. The results along with the implemented Java tool, serve as useful resources to elucidate the mechanism of lysine acetylation and facilitate hypothesis-driven experimental design and validation. Scientific Reports 4 doi: 10.1038/srep05765
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Nature Publishing Group (NPG)
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