In:
Blood, American Society of Hematology, Vol. 121, No. 26 ( 2013-06-27), p. 5158-5166
Abstract:
Loss of the oxygen sensor PHD2 in the HSC compartment in mice results in the HIF1α-driven induction of multipotent progenitors. PHD2-deficient hematopoietic progenitors are outcompeted during severe stress while HSCs are encouraged to self-renew.
Type of Medium:
Online Resource
ISSN:
0006-4971
,
1528-0020
DOI:
10.1182/blood-2012-12-471185
Language:
English
Publisher:
American Society of Hematology
Publication Date:
2013
detail.hit.zdb_id:
1468538-3
detail.hit.zdb_id:
80069-7
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