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  • Nature Publishing Group (NPG)  (14)
  • Oxford University Press  (7)
  • BioMed Central  (6)
  • Wiley-Blackwell  (5)
  • Alzenau : Continental Safety Engineering Int. GmbH (CSE)  (1)
  • American Heart Association (AHA)  (1)
  • BTU  (1)
  • Bayerische Akademie der Wissenschaften, Kommission für Erdmessung und Glaziologie  (1)
  • 2010-2014  (36)
Document type
Publisher
Language
Year
  • 1
    Keywords: Forschungsbericht
    Type of Medium: Online Resource
    Pages: Online-Ressource (PDF-Datei: 61 S., 4.078 KB) , zahlr. Ill. u. graph. Darst., Kt.
    Language: German
    Note: Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden , Förderkennzeichen BMWi 19S9022I. - Verbund-Nr. 01075220. - Berichtsbl. u.d.T.: Forschungsinitiative Ko-FAS, Verbundprojekt Ko-PER: Fahrerassistenz und präventive Sicherheit mittels Kooperative Perzeption, Teilvorhaben: Continental Safty Engineerung International GmbH. - Engl. Berichtsbl. u.d.T.: Research initiative Ko-FAS, cooperative project Ko-PER: Driver assistance and preventive safety via cooperative perception , Systemvoraussetzungen: Acrobat reader. , Zsfassungen in dt. u. engl. Sprache
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  • 2
    Publication Date: 2011-09-29
    Description: SUMMARY We propose a class of spherical wavelet bases for the analysis of geophysical models and for the tomographic inversion of global seismic data. Its multiresolution character allows for modelling with an effective spatial resolution that varies with position within the Earth. Our procedure is numerically efficient and can be implemented with parallel computing. We discuss two possible types of discrete wavelet transforms in the angular dimension of the cubed sphere. We describe benefits and drawbacks of these constructions and apply them to analyse the information in two published seismic wave speed models of the mantle, using the statistics of wavelet coefficients across scales. The localization and sparsity properties of wavelet bases allow finding a sparse solution to inverse problems by iterative minimization of a combination of the ℓ 2 norm of the data residuals and the ℓ 1 norm of the model wavelet coefficients. By validation with realistic synthetic experiments we illustrate the likely gains from our new approach in future inversions of finite-frequency seismic data.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 3
    Publication Date: 2011-05-21
    Description: ABSTRACT Riffle-pool sequences are a common feature of gravel-bed rivers. However, mechanisms of their generation and maintenance are still not fully understood. In this study a monitoring approach similar to the one of Andrews (1979 and 1982) is employed. It focuses on analysing cross-sectional and longitudinal channel geometry of a large floodplain river (Vereinigte Mulde, Sachsen-Anhalt, Germany) with a high temporal and spatial resolution, in order to conclude from stage-dependant morphometric changes to riffle and pool maintaining processes. In accordance with Richards (1976a), Andrews (1979 and 1982) among others, pool cross sections of the Mulde River are narrow and riffle cross sections are wide suggesting that they should rather be addressed as two general types of channel cross-sections than solely as bedforms. At high flows, riffles and pools in the study reaches changed in length and height but not in position. Pools were scoured and riffles aggraded, a development which was reversed during receding flows below the threshold of 0.4·Q bf (40% bankfull discharge). An index for the longitudinal amplitude of riffle-pool sequences, the bed undulation intensity or bedform amplitude, is introduced and proved to be highly significant as a form parameter, its first derivative as a process parameter. The process of pool scour and riffle fill is addressed as bedform maintenance or bedform accentuation. It is indicated by increasing longitudinal bed amplitudes. According to the observed dynamics of bed amplitudes, maintenance of riffle-pool sequences lags behind discharge peaks. Maximum bed amplitudes may be reached with a delay of several days after peak discharges. Increasing bed undulation intensity is interpreted to indicate bed mobility. Post-flood decrease of the bed undulation intensity indicates a retrograde phase when transport from pools to riffles has ceased and bed mobility is restricted to riffle tails and heads of pools. This type of transport behaviour is referred to as disconnected mobility. The comparison of two river reaches, one with undisturbed sediment supply, the other with sediment deficit, suggests that high bed undulation intensity values at low flows indicate sediment deficit and potentially channel degrading conditions. It is more generally hypothesised that channel bed undulations constitute a major component of form roughness and that increased bed amplitudes are an important feature of channel bed adjustment to sediment deficit be it temporally during late floods or permanently due to a supply limitation of bedload. Copyright © 2011 John Wiley & Sons, Ltd.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley-Blackwell
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  • 4
    Publication Date: 2013-03-19
    Description: A randomized comparison of a commercially available portion-controlled weight-loss intervention with a diabetes self-management education program Nutrition & Diabetes 3, e63 (March 2013). doi:10.1038/nutd.2013.3 Authors: G D Foster, T A Wadden, C A LaGrotte, S S Vander Veur, L A Hesson, C J Homko, B J Maschak-Carey, N R Barbor, B Bailer, L Diewald, E Komaroff, S J Herring & M L Vetter
    Keywords: portion controldiabetesobesityglycemic controldiabetes education
    Electronic ISSN: 2044-4052
    Topics: Medicine
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  • 5
    Publication Date: 2013-05-03
    Description: EMBO Reports 14, 465 (2013). doi:10.1038/embor.2013.37 Authors: Denise Wätzlich, Ingrid Vetter, Katja Gotthardt, Mandy Miertzschke, Yong-Xiang Chen, Alfred Wittinghofer & Shehab Ismail Defects in primary cilia result in human diseases known as ciliopathies. The retinitis pigmentosa GTPase regulator (RPGR), mutated in the most severe form of the eye disease, is located at the transition zone of the ciliary organelle. The RPGR-interacting partner PDEδ is involved in trafficking
    Keywords: ciliary traffickingretinitis pigmentosaRPGRArl2/Arl3PDEδ
    Print ISSN: 1469-221X
    Electronic ISSN: 1469-3178
    Topics: Biology , Medicine
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  • 6
    Publication Date: 2012-10-04
    Description: Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling The EMBO Journal 31, 3795 (2012). doi:10.1038/emboj.2012.207 Authors: Irina Vetter, Filip Touska, Andreas Hess, Rachel Hinsbey, Simon Sattler, Angelika Lampert, Marina Sergejeva, Anastasia Sharov, Lindon S Collins, Mirjam Eberhardt, Matthias Engel, Peter J Cabot, John N Wood, Viktorie Vlachová, Peter W Reeh, Richard J Lewis & Katharina Zimmermann Ciguatoxins are sodium channel activator toxins that cause ciguatera, the most common form of ichthyosarcotoxism, which presents with peripheral sensory disturbances, including the pathognomonic symptom of cold allodynia which is characterized by intense stabbing and burning pain in response to mild cooling. We show that
    Keywords: ciguatoxincold allodyniaNavnociceptorTRPA1
    Print ISSN: 0261-4189
    Electronic ISSN: 1460-2075
    Topics: Biology , Medicine
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  • 7
    Publication Date: 2014-07-18
    Description: Article Growing polymer chains are often confined within vesicles in biological systems. Here, the authors study how material properties such as friction, flexibility and thickness affect confined polymer filaments when they grow beyond their equilibrium size, identifying four unique morphologies. Nature Communications doi: 10.1038/ncomms5437 Authors: R. Vetter, F. K. Wittel, H. J. Herrmann
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2014-07-10
    Description: The National Cancer Institute (NCI) Symptom Management and Health-Related Quality of Life Steering Committee convened four working groups to recommend core sets of patient-reported outcomes to be routinely incorporated in clinical trials. The Prostate Cancer Working Group included physicians, researchers, and a patient advocate. The group’s process included 1) a systematic literature review to determine the prevalence and severity of symptoms, 2) a multistakeholder meeting sponsored by the NCI to review the evidence and build consensus, and 3) a postmeeting expert panel synthesis of findings to finalize recommendations. Five domains were recommended for localized prostate cancer: urinary incontinence, urinary obstruction and irritation, bowel-related symptoms, sexual dysfunction, and hormonal symptoms. Four domains were recommended for advanced prostate cancer: pain, fatigue, mental well-being, and physical well-being. Additional domains for consideration include decisional regret, satisfaction with care, and anxiety related to prostate cancer. These recommendations have been endorsed by the NCI for implementation.
    Electronic ISSN: 1460-2105
    Topics: Medicine
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  • 9
    Publication Date: 2012-12-18
    Description: We report on the calibration of the one-dimensional hydrodynamic lake model DYRESM to simulate the water temperature conditions of the pre-alpine Lake Ammersee (South-east Germany) which is representative of deep and large lakes in this region. Special focus is given to the calibration in order to reproduce the correct thermal distribution and stratification including the time of onset and duration of summer stratification. To ensure the application of the model to investigate the impact of climate change on lakes, an analysis of the model sensitivity under stepwise modification of meteorological input parameters (air temperature, wind speed, precipitation, global radiation, cloud cover, vapor pressure, and tributary water temperature) was conducted. The total mean error of the calibration results is –0.23 °C, the root mean square error amounts to 1.012 °C. All characteristics of the annual stratification cycle were reproduced accurately by the model. Additionally, the simulated deviations for all applied modifications of the input parameters for the sensitivity analysis can be differentiated in the high temporal resolution of monthly values for each specific depth. The smallest applied alteration to each modified input parameter caused a maximum deviation in the simulation results of at least 0.26 °C. The most sensitive reactions of the model can be observed through modifications of the input parameters air temperature and wind speed. Hence the results show that further investigations at Lake Ammersee, such as coupling the hydrodynamic model with chemo-dynamic models to assess the impact of changing climate on biochemical conditions within lakes, can be carried out using DYRESM. Copyright © 2012 John Wiley & Sons, Ltd.
    Print ISSN: 0885-6087
    Electronic ISSN: 1099-1085
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Published by Wiley-Blackwell
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  • 10
    Publication Date: 2013-05-09
    Description: Measurements of trace metal ratios in foraminiferal calcite are routinely used to reconstruct paleoceanographic conditions. Analyses using solution-based inductively coupled plasma mass spectrometry (ICP-MS) require dissolution of the entire foraminifer shell. The potential exists for contamination from adherent clays, mineralized coatings, and other diagenetic components that confound the biogenic trace metal signal. We present results from a cleaning experiment on fossil specimens of the planktic foraminifer Orbulina universa that were cracked into several shell fragments and subjected to different cleaning protocols. We use LA-ICP-MS depth profiling to evaluate the effects of reductive, oxidative, and chelating (DTPA) cleaning protocols on shell Mg/Ca and Ba/Ca ratios. Using the natural pattern of intrashell Mg/Ca heterogeneity exhibited by O. universa , we demonstrate that reductive and oxidative cleaning can dissolve shell calcite from available surfaces, although intrashell Mg/Ca minima and maxima are unaffected. High-resolution depth profiles can be used to identify areas of heterogeneous intrashell Ba/Ca, which can be excluded from computations of whole-shell Ba/Ca. The size and density of shell pores plays a major role in the degree of contamination from sedimentary material. We demonstrate an approach for computing whole-shell Me/Ca ratios from LA-ICP-MS depth profiles that accounts for potential contamination and diagenetic overprinting.
    Electronic ISSN: 1525-2027
    Topics: Chemistry and Pharmacology , Geosciences , Physics
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