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  • 1
    Online Resource
    Online Resource
    London :Taylor & Francis Group,
    Keywords: Restoration ecology. ; Electronic books.
    Description / Table of Contents: What is a natural habitat? Who can define what is natural when species and ecosystems constantly change over time, with or without human intervention? When a polluted river or degraded landscape is restored from its damaged state, what is the appropriate outcome? With climate change now threatening greater disruption to the stability of ecosystems, how should restoration ecologists respond? Ecological Restoration and Environmental Change addresses and challenges some of these issues which question the core values of the science and practice of restoration ecology. It analyzes the paradox arising from the desire to produce ecological restorations that fit within an historical ecological context, produce positive environmental benefits and also result in landscapes with social meaning. Traditionally restorationists often felt that by producing restorations that matched historic ecosystems they were following nature's plans and human agency played only a small part in restoration. But the author shows that in reality the process of restoration has always been defined by human choices. He examines the development of restoration practice, especially in North America, Europe and Australia, in order to describe different models of restoration with respect to balancing ecological benefit and cultural value. He develops ways to balance more actively these differing areas of concern while planning restorations. The book debates in detail how coming global climate change and the development of novel ecosystems will force us to ask new questions about what we mean by good ecological restoration. When the environment is constantly shifting, restoration to maintain biodiversity, local species, and ecosystem functions becomes even more challenging. It is likely that in the future ecological restoration will become a never-ending, continuously evolving process.
    Type of Medium: Online Resource
    Pages: 1 online resource (265 pages)
    Edition: 1st ed.
    ISBN: 9781136466366
    DDC: 639.9
    Language: English
    Note: Cover -- Title -- Copyright -- Dedication -- Contents -- List of Illustrations -- Acknowledgments: A beginning -- 1 You can't not choose -- 2 How did we get here? A brief history of ecological restoration -- 3 Restoration is an active choice -- 4 Climate change: Is rapid pace and magnitude a bridge too far for ecological restoration? -- 5 Novel ecosystems: A new wrinkle for ecological restoration -- 6 Geographical variation in attitudes to ecological restoration and why it matters -- 7 Renewed restoration: Building a middle path toward a restored earth -- 8 Building the restored future: Making the renewal happen -- References -- Index.
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  • 2
    Description / Table of Contents: Intro -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Introduction -- Why Cancer? -- New Theories of Carcinogenesis -- The Cell Attractors Theory -- The Link between Ageing and CRCs -- The Robustness that DAF-21/HSP90 Chaperone Mediates Genome Evolution -- The Development Robustness that DAF-12 Hormonal Signaling Buffers of Dauer &lt -- -&gt -- Adult Switch -- The Robustness that the Synmuvb Pathway Buffers Temperature Stress -- The Robustness that Pcg Complex Supports Developmental Plasticity &lt -- -&gt -- Differentiation Onset Decision -- The Robustness that HPL-2/Myb-Muvb Complex Determines -- Sex Decision -- The Robustness Inherent within CRC-Linked Stemness/Pluripotency -- CRCs and Carcinogenesis -- CRC Reprogramming and the Matter of Reversibility -- Conclusion -- References -- Index -- Blank Page.
    Type of Medium: Online Resource
    Pages: 1 online resource (57 pages)
    Edition: 1st ed.
    ISBN: 9781619421066
    Series Statement: Cancer Etiology, Diagnosis and Treatments Series
    Language: English
    Note: Description based on publisher supplied metadata and other sources
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  • 3
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 516 (1987), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Organometallics 4 (1985), S. 396-398 
    ISSN: 1520-6041
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1432
    Keywords: Duplications ; Complementation ; Drosophila melanogaster ; Maroon-like ; Rosy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Gene duplications must play an important role in the evolutionary development of living organisms. Presented here is a general scheme that uses complementary alleles to isolate gene duplications in diploid organisms. The technique was used inDrosophila melanogaster to assess the rate of spontaneous gene duplication at two loci, maroon-like and rosy. The results indicate (1) that the rate of duplication of the maroon-like locus is on the order of 2.7×10−6; (2) that the rate of duplication of the rosy locus is approximately 1.7×10−4; and (3) that duplication occurs in males, suggesting that there may actually be two modes of gene duplication inDrosophila melanogaster.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 14 (1989), S. 113-114 
    ISSN: 1432-0509
    Keywords: Stomach, pseudocyst ; Pancreatitis, complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors describe a case of pancreatic pseudocyst presenting as an intramural gastric mass on upper gastrointestinal examination (UGI) and computed tomography (CT) of the abdomen. The correct diagnosis of this rare entity was suggested preoperatively on the basis of the radiographic findings presented herein.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Heat shock has a profound influence on the metabolism and behavior of eukaryotic cells. We have examined the effects of heat shock on the release from cells of arachidonic acid and its bioactive eicosanoid metabolites, the prostaglandins and leukotrienes. Heat shock (42-45°) increased the rate of arachidonic acid release from human, rat, murine, and hamster cells. Arachidonate accumulation appeared to be due, at least partially, to stimulation of a phospholipase A2 activity by heat shock and was accompanied by the accumulation of lysophosphatidyl-inositol and lysophosphatidylcholine in membranes. Induction of arachidonate release by heat did not appear to be mediated by an increase in cell Ca+ +. Stimulation of arachidonate release by heat shock in hamster fibroblasts was quantitatively similar to the receptor-mediated effects of β thrombin and bradykinin. The effects of heat shock and β thrombin on arachidonate release were inhibited by glucocorticoids. Increased arachidonate release in heat-shocked cells was accompanied by the accelerated accumulation of cyclooxygenase products prostaglandin E2 and prostaglandin F2α and by 5-lipoxygenase metabolite leukotriene B4. Elevated concentrations of arachidonic acid and metabolites may be involved in the cytotoxic effects of hyperthermia, in homeostatic responses to heat shock, and in vascular and inflammatory reactions to stress.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 124 (1985), S. 87-95 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Capillary endothelium can actively regulate vascular permeability of various serum proteins. Hormones such as insulin must interact with this capillary barrier in order to reach their respective target tissues. We have studied the binding and subsequent internalization of 125I-insulin in both native (freshly isolated) and primary cultured capillary endothelium derived from rat epididymal fat pads. Insulin association with the endothelium, internalization and degradation differed between freshly isolated and primary cultured capillaries. Specific binding in freshly isolated and cultured capillaries was temperature dependent, and was competitively inhibited in the presence of unlabelled insulin. Primary cultures of capillaries grown to confluence did not exhibit specific binding of insulin. Despite the lack of specific receptors for insulin, cultured cells vesicularly internalized insulin. Greater than 50% of the total associated insulin was not degraded by cultured endothelium. Morphological examinations using ferritin labelled insulin localized insulin associated to the capillary endothelial cell membrane and sequestered within pinocytotic vesicles. Incubation of freshly isolated capillaries with insulin stimulated the fluid phase endocytosis of 14C-sucrose; however, insulin had no effect on fluid phase endocytosis in cultured capillaries. These results indicate that capillary endothelium, isolated from rat epididymal fat, exhibit specific receptors for insulin. Binding of insulin to the capillary membrane is followed by internalization into cytoplasmic vesicles and partial degradation.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 133 (1987), S. 175-180 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The transport of molecules by nonspecific endocytosis has been described in many cell types, but it has not been characterized in hepatocytes. Because of its central role in the clearance of solutes from portal blood, endocytosis might represent a significant mode of cellular transport. We investigated the mechanism of sucrose uptake in an isolated hepatocyte system. Liver cells were isolated by perfusion and collagenization of rat liver, followed by differential centrifugation. Hepatocytes were then incubated with 14C-sucrose and harvested by spinning through oil in microfuge tubes. Radioactivity was standardized against DNA content. We found that sucrose uptake is concentration-dependent from 5 μM to 100 mM and follows first-order kinetics. Washout studies indicate that exocytosis is responsible for the dynamic equilibrium reached. Arrhenius analysis of temperature dependence yields a linear plot (Ea = 14.2 Kcal/mol). In addition, sucrose uptake is independent of cellular ATP levels. We conclude that sucrose is transported by fluid-phase micropinocytosis in isolated hepatocytes and that this transport mechanism may be important in the uptake of diverse molecules into liver cells.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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